Oltipraz

   
Product Datasheet
Catalog Number:5294
Chemical Name:4-Methyl-5-(2-pyrazinyl)-3H-1,2-dithiole-3-thione
Product Details
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Biological Activity
Nrf2 activator; activates Nrf, which binds to antioxidant response elements (AREs) and induces Phase-I and -II drug-metabolizing enzymes including CYP2B and NQO1. Also increases mRNA levels of multiple hepatic xenobiotic transporters. Elevates expression of genes encoding anti-oxidant and multidrug resistance-associated proteins. Displays chemopreventive activity.
Technical Data
  • M.Wt:
    226.34
  • Formula:
    C8H6N2S3
  • Solubility:
    Soluble to 50 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    64224-21-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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