Oltipraz

Catalog # Availability Size / Price Qty
5294/10
5294/50

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Oltipraz | CAS No. 64224-21-1 | Nrf2 Activators
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Description: Nrf2 activator

Chemical Name: 4-Methyl-5-(2-pyrazinyl)-3H-1,2-dithiole-3-thione

Purity: ≥99%

Product Details
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Biological Activity

Oltipraz is a Nrf2 activator; activates Nrf, which binds to antioxidant response elements (AREs) and induces Phase-I and -II drug-metabolizing enzymes including CYP2B and NQO1. Also increases mRNA levels of multiple hepatic xenobiotic transporters. Elevates expression of genes encoding anti-oxidant and multidrug resistance-associated proteins. Displays chemopreventive activity.

Technical Data

M.Wt:
226.34
Formula:
C8H6N2S3
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
64224-21-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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