Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 97505
View all Orexin A/Hypocretin-1 Primary Antibodies »

Product Specifications

Immunogen

KLH-coupled human Orexin A/Hypocretin‑1 synthetic peptide
Accession # O43612

Specificity

Detects human and mouse Orexin A/Hypocretin‑1. In dot blots, no cross-reactivity with recombinant human Orexin B is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Orexin A/Hypocretin-1 Antibody (97505) [FITC]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from ascites

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Orexin A/Hypocretin-1

FUNCTION: Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity (By similarity). SUBCELLULAR LOCATION: Endoplasmic reticulum; rough endoplasmic reticulum (By similarity). Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses (By similarity). SIMILARITY: Belongs to the orexin family.

Alternate Names

HCRT, Hcrt1, Hypocretin-1, Hypocretin1

Gene Symbol

HCRT

Additional Orexin A/Hypocretin-1 Products

Product Documents for Orexin A/Hypocretin-1 Antibody (97505) [FITC]

Certificate of Analysis

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Product Specific Notices for Orexin A/Hypocretin-1 Antibody (97505) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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