Orexin R1/HCRTR1 Antibody - BSA Free

Novus Biologicals | Catalog # NLS6641

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Rat, Monkey, Primate

Cited:

Human

Predicted:

Canine (93%), Rabbit (93%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

Synthetic 15 amino acid peptide from 3rd cytoplasmic domain of human Orexin R1/HCRTR1.

Epitope

3rd cytoplasmic domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Mouse (87%), Rat (87%), Hamster (87%), Bovine (87%), Bat (87%).

Specificity

Human Orexin R1/HCRTR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for Orexin R1/HCRTR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Orexin R1/HCRTR1 Antibody - BSA Free [NLS6641]

Immunohistochemistry-Paraffin: Orexin R1/HCRTR1 Antibody - BSA Free [NLS6641]

Immunohistochemistry-Paraffin: Orexin R1/HCRTR1 Antibody [NLS6641] - Analysis of anti-HCRTR1 / Orexin Receptor 1 antibody of rat brain, Purkinje neurons at 6.8 ug/ml.

Applications for Orexin R1/HCRTR1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

6.8 ug/ml
Application Notes
Use in Western blot reported in reported in scientific literature (PMID: 31599699)..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: Orexin R1/HCRTR1

OX1R is an Orexin Receptor selective for orexin A. This receptor participates in the feedback mechanism that regulates feeding behavior and sleep. When activated, OX1R stimulates appetite. OX1R has been implicated in narcolepsy, a sleep/wake disorder. Orexin receptor 1 expression has been documented in adrenal and brain. ESTs have been isolated from brain, pancreas, and lung/spleen libraries.

Long Name

Hypocretin Receptor Type 1

Alternate Names

HCRTR1, OrexinR1, OX1R

Entrez Gene IDs

3061 (Human)

Gene Symbol

HCRTR1

Additional Orexin R1/HCRTR1 Products

Product Documents for Orexin R1/HCRTR1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Orexin R1/HCRTR1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Orexin R1/HCRTR1 Antibody - BSA Free

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Protocols

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