Org 37684 (CAS 213007-95-5): R&D Systems
Catalog Number: 4797
Chemical Name: (3S)-3-[(2,3--Dihydro-5-methoxy-1H-inden-4-yl)oxy]pyrrolidine hydrochloride
Biological Activity
Agonist of 5-HT2 receptors. Exhibits a rank order of potency of 5-HT2C >5-HT2B >5-HT2A (pEC50 values are 8.17, 7.96 and 7.11 respectively, in transfected CHO-K1 cells).
Technical Data
  • M.Wt:
    269.77
  • Formula:
    C14H19NO2.HCl
  • Solubility:
    Soluble to 50 mM in water and to 100 mM in DMSO
  • Storage:
    Desiccate at RT
  • CAS No:
    213007-95-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells.
    Porter et al.
    Br.J.Pharmacol., 1999;128:13
  2. Effects of selected serotonin 5-HT1 and 5-HT2 receptor agonists on feeding behavior: possible mechanisms of action.
    De Vry and Schreiber
    Neurosci.Biobehav.Rev., 2000;24:341

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