pan Cadherin Antibody (S04-5A8)

Name: pan Cadherin Antibody (S04-5A8)
Brand: Novus Biologicals
SKU: NBP3-15073
Price: 489 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-15073

Submit a review

Product Documents

Recombinant Monoclonal Antibody

100% Guarantee

Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S04-5A8 expressed in HEK293

View all Cadherin Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human pan Cadherin (Uniprot#: P12830 P22223 P19022)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

140 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for pan Cadherin Antibody (S04-5A8)

Immunocytochemistry/ Immunofluorescence: pan Cadherin Antibody (S04-5A8) [NBP3-15073]

Immunocytochemistry/Immunofluorescence: pan Cadherin Antibody (S04-5A8) [NBP3-15073] - Immunofluorescence of pan Cadherin (green) in MCF-7 using pan Cadherin antibody at dilution 1/5, and DAPI (blue)

Immunohistochemistry-Paraffin: pan Cadherin Antibody (S04-5A8) [NBP3-15073]

Immunohistochemistry-Paraffin: pan Cadherin Antibody (S04-5A8) [NBP3-15073] - Immunohistochemistry of pan Cadherin in paraffin-embedded Human Cholangiocarcinoma using pan Cadherin Rabbit mAb at dilution 1/50

Applications for pan Cadherin Antibody (S04-5A8)

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Immunoprecipitation

0.0763888888888889

Western Blot

1:1000-1:5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.4), 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cadherin

Cadherins are members of a multigene family of single chain glycoprotein receptors mediating calcium dependent cell-cell adhesion. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherins are expressed in a tissue specific manner and and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to co-operate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play an important part in tumor invasion and metastasis. This product is useful for the detection of members of the cadherin family or genetically engineered proteins containing the C-terminal cadherin tail, and for demonstration of adherens type cell-cell junctions regardless of their cadherin type.

Long Name

Cadherin Pan Specific

Alternate Names

Arc-1, cadherin 1, E-cadherin (epithelial), cadherin 1, type 1, E-cadherin (epithelial), cadherin-1, calcium-dependent adhesion protein, epithelial, CAM 120/80, CD324, CD324 antigen, CDHE, cell-CAM 120/80, ECAD, E-cadherin, Epithelial cadherin, LCAM, UVOE-Cadherin, uvomorulin

Gene Symbol

CDH1

Additional Cadherin Products

Product Documents for pan Cadherin Antibody (S04-5A8)

Download Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for pan Cadherin Antibody (S04-5A8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Adhesion Molecules

Cadherin Superfamily

Customer Reviews for pan Cadherin Antibody (S04-5A8)

There are currently no reviews for this product. Be the first to review pan Cadherin Antibody (S04-5A8) and earn rewards!

Have you used pan Cadherin Antibody (S04-5A8)?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image