PBR Antibody

Novus Biologicals | Catalog # NBP1-51934

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Mouse

Predicted:

Human (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Peptide ELISA, Flow Cytometry

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all PBR Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RDNSGRRGGSRLPE corresponding to C-Terminus according to Uniprot Mouse NP_033905.3.

Epitope

C-RDNSGRRGGSRLPE

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for PBR Antibody

Western Blot: PBR Antibody [NBP1-51934]

Western Blot: PBR Antibody [NBP1-51934]

Western Blot: PBR Antibody [NBP1-51934] - Staining of Mouse Kidney lysate (35 ug protein in RIPA buffer). Antibody at 0.01 ug/mL. Detected by chemiluminescence
Immunohistochemistry-Paraffin: PBR Antibody [NBP1-51934]

Immunohistochemistry-Paraffin: PBR Antibody [NBP1-51934]

Immunohistochemistry-Paraffin: PBR Antibody [NBP1-51934] - Negative Control showing staining of paraffin embedded Mouse Kidney, with no primary antibody.
Flow Cytometry: PBR Antibody [NBP1-51934]

Flow Cytometry: PBR Antibody [NBP1-51934]

Flow Cytometry: PBR Antibody [NBP1-51934] - Flow cytometric analysis of paraformaldehyde fixed NIH3T3 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.
Immunohistochemistry-Paraffin: PBR Antibody [NBP1-51934]

Immunohistochemistry-Paraffin: PBR Antibody [NBP1-51934]

Immunohistochemistry-Paraffin: PBR Antibody [NBP1-51934] - Staining of paraffin embedded Mouse Kidney. Antibody at 10 ug/mL. Heat induced antigen retrieval with citrate buffer pH 6, HRP-Staining (1:500).

Applications for PBR Antibody

Application
Recommended Usage

Flow Cytometry

10 ug/mL

Immunohistochemistry

5 - 10 ug/mL

Immunohistochemistry-Paraffin

5 - 10 ug/mL

Peptide ELISA

Detection limit 1:128000

Western Blot

0.01 - 0.03 ug/mL

Flow Cytometry Panel Builder

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Advanced Features

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PBR

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Long Name

Peripheral-type Benzodiazepine Receptor

Alternate Names

TSPO

Entrez Gene IDs

12257 (Mouse); 24230 (Rat)

Gene Symbol

TSPO

UniProt

NP_033905.3 (Mouse)

Additional PBR Products

Product Documents for PBR Antibody

Certificate of Analysis

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Product Specific Notices for PBR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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