PDGF-BB (Platelet-Derived Growth Factor BB) is a homodimeric molecule expressed by hepatocytes and nonresorbing osteoclasts, and it promotes osteoblast development and bone formation. It is also produced by platelets, macrophages, and mast cells. At sites of injury, it promotes neutrophil and macrophage infiltration for debridement, fibroblast secretion of new extracellular matrix, and IGF-I-mediated re-epithelialization. The traditional receptor for PDGF is either a homodimer or heterodimer created from two type I transmembrane RTKs, PDGF R alpha and PDGF R beta. PDGF-BB has been shown to bind the alpha/alpha homodimer, alpha/beta heterodimer, and the beta/beta homodimer in vitro, and act through the beta/beta homodimer in vivo.
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Monkey PDGF-BB ELISA Kit (Colorimetric)
Novus Biologicals | Catalog # NBP3-49871
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Key Product Details
Sensitivity
18.75 pg/mL
Assay Range
31.25 - 2000 pg/mL
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Product Specifications
Assay Type
Sandwich ELISA
Kit Type
ELISA Kit (Colorimetric)
Species
Monkey
Description
Assay Length: 3 h 30 min
Precision
Intra-Assay Precision (Precision within an assay) CV% 10
Inter-Assay Precision (Precision between assays) CV% 10
Recovery for Monkey PDGF-BB ELISA Kit (Colorimetric)
Recovery
80 - 120%
Linearity
Scientific Data Images for Monkey PDGF-BB ELISA Kit (Colorimetric)
ELISA: Monkey PDGF-BB ELISA Kit (Colorimetric) [NBP3-49871]
Standard Curve Reference.Kit Contents for Monkey PDGF-BB ELISA Kit (Colorimetric)
- Biotinylated Detection Ab Diluent
- Certificate of Analysis
- Concentrated Biotinylated Detection Ab (100x)
- Concentrated HRP Conjugate (100x)
- Concentrated Wash Buffer (25x)
- HRP Conjugate Diluent
- Micro ELISA Plate (Dismountable)
- Plate Sealer
- Product Description
- Reference Standard
- Reference Standard & Sample Diluent
- Stop Solution
- Substrate Reagent
Preparation and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Storage of components varies. See protocol for specific instructions.
Background: PDGF-BB
Long Name
Platelet-derived Growth Factor BB
Alternate Names
PDGFBB
Gene Symbol
PDGFB
Additional PDGF-BB Products
Product Documents for Monkey PDGF-BB ELISA Kit (Colorimetric)
Product Specific Notices for Monkey PDGF-BB ELISA Kit (Colorimetric)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
Related Research Areas
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Protocols
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