PDGF R beta Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-88134

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot, Immunocytochemistry/ Immunofluorescence

Cited:

Western Blot, IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all PDGF R beta Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AQDGTFSSVLTLTNLTGLDTGEYFCTHNDSRGLETDERKRLYIFVPDPTVGFLPNDAEELFIFLTEITEITIPCRVTDPQLVVTLHEKKGDVAL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PDGF R beta Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: PDGF R beta Antibody [NBP1-88134]

Immunocytochemistry/ Immunofluorescence: PDGF R beta Antibody [NBP1-88134]

Immunocytochemistry/Immunofluorescence: PDGF R beta Antibody [NBP1-88134] - Staining of human cell line ASC TERT1 shows localization to the Golgi apparatus & vesicles.
PDGF R beta Antibody - BSA Free Western Blot: PDGF R beta Antibody - BSA Free [NBP1-88134]

Western Blot: PDGF R beta Antibody - BSA Free [NBP1-88134]

Analysis in human cell line U-87 MG.

Applications for PDGF R beta Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PDGF R beta

Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-alpha and PDGF receptor-beta. PDGF receptor-beta can only bind two specific PDGF isoforms, PDGF-beta and PDGF-delta (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.

Long Name

Platelet-derived Growth Factor Receptor beta

Alternate Names

CD140b, PDGFRB

Gene Symbol

PDGFRB

Additional PDGF R beta Products

Product Documents for PDGF R beta Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for PDGF R beta Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for PDGF R beta Antibody - BSA Free

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Protocols

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FAQs

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