Pemoline
Discontinued Product
Chemical Name: 2-Amino-5-phenyl-4(5H)-oxazolone
Purity: ≥99%
Biological Activity
Long-acting central stimulant that induces self-injurious behavior in rats. Acts as an indirect monoamine agonist.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Pemoline (2-Amino-5-phenyl-1,3-oxazol-4-one)-induced self-injurious behavior: a rodent model of pharmacotherapeutic efficacy.
Muehlmann et al.
J.Pharmacol.Exp.Ther., 2008;324:214 -
Pharmacologic control of pem. induced self-injurious behavior in rats.
Mueller and Nyhan
Pharmacol.Biochem.Behav., 1982;16:957 -
Self-injurious behaviour: a comparison of caffeine and pem. models in rats.
Kies and Devine
Pharmacol.Biochem.Behav., 2004;79:587
Product Datasheets
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Citation for Pemoline
The citations listed below are publications that use Tocris products. Selected citations for Pemoline include:
1 Citation: Showing 1 - 1
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Manipulating circadian clock neuron firing rate resets molecular circadian rhythms and behavior.
Authors: Jones Et al.
Nat Neurosci 2015;18:373
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