Catalog Number: 3045
Alternate Names: Phenoxazole, Phenylisohydantoin
Chemical Name: 2-Amino-5-phenyl-4(5H)-oxazolone
Biological Activity
Long-acting central stimulant that induces self-injurious behavior in rats. Acts as an indirect monoamine agonist.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 10 mM in ethanol with gentle warming
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Pharmacologic control of pemoline induced self-injurious behavior in rats.
    Mueller and Nyhan
    Pharmacol.Biochem.Behav., 1982;16:957
  2. Self-injurious behaviour: a comparison of caffeine and pemoline models in rats.
    Kies and Devine
    Pharmacol.Biochem.Behav., 2004;79:587
  3. Pemoline (2-Amino-5-phenyl-1,3-oxazol-4-one)-induced self-injurious behavior: a rodent model of pharmacotherapeutic efficacy.
    Muehlmann et al.
    J.Pharmacol.Exp.Ther., 2008;324:214

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