Perifosine

  
Catalog Number:6087
Alternate Names:KRX-0401
Chemical Name:Octadecyl-(1,1-dimethyl-4-piperidylio) phosphate
Product Details
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Biological Activity
PKB/Akt inhibitor; accumulates in and reorganizes lipid rafts disrupting Akt signaling. Also inhibits MAPK pathway and induces autophagy. Induces apoptosis in leukemia cell lines. Decreases Kv2.1 current amplitude by modulating its inactivation gating. Antitumor. Orally bioavailable.
Technical Data
  • M.Wt:
    461.66
  • Formula:
    C25H52NO4P
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at -20°C
  • CAS No:
    157716-52-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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