[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

  ( 1 citations )    
Product Datasheet
Catalog Number:1092
Chemical Name:
Product Details
Citations (1)
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Biological Activity
Potent agonist of the nociceptin (ORL1) receptor, demonstrated both in vitro and in vivo. Selective, competitive antagonism at the nociceptin receptor has also been reported (pA2 = 7.02 and 6.75 in the guinea pig ileum and mouse vas deferens respectively).
Technical Data
  • M.Wt:
    1367.6
  • Formula:
    C61H102N22O14
  • Sequence:
    FGGFTGARKSARK

    (Modifications: Phe-1 - Gly-2 peptide bond replace with Psi-(CH2-NH), Lys-13 = C-terminal amide)

  • Solubility:
    Soluble to 0.70 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    213130-17-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2 include:

1 Citations: Showing 1 - 1

  1. Nociceptin inhibits cough in the guinea-pig by activation of ORL(1) receptors.
    Authors: McLeod Et al.
    J Biol Chem  2001;132:1175

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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Human ORL1/OPRL1 (NP_000904) VersaClone cDNA

RDC0163
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