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[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

Catalog #: 1092
1 Citation Datasheet / COA / SDS

Discontinued Product

1092 has been discontinued.
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[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2
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Description: Selective nociceptin receptor agonist
Product Details
Citations (1)
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Biological Activity

[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2 is a potent agonist of the nociceptin (ORL1) receptor, demonstrated both in vitro and in vivo. Selective, competitive antagonism at the nociceptin receptor has also been reported (pA2 = 7.02 and 6.75 in the guinea pig ileum and mouse vas deferens respectively).

Technical Data

M.Wt:
1367.6
Formula:
C61H102N22O14
Sequence:
FGGFTGARKSARK

(Modifications: Phe-1 - Gly-2 peptide bond replace with Psi-(CH2-NH), Lys-13 = C-terminal amide)

Solubility:
Soluble to 0.70 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
213130-17-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

The citations listed below are publications that use Tocris products. Selected citations for [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2 include:

1 Citation: Showing 1 - 1

  1. Nociceptin inhibits cough in the guinea-pig by activation of ORL(1) receptors.
    Authors: McLeod Et al.
    J Biol Chem  2001;132:1175

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