Phenobarbital sodium salt
Chemical Name: 5-Ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt
Biological Activity
Enhances GABAergic activity. Long-acting barbiturate; slow-acting barbiturate (Cat. No. 4579) also available.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Phenobarbital but not D.pam reduces AMPA/kainate receptor mediated currents and exerts opposite actions on initial seizures in the neonatal rat hippocampus.
Nardou et al.
Front.Cell.Neurosci., 2011;5:Epub -
Calcium current block by (-)-pentobarbital, phenobarbital, and CHEB but not (+)-pentobarbital in acutely isolated hippocampal CA1 neurons: comparison with effects on GABA-activated Cl- current.
ffrench-Mullen et al.
J.Neurosci., 1993;13:3211
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