Catalog Number: 4578
Chemical Name: 5-Ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt
Biological Activity
Enhances GABAergic activity. Long-acting barbiturate; slow-acting barbiturate (Cat. No. 4579) also available.
Technical Data
  • M.Wt:
    254.22
  • Formula:
    C12H11N2NaO3
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Store at RT
  • CAS No:
    57-30-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Phenobarbital but not diazepam reduces AMPA/kainate receptor mediated currents and exerts opposite actions on initial seizures in the neonatal rat hippocampus.
    Nardou et al.
    Front.Cell.Neurosci., 2011;5:Epub
  2. Calcium current block by (-)-pentobarbital, phenobarbital, and CHEB but not (+)-pentobarbital in acutely isolated hippocampal CA1 neurons: comparison with effects on GABA-activated Cl- current.
    ffrench-Mullen et al.
    J.Neurosci., 1993;13:3211

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