Catalog Number: 1352
Alternate Names: GS peptide-2
Biological Activity
Synthetic peptide suitable as a substrate for glycogen synthase kinase-3 (GSK-3).
Technical Data
  • M.Wt:
    3029
  • Formula:
    C123H191N40O48P
  • Sequence:
    YRRAAVPPSPSLSRHSSPHQSEDEEE

    (Modifications: Ser-21 = OPO3H2)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    851366-97-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in insulin and growth factor signalling.
    Sutherland et al.
    Biochem.J., 1993;296:15
  2. Use of peptide substrates for affinity purification of protein-serine kinases.
    Woodgett
    Anal.Biochem., 1989;180:237
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Phospho-Glycogen Synthase Peptide-2 (substrate) include:

1 Citations: Showing 1 - 1

  1. FRAT-2 preferentially increases glycogen synthase kinase 3 β-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylation.
    Authors: Stoothoff Et al.
    PLoS One 2005;280:270

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