PINX1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-83643

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LNTCHGQETTDSSDKKEKKSFSLEEKSKISKNRVHYMKFTKGKDLSSRSKTDLDCIFGKRQSKKTPEGDASPSTP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (83%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PINX1 Antibody - BSA Free

PINX1 Antibody - BSA Free Immunohistochemistry-Paraffin: PINX1 Antibody - BSA Free [NBP1-83643]

Immunohistochemistry-Paraffin: PINX1 Antibody - BSA Free [NBP1-83643]

Staining of human cerebellum shows strong nuclear positivity in Purkinje and glial cells.
PINX1 Antibody - BSA Free Immunohistochemistry-Paraffin: PINX1 Antibody - BSA Free [NBP1-83643]

Immunohistochemistry-Paraffin: PINX1 Antibody - BSA Free [NBP1-83643]

Staining of human skin shows strong nuclear positivity in squamous epithelial cells.
PINX1 Antibody - BSA Free Immunohistochemistry-Paraffin: PINX1 Antibody - BSA Free [NBP1-83643]

Immunohistochemistry-Paraffin: PINX1 Antibody - BSA Free [NBP1-83643]

Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.
PINX1 Antibody - BSA Free Western Blot: PINX1 Antibody - BSA Free [NBP1-83643]

Western Blot: PINX1 Antibody - BSA Free [NBP1-83643]

Analysis in human cell line K562.

Applications for PINX1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. IF fixation permeabilization: PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PINX1

PINX1 is a protein that contains a TID (telomerase inhibiting domain) domain which is capable of binding MCRS1, TERT and TERF1. PINX1 has been shown to be a potent telomerase inhibitor and putative tumor suppressor.

Alternate Names

FLJ20565, hepatocellular carcinoma-related putative tumor suppressor, Liver-related putative tumor suppressor, LPTLPinX1, LPTS67-11-3 protein, MGC8850, PIN2 interacting protein 1, PIN2/TERF1 interacting, telomerase inhibitor 1, PIN2/TERF1-interacting telomerase inhibitor 1, PIN2-interacting protein 1, Pin2-interacting protein X1, Protein 67-11-3, TRF1-interacting protein 1

Gene Symbol

PINX1

Additional PINX1 Products

Product Documents for PINX1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for PINX1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for PINX1 Antibody - BSA Free

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Protocols

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FAQs

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