Biological ActivityPseudosubstrate peptide inhibitor of protein kinase C (IC50 = 0.18 μM). Attenuates vascular hyperproliferation and hypertrophy induced by high glucose. Inhibits DNA and protein synthesis in vascular smooth muscle cells (VSMCs) in a dose-dependent manner.
Negative Control also available.
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Possible involvement of phospholipase D and protein kinase C in vascular growth induced by elevated glucose concentration
Yasunari et al.
Citation for PKC (19-36)
The citations listed below are publications that use Tocris products. Selected citations for PKC (19-36) include:
1 Citation: Showing 1 - 1
Activation of Phosphatidylinositol-Linked DA Receptors Induces a Facilitation of Glutamate-Mediated Synaptic Transmission in the Lateral Entorhinal Cortex.
Authors: Glovaci and Chapman
Mol Med Rep 2015;10:e0131948
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