Catalog Number: 4058
Biological Activity
Pseudosubstrate peptide inhibitor of protein kinase C (IC50 = 0.18 μM). Attenuates vascular hyperproliferation and hypertrophy induced by high glucose. Inhibits DNA and protein synthesis in vascular smooth muscle cells (VSMCs) in a dose-dependent manner. Inactive control available ([Glu27]-PKC (19-36), Cat. No. 4059).
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:
  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. Possible involvement of phospholipase D and protein kinase C in vascular growth induced by elevated glucose concentration
    Yasunari et al.
    Hypertension, 1996;28:159

The citations listed below are publications that use Tocris products. Selected citations for PKC (19-36) include:

Showing Results 1 - 1 of 1

  1. Activation of Phosphatidylinositol-Linked Dopamine Receptors Induces a Facilitation of Glutamate-Mediated Synaptic Transmission in the Lateral Entorhinal Cortex.
    Authors: Glovaci and Chapman
    Mol Med Rep
Tocris Peptides
Description Application Cat# Citations Images  

[Glu27]-PKC (19-36)

4059 1  
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