Catalog Number: 4034
Biological Activity
Peptide that reverses the anticoagulant effect of heparin (Cat. No. 2812). Potently binds heparin (Kd = 36 nM in vitro).
Technical Data
  • M.Wt:
    5830
  • Formula:
    C235H425N111O64
  • Sequence:
    AEARARRAAARAARRAKK(AEARARRAAARAARRA)PX(AEARARRAAARAARRA)EN

    (Modifications: Ala-1 = N-terminal Ac, Ala-19 = ε-Ac, X-36 = Dpr, Ala-37 = β-Ac, Glu-53 = C-terminal Amide)

  • Solubility:
    Soluble to 5 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    1234564-95-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license
Background References
  1. Reversal of heparin-induced increases in aPTT in the rat by PM102, a novel heparin antagonist.
    Cushing et al.
    Eur.J.Pharmacol., 2010;635:165
  2. Development of heparin antagonists with focused biological activity.
    Shenoy et al.
    Curr.Pharmaceut.Des., 1999;5:965
Tocris Small Molecules
Description Application Cat# Citations Images  

Heparin sodium salt

2812 3  
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