Competitive NMDA receptor antagonist. Displays Ki
values of 0.84, 2.74, 3.53 and 4.16 μ
M at NR2A, NR2B, NR2C and NR2D subunit-containing receptors respectively. Selective over AMPA receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
The effect of competitive antagonist chain length on NMDA receptor subunit selectivity.
Feng et al.
Cortically evoked excitatory synaptic transmission in the cat red nucleus is antagonised by D-AP5 but not by D-AP7.
Harris and Davies
Brain Res., 1992;594:176