PMPA (NMDA antagonist)

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2273/10
2273/50
PMPA (NMDA antagonist) | CAS No. 113919-36-1 | NMDA Receptor Antagonists
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Description: Competitive NMDA antagonist
Alternative Names: PMPC

Chemical Name: 4-(Phosphonomethyl)-2-piperazinecarboxylic acid

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Biological Activity

Competitive NMDA receptor antagonist. Displays Ki values of 0.84, 2.74, 3.53 and 4.16 μM at GluN2A, GluN2B, GluN2C and GluN2D subunit-containing receptors respectively. Selective over AMPA receptors.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Technical Data

M.Wt:
224.15
Formula:
C6H13N2O5P
Solubility:
Soluble to 100 mM in water
Storage:
Store at +4°C
CAS No:
113919-36-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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