PPPA

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2274/10
2274/50
PPPA | CAS No. 113190-92-4 | NMDA Receptor Antagonists
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Description: Competitive and GluN2A-selective NMDA antagonist
Alternative Names: LY 257883

Chemical Name: (2R*,4S*)-4-(3-Phosphonopropyl)-2-piperidinecarboxylic acid

Product Details
Citations (1)
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Biological Activity

Competitive NMDA receptor antagonist that displays moderate selectivity for NR2A-containing receptors (Ki values are 0.13, 0.47, 1.10 and 3.86 μM for GluN2A, GluN2B, GluN2C and GluN2D subunits respectively).

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Technical Data

M.Wt:
251.22
Formula:
C9H18NO5P
Solubility:
Soluble to 100 mM in water
Storage:
Desiccate at RT
CAS No:
113190-92-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for PPPA

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