PRICKLE1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-81771

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all PRICKLE1 Primary Antibodies »

Product Specifications

Immunogen

PRICKLE1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PRICKLE1. The immunogen is located within the last 50 amino acids of PRICKLE1.

Specificity

Multiple isoforms of PRICKLE1 are known to exist. PRICKLE1 antibody is predicted to not cross-react with other PRICKLE protein family members.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

52, 90 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PRICKLE1 Antibody - BSA Free

PRICKLE1 Antibody - BSA Free

Western Blot: PRICKLE1 Antibody - BSA Free [NBP2-81771] -

Western Blot: PRICKLE1 Antibody - BSA Free [NBP2-81771] - Western blot analysis of PRICKLE1 in human bladder tissue lysate with PRICKLE1 antibody at 1 ug/mL.
PRICKLE1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: PRICKLE1 Antibody - BSA Free [NBP2-81771] -

Immunocytochemistry/ Immunofluorescence: PRICKLE1 Antibody - BSA Free [NBP2-81771] - Immunofluorescence of PRICKLE1 in human bladder cells with PRICKLE1 antibody at 20 ug/mL.

Applications for PRICKLE1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRICKLE1

PRICKLE1 has 831 amino acids and is approximately 94kDa. PRICKLE1 localizes to the nuclear membrane and is involved in the movement of REST, a transcription repressor. PRICKLE1 is implicated in pathways that regulate neural tube development and gastrulation. PRICKLE1 may also be a nuclear receptor that negatively regulates the Wnt/beta-catenin signaling pathway. Current research on PRICKLE1 is being performed in relation to several diseases and disorders including neural tube defects and progressive myoclonic epilepsy type 1B. PRICKLE1 has also been shown to interact with Dishevelled 1, Dishevelled 2, Dishevelled 3, VIP, and SMURF2 in the Wnt signaling pathway.

Alternate Names

EPM1BMGC138902, FLJ31627, FLJ31937, prickle homolog 1 (Drosophila), prickle-like 1, prickle-like 1 (Drosophila), prickle-like protein 1, REST (RE-1 silencing transcription factor)/NRSF (neuron-restrictive silencerfactor)-interacting LIM domain protein, REST/NRSF-interacting LIM domain protein 1, RILPMGC138903

Gene Symbol

PRICKLE1

Additional PRICKLE1 Products

Product Documents for PRICKLE1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for PRICKLE1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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