Prostaglandin E2 Parameter Assay Kit

  (157 citations)
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Product Details
Citations (157)
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  • Assay Length
    3.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (51 uL), Serum (51 uL), EDTA Plasma (51 uL), Heparin Plasma (51 uL), Urine (51 uL)
  • Sensitivity
    41.4 pg/mL
  • Assay Range
    39.0 - 2,500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine)
  • Specificity
    Measures PGE2 levels in various samples
  • Cross-reactivity
    Cross-reactivity observed with 1 or more available related molecules.Cross-species reactivity not tested.
  • Interference
    No significant interference observed with available related molecules.
Control Available
QC142 , Parameter Immunoassay Control Set 777 Human Prostaglandin E2 - Please Inquire
Product Summary
The Parameter PGE2 Immunoassay is a 3.5 hour forward sequential competitive enzyme immunoassay designed to measure PGE2 in cell culture supernates, serum, plasma, and urine.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision
Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 40 40 40
Mean 234 895 1456 253 835 1331
Standard Deviation 21 45 89 33 82 120
CV% 9 5 6.1 12.9 9.9 9

Recovery

The recovery of PGE2 spiked to levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=4) 97 84-106
EDTA Plasma (n=4) 93 82-108
Heparin Plasma (n=4) 94 81-111
Serum (n=4) 97 86-114
Urine (n=4) 99 81-111
Linearity
To assess the linearity of the assay, samples spiked with high concentrations of PGE2 were serially diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
 Prostaglandin E2/PGE2 [Biotin]
Product Datasheets

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Preparation and Storage
  • Storage
    Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Prostaglandin E2/PGE2
Prostaglandin E2 (PGE2) is formed in a variety of cells from prostaglandin H2, which is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. PGE2 has a number of biological actions, including vasodilation, both anti- and proinflammatory action, modulation of sleep/wake cycles, and facilitation of human immunodeficiency virus replication. It elevates cAMP levels, stimulates bone resorption and has thermoregulatory effects. It has been shown to be a regulator of sodium excretion and renal hemodynamics.
  • Alternate Names:
    PGE2
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

157 Citations: Showing 1 - 10
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Species
Sample Type
  1. Three macrophage subsets are identified in the uterus during early human pregnancy
    Authors: X Jiang, MR Du, M Li, H Wang
    Cell. Mol. Immunol., 2018;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  2. Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms
    Authors: JA Ocana, E Romer, R Sahu, SC Pawelzik, GA FitzGerald, MH Kaplan, JB Travers
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  3. Donor-dependent variation of human umbilical cord blood mesenchymal stem cells in response to hypoxic preconditioning and amelioration of limb ischemia
    Authors: I Kang, BC Lee, SW Choi, JY Lee, JJ Kim, BE Kim, DH Kim, SE Lee, N Shin, Y Seo, HS Kim, DI Kim, KS Kang
    Exp. Mol. Med., 2018;50(4):35.
    Species: Human
    Sample Type: Cell Culture Supernates
  4. Anti-inflammatory effect of Tauroursodeoxycholic acid in RAW 264.7 macrophages, Bone marrow-derived macrophages, BV2 microglial cells, and spinal cord injury
    Authors: SJ Kim, WK Ko, MJ Jo, Y Arai, H Choi, H Kumar, IB Han, S Sohn
    Sci Rep, 2018;8(1):3176.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  5. Francisella novicida inhibits spontaneous apoptosis and extends human neutrophil lifespan
    Authors: LC Kinkead, DC Fayram, LH Allen
    J. Leukoc. Biol., 2017;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  6. Protective effect of decursin and decursinol angelate-rich Angelica gigas Nakai extract on dextran sulfate sodium-induced murine ulcerative colitis
    Authors: SR Oh, S Ok, TS Jung, SO Jeon, JM Park, JW Jung, DS Ryu
    Asian Pac J Trop Med, 2017;10(9):864-870.
    Species: Mouse
    Sample Type: Tissue Homogenates
  7. Suppressive Effect of the n-Hexane Extract of Litsea japonica Fruit Flesh on Monosodium-Iodoacetate-Induced Osteoarthritis in Rats
    Authors: SH Kim, HJ Choi, WK Yang, JE Lee, JH Cho, IJ Park, S Park, BK Park, M Jin
    Evid Based Complement Alternat Med, 2017;2017(0):1791403.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  8. Tumor-Derived Mesenchymal Stem Cells Use Distinct Mechanisms to Block the Activity of Natural Killer Cell Subsets
    Authors: S Galland, J Vuille, P Martin, I Letovanec, A Caignard, G Fregni, I Stamenkovi
    Cell Rep, 2017;20(12):2891-2905.
    Species: Human
    Sample Type: Cell Culture Supernates
  9. Use of ethanol extracts of Terminalia chebula to prevent periodontal disease induced by dental plaque bacteria
    Authors: J Lee, YH Nho, SK Yun, YS Hwang
    BMC Complement Altern Med, 2017;17(1):113.
    Species: Human
    Sample Type: Cell Culture Supernates
  10. Cynanchum wilfordii Polysaccharides Suppress Dextran Sulfate Sodium-Induced Acute Colitis in Mice and the Production of Inflammatory Mediators from Macrophages
    Authors: CW Cho, S Ahn, TG Lim, HD Hong, YK Rhee, DC Yang, M Jang
    Mediators Inflamm., 2017;2017(0):3859856.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  11. Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength
    Authors: ATV Ho, AR Palla, MR Blake, ND Yucel, YX Wang, KEG Magnusson, CA Holbrook, PE Kraft, SL Delp, HM Blau
    Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):.
    Species: Mouse
    Sample Type: Tissue Homogenates
  12. Early Gut Microbiota Intervention Suppresses DSS-Induced Inflammatory Responses by Deactivating TLR/NLR Signalling in Pigs
    Authors: Y Xiao, H Yan, H Diao, B Yu, J He, J Yu, P Zheng, X Mao, Y Luo, D Chen
    Sci Rep, 2017;7(1):3224.
    Species: Porcine
    Sample Type: Tissue Culture Supernates
  13. Berbamine Exerts Anti-Inflammatory Effects via Inhibition of NF-?B and MAPK Signaling Pathways
    Authors: XJ Jia, X Li, F Wang, HQ Liu, DJ Zhang, Y Chen
    Cell. Physiol. Biochem., 2017;41(6):2307-2318.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  14. Aronia melanocarpa (Black Chokeberry) Reduces Ethanol-Induced Gastric Damage via Regulation of HSP-70, NF-?B, and MCP-1 Signaling
    Authors: A Paulrayer, A Adithan, JH Lee, KH Moon, DG Kim, SY Im, CW Kang, NS Kim, JH Kim
    Int J Mol Sci, 2017;18(6):.
    Species: Rat
    Sample Type: Tissue Homogenates
  15. Black soybean anthocyanins attenuate inflammatory responses by suppressing reactive oxygen species production and mitogen activated protein kinases signaling in lipopolysaccharide-stimulated macrophages
    Authors: JN Kim, SN Han, TJ Ha, HK Kim
    Nutr Res Pract, 2017;11(5):357-364.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  16. Resolvin D1 Improves the Resolution of Inflammation via Activating NF-?B p50/p50-Mediated Cyclooxygenase-2 Expression in Acute Respiratory Distress Syndrome
    Authors: Y Gao, H Zhang, L Luo, J Lin, D Li, S Zheng, H Huang, S Yan, J Yang, Y Hao, H Li, F Gao Smith, S Jin
    J. Immunol., 2017;0(0):.
  17. 3'-Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis
    Authors: J Jeon, LJ Kang, KM Lee, C Cho, EK Song, W Kim, TJ Park, S Yang
    J. Cell. Mol. Med., 2017;0(0):.
    Species: Mouse
    Sample Type: Cell Lysates
  18. Kaempferol Alleviates the Interleukin-1?-Induced Inflammation in Rat Osteoarthritis Chondrocytes via Suppression of NF-?B
    Authors: Z Zhuang, G Ye, B Huang
    Med. Sci. Monit., 2017;23(0):3925-3931.
    Species: Rat
    Sample Type: Cell Culture Supernates
  19. Adipose-derived mesenchymal stem cells modulate CD14(++)CD16(+) expression on monocytes from sepsis patients in vitro via prostaglandin E2
    Authors: G Qiu, G Zheng, M Ge, L Huang, H Tong, P Chen, D Lai, Y Hu, B Cheng, Q Shu, J Xu
    Stem Cell Res Ther, 2017;8(1):97.
    Species: Humab
    Sample Type: Cell Culture Supernates
  20. IL-33 promotes colon cancer cell stemness via JNK activation and macrophage recruitment
    Authors: M Fang, Y Li, K Huang, S Qi, J Zhang, W Zgodzinski, M Majewski, G Wallner, S Gozdz, P Macek, A Kowalik, M Pasiarski, E Grywalska, L Vatan, N Nagarsheth, W Li, L Zhao, I Kryczek, G Wang, Z Wang, W Zou, L Wang
    Cancer Res, 2017;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  21. Cheongsangbangpung-tang ameliorated the acute inflammatory response via the inhibition of NF-?B activation and MAPK phosphorylation
    Authors: SY Kim, SM Park, M Hwangbo, JR Lee, SH Byun, SK Ku, IJ Cho, SC Kim, SY Jee, SJ Park
    BMC Complement Altern Med, 2017;17(1):46.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  22. Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation
    Authors: A Sapkota, BP Gaire, KS Cho, SJ Jeon, OW Kwon, DS Jang, SY Kim, JH Ryu, JW Choi
    PLoS ONE, 2017;12(2):e0171479.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  23. Stellera chamaejasme and its constituents induce cutaneous wound healing and anti-inflammatory activities
    Authors: M Kim, HJ Lee, A Randy, JH Yun, SR Oh, CW Nho
    Sci Rep, 2017;7(0):42490.
    Species: Human
    Sample Type: Cell Culture Supernates
  24. Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate?induced osteoarthritis rats
    Authors: JW Jeong, HH Lee, J Kim, EO Choi, H Hwang-Bo, HJ Kim, MY Kim, KI Ahn, GY Kim, KW Lee, KY Kim, SG Kim, SH Hong, C Park, HJ Cha, YH Choi
    Mol Med Rep, 2017;0(0):.
    Species: Rat
    Sample Type: Serum
  25. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
    Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He
    Autophagy, 2017;0(0):0.
    Species: Mouse
    Sample Type: Tissue Homogenates
  26. Therapeutic effects of lornoxicam-loaded nanomicellar formula in experimental models of rheumatoid arthritis
    Authors: HS Helmy, AE El-Sahar, RH Sayed, RN Shamma, AH Salama, EM Elbaz
    Int J Nanomedicine, 2017;12(0):7015-7023.
    Species: Rat
    Sample Type: Serum
  27. Anti-inflammatory coumarins from Paramignya trimera
    Authors: HL Tuan Anh, DC Kim, W Ko, TM Ha, NX Nhiem, PH Yen, BH Tai, LH Truong, VN Long, T Gioi, T Hong Quang, CV Minh, H Oh, YC Kim, PV Kiem
    Pharm Biol, 2017;55(1):1195-1201.
    Species: Mouse
    Sample Type: Cell Culture Supenates
  28. Toward understanding the role of cartilage particulates in synovial inflammation
    Authors: AM Silverstei, RM Stefani, E Sobczak, EL Tong, MG Attur, RP Shah, JC Bulinski, GA Ateshian, CT Hung
    Osteoarthr. Cartil., 2017;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  29. Anti-inflammatory effects of novel polygonum multiflorum compound via inhibiting NF-?B/MAPK and upregulating the Nrf2 pathways in LPS-stimulated microglia
    Authors: SY Park, ML Jin, NJ Kang, G Park, YW Choi
    Neurosci. Lett., 2017;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  30. Leaves of Raphanus sativus L. Shows Anti-Inflammatory Activity in LPS-Stimulated Macrophages via Suppression of COX-2 and iNOS Expression
    Authors: HJ Park, M Song
    Prev Nutr Food Sci, 2017;22(1):50-55.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  31. Asperflavin, an Anti-Inflammatory Compound Produced by a Marine-Derived Fungus, Eurotium amstelodami
    Authors: X Yang, MC Kang, Y Li, EA Kim, SM Kang, YJ Jeon
    Molecules, 2017;22(11):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  32. Prolonged inhibition of inflammation in osteoarthritis by triamcinolone acetonide released from a polyester amide microsphere platform
    Authors: I Rudnik-Jan, S Colen, J Berard, S Plomp, I Que, M van Rijen, N Woike, A Egas, G van Osch, E van Maarse, K Messier, A Chan, J Thies, L Creemers
    J Control Release, 2017;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  33. Pro-inflammatory M1 macrophages promote osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway
    Authors: LY Lu, F Loi, K Nathan, TH Lin, J Pajarinen, E Gibon, A Nabeshima, L Cordova, E Jämsen, Z Yao, SB Goodman
    J. Orthop. Res, 2017;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  34. Equol, a Dietary Daidzein Gut Metabolite Attenuates Microglial Activation and Potentiates Neuroprotection In Vitro
    Authors: L Subedi, E Ji, D Shin, J Jin, JH Yeo, SY Kim
    Nutrients, 2017;9(3):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  35. Evaluation of an Aqueous Extract from Horseradish Root (Armoracia rusticana Radix) against Lipopolysaccharide-Induced Cellular Inflammation Reaction
    Authors: C Herz, HT Tran, MR Márton, R Maul, S Baldermann, M Schreiner, E Lamy
    Evid Based Complement Alternat Med, 2017;2017(0):1950692.
    Species: Human
    Sample Type: Cell Culture Supernates
  36. Pro-inflammatory Signaling in a 3D Organotypic Skin Model after Low LET Irradiation-NF-?B, COX-2 Activation, and Impact on Cell Differentiation
    Authors: A Acheva, G Schettino, KM Prise
    Front Immunol, 2017;8(0):82.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  37. Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis
    Authors: T Lin, J Pajarinen, A Nabeshima, L Lu, K Nathan, E Jämsen, Z Yao, SB Goodman
    Stem Cell Res Ther, 2017;8(1):277.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  38. Chemotherapy induces ovarian cancer cell repopulation through the caspase 3-mediated arachidonic acid metabolic pathway
    Authors: L Cui, Y Zhao, Y Pan, X Zheng, D Shao, Y Jia, K He, K Li, L Chen
    Onco Targets Ther, 2017;10(0):5817-5826.
    Species: Human
    Sample Type: Cell Culture Supernates
  39. Saikosaponin A inhibits IL-1?-induced inflammatory mediators in human osteoarthritis chondrocytes by activating LXR?
    Authors: H Gao, Y Song, D Li, W Feng, J Liu
    Oncotarget, 2017;8(51):88941-88950.
    Species: Human
    Sample Type: Cell Culture Supernates
  40. N,N-disubstituted azines attenuate LPS-mediated neuroinflammation in microglia and neuronal apoptosis via inhibiting MAPK signaling pathways
    Authors: L Subedi, OW Kwon, C Pak, G Lee, K Lee, H Kim, SY Kim
    BMC Neurosci, 2017;18(1):82.
    Species: Human
    Sample Type: Cell Culture Supernates
  41. Tussilagone Inhibits the Inflammatory Response and Improves Survival in CLP-Induced Septic Mice
    Authors: YK Kim, MG Yeo, BK Oh, HY Kim, HJ Yang, SS Cho, M Gil, KJ Lee
    Int J Mol Sci, 2017;18(12):.
    Species: Mouse
    Sample Type: Serum
  42. YAP1 and COX2 coordinately regulate urothelial cancer stem-like cells
    Authors: A Ooki, M Del Carmen, L Marchionni, W Dinalankar, A Begum, NM Hahn, CJ VandenBuss, ZA Rasheed, S Mao, GJ Netto, D Sidransky, MO Hoque
    Cancer Res., 2017;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  43. Silibinin protects against osteoarthritis through inhibiting the inflammatory response and cartilage matrix degradation in vitro and in vivo
    Authors: W Zheng, Z Feng, Y Lou, C Chen, C Zhang, Z Tao, H Li, L Cheng, X Ying
    Oncotarget, 2017;8(59):99649-99665.
    Species: Human
    Sample Type: Cell Culture Supernates
  44. Copper oxide nanoparticles recruit macrophages and modulate nitric oxide, proinflammatory cytokines and PGE2 production through arginase activation
    Authors: S Arancibia, A Barrientos, J Torrejón, A Escobar, CJ Beltrán
    Nanomedicine (Lond), 2016;0(0):.
    Species: Mouse
    Sample Type: Cell Lysates
  45. Stromal fibroblasts support dendritic cells to maintain IL-23/Th17 responses after exposure to ionizing radiation
    Authors: A Malecka, Q Wang, S Shah, RV Sutavani, I Spendlove, JM Ramage, J Greensmith, HA Franks, MJ Gough, A Saalbach, PM Patel, AM Jackson
    J Leukoc Biol, 2016;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  46. Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation
    Sci Rep, 2016;6(0):30263.
    Species: Human
    Sample Type: Cell Culture Supernates
  47. Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts
    Authors: Chan-Mi Lee
    Cell Biosci, 2016;6(0):43.
    Species: Human
    Sample Type: Cell Culture Supernates
  48. Anti-Inflammatory Effects of Agrimoniin-Enriched Fractions of Potentilla erecta
    Authors: Julia Hoffmann
    Molecules, 2016;21(6):.
    Species: Human
    Sample Type: Cell Culture Supernates
  49. Human Liver Stem Cells Suppress T-Cell Proliferation, NK Activity, and Dendritic Cell Differentiation
    Authors: S Bruno, C Grange, M Tapparo, C Pasquino, R Romagnoli, E Dametto, A Amoroso, C Tetta, G Camussi
    Stem Cells Int, 2016;2016(0):8468549.
    Species: Human
    Sample Type: Cell Culture Supernates
  50. Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus Aspergillus sp. SF-6354 via up-Regulation of Heme Oxygenase-1 in Murine Hippocampal and Microglial Cell Lines
    Authors: DC Kim, KH Cho, W Ko, CS Yoon, JH Sohn, JH Yim, YC Kim, H Oh
    Int J Mol Sci, 2016;17(4):.
    Species: Mouse
    Sample Type: Cell Lysates
  51. The role of extracellular vesicle and tunneling nanotube-mediated intercellular cross-talk between mesenchymal stem cells and human peripheral T cells
    Stem Cells Dev, 2016;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  52. mRNA expression pattern of selected candidate genes differs in bovine oviductal epithelial cells in vitro compared with the in vivo state and during cell culture passages
    Authors: S Danesh Mes, J Sharbati, R Einspanier, C Gabler
    Reprod. Biol. Endocrinol, 2016;14(1):44.
    Species: Bovine
    Sample Type: Cell Culture Supernates
  53. 24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats
    PLoS ONE, 2016;11(8):e0161782.
    Species: Rat
    Sample Type: Cell Culture Supernates
  54. Indoleamine 2,3-Dioxygenase Is Not a Pivotal Regulator Responsible for Suppressing Allergic Airway Inflammation through Adipose-Derived Stem Cells
    PLoS ONE, 2016;11(11):e0165661.
    Species: Mouse
    Sample Type: Serum
  55. Topical Treatment With Bromfenac Reduces Retinal Gliosis and Inflammation After Optic Nerve Crush
    Invest. Ophthalmol. Vis. Sci., 2016;57(14):6098-6106.
    Species: Rat
    Sample Type: Tissue Homogenates
  56. Chondrocyte-derived extracellular matrix suppresses pathogenesis of human pterygium epithelial cells by blocking the NF-?B signaling pathways
    Authors: H Lee, M Lee, Y Lee, S Choi, J Yang
    Mol. Vis, 2016;22(0):1490-1502.
    Species: Human
    Sample Type: Cell Culture Supernates
  57. Human Mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE2-dependent mechanism
    Sci Rep, 2016;6(0):38308.
    Species: Human
    Sample Type: Cell Culture Supernates
  58. The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection
    PLoS ONE, 2016;11(12):e0168102.
    Species: Human
    Sample Type: Cell Culture Supernates
  59. Prostaglandin E2, trace elements and levels of oxidative processes in spontaneous miscarriages
    Eur Rev Med Pharmacol Sci, 2016;20(22):4786-4790.
    Species: Human
    Sample Type: Plasma
  60. Anti-Neuroinflammatory ent-Kaurane Diterpenoids from Pteris multifida Roots
    Molecules, 2016;22(1):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  61. MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis
    Proc. Natl. Acad. Sci. U.S.A., 2016;113(49):E7917-E7926.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  62. Controlled Release of Interleukin-1 Receptor Antagonist from Hyaluronic Acid-Chitosan Microspheres Attenuates Interleukin-1?-Induced Inflammation and Apoptosis in Chondrocytes
    Biomed Res Int, 2016;2016(0):6290957.
    Species: Rat
    Sample Type: Cell Culture Supernates
  63. Acupuncture ameliorates inflammatory response in a chronic unpredictable stress rat model of depression
    Authors: Jun Lu
    Brain Res. Bull, 2016;0(0):.
    Species: Rat
    Sample Type: Tissue Lysates
  64. Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells.
    Authors: Lee S, Yi J, Bae W, Lee S, Cha H, Kim E
    PLoS ONE, 2016;11(1):e0146708.
    Species: Human
    Sample Type: Cell Culture Supernates
  65. Fucoidan inhibits LPS-induced inflammation in vitro and during the acute response in vivo
    Authors: Jisang Park
    Int. Immunopharmacol, 2016;43(0):91-98.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  66. Anti-inflammatory effect of tricin isolated from Alopecurus aequalis Sobol. on the LPS-induced inflammatory response in RAW 264.7 cells
    Authors: Byoung-Man Kang
    Int. J. Mol. Med, 2016;38(5):1614-1620.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  67. The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2.
    Sci Rep, 2015;5(0):8713.
    Species: Rat
    Sample Type: Serum
  68. Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment.
    Authors: Li P, Shan J, Chen X, Zhang D, Su L, Huang X, Yu B, Zhi Q, Li C, Wang Y, Tomei S, Cai Q, Ji J, Li J, Chouchane L, Yu Y, Sun F, Xu Z, Liu B, Zhu Z
    Cell Res, 2015;25(5):588-603.
    Species: Human
    Sample Type: Cell Culture Supernates
  69. Crotoxin from Crotalus durissus terrificus is able to down-modulate the acute intestinal inflammation in mice.
    Authors: Almeida C, Andrade-Oliveira V, Camara N, Jacysyn J, Faquim-Mauro E
    PLoS ONE, 2015;10(4):e0121427.
    Species: Mouse
    Sample Type: Tissue Homogenates
  70. Impaired Expression of Prostaglandin E2 (PGE2) Synthesis and Degradation Enzymes during Differentiation of Immortalized Urothelial Cells from Patients with Interstitial Cystitis/Painful Bladder Syndrome.
    Authors: Marentette J, Hurst R, McHowat J
    PLoS ONE, 2015;10(6):e0129466.
    Species: Human
    Sample Type: Cell Culture Supernates
  71. Diosmin protects against ethanol-induced gastric injury in rats: novel anti-ulcer actions.
    Authors: Arab H, Salama S, Omar H, Arafa E, Maghrabi I
    PLoS ONE, 2015;10(3):e0122417.
    Species: Rat
    Sample Type: Tissue Homogenates
  72. Mesenchymal stem cells alleviate airway inflammation and emphysema in COPD through down-regulation of cyclooxygenase-2 via p38 and ERK MAPK pathways.
    Authors: Gu, Wen, Song, Lin, Li, Xiao-Min, Wang, Di, Guo, Xue-Jun, Xu, Wei-Guo
    Sci Rep, 2015;5(0):8733.
    Species: Rat
    Sample Type: BALF
  73. Development of an equine groove model to induce metacarpophalangeal osteoarthritis: a pilot study on 6 horses.
    Authors: Maninchedda U, Lepage O, Gangl M, Hilairet S, Remandet B, Meot F, Penarier G, Segard E, Cortez P, Jorgensen C, Steinberg R
    PLoS ONE, 2015;10(2):e0115089.
    Species: Equine
    Sample Type: Synovial Fluid
  74. Ex Vivo Induced Regulatory Human/Murine Mesenchymal Stem Cells as Immune Modulators.
    Authors: Hinden L, Shainer R, Almogi-Hazan O, Or R
    Stem Cells, 2015;33(7):2256-67.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  75. Dose-response of superparamagnetic iron oxide labeling on mesenchymal stem cells chondrogenic differentiation: a multi-scale in vitro study.
    Authors: Roeder E, Henrionnet C, Goebel J, Gambier N, Beuf O, Grenier D, Chen B, Vuissoz P, Gillet P, Pinzano A
    PLoS ONE, 2014;9(5):e98451.
    Species: Human
    Sample Type: Cell Culture Supernates
  76. Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma.
    Authors: Sidney L, Kirkham G, Buttery L
    Stem Cells Dev, 2014;23(6):605-17.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  77. Liver myofibroblasts up-regulate monocyte CD163 expression via PGE2 during hepatitis B induced liver failure.
    Authors: Zhang M, Ye Y, Wang F, Zhu J, Zhao Q, Zheng Y, Gu Y, Xie C, Huang Z, Tai Q, Chong Y, Gao Z
    , 2014;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  78. Equine mesenchymal stem cells inhibit T cell proliferation through different mechanisms depending on tissue source.
    Authors: Carrade Holt D, Wood J, Granick J, Walker N, Clark K, Borjesson D
    Stem Cells Dev, 2014;23(11):1258-65.
    Species: Equine
    Sample Type: Cell Culture Supernates
  79. Lysosomal phospholipase A2: a novel player in host immunity to Mycobacterium tuberculosis.
    Authors: Schneider B, Behrends J, Hagens K, Harmel N, Shayman J, Schaible U
    Eur J Immunol, 2014;44(8):2394-404.
    Species: Mouse
    Sample Type: Tissue Homogenates
  80. Leishmanial lipid suppresses the bacterial endotoxin-induced inflammatory response with attenuation of tissue injury in sepsis.
    Authors: Chatterjee N, Das S, Bose D, Banerjee S, Jha T, Saha K
    J Leukoc Biol, 2014;96(2):325-36.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  81. A pilot study investigating early postoperative changes of plasma polyunsaturated fatty acids after laparoscopic sleeve gastrectomy.
    Authors: Aslan M, Aslan I, Ozcan F, Eryilmaz R, Ensari C, Bilecik T
    Lipids Health Dis, 2014;13(0):62.
    Species: Human
    Sample Type: Serum
  82. Rapamycin inhibits Toll-like receptor 4-induced pro-oncogenic function in head and neck squamous cell carcinoma.
    Authors: Ren G, Hu J, Wang R, Han W, Zhao M, Zhou G, Zhang C, Zhang Z
    Oncol Rep, 2014;31(6):2804-10.
    Species: Human
    Sample Type: Cell Culture Supernates
  83. TREM-1 is induced in tumor associated macrophages by cyclo-oxygenase pathway in human non-small cell lung cancer.
    Authors: Yuan, Zhihong, Mehta, Hiren J, Mohammed, Kamal, Nasreen, Najmunis, Roman, Robert, Brantly, Mark, Sadikot, Ruxana T
    PLoS ONE, 2014;9(5):e94241.
    Species: Human
    Sample Type: Tissue Homogenates
  84. Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1.
    Authors: Annamanedi M, Kalle A
    PLoS ONE, 2014;9(6):e99285.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  85. Telmisartan attenuates colon inflammation, oxidative perturbations and apoptosis in a rat model of experimental inflammatory bowel disease.
    Authors: Arab H, Al-Shorbagy M, Abdallah D, Nassar N
    PLoS ONE, 2014;9(5):e97193.
    Species: Rat
    Sample Type: Tissue Homogenates
  86. Effect of thrombin on human amnion mesenchymal cells, mouse fetal membranes, and preterm birth.
    Authors: Mogami, Haruta, Keller, Patrick, Shi, Haolin, Word, R Ann
    J Biol Chem, 2014;289(19):13295-307.
    Species: Human
    Sample Type: Cell Culture Supernates
  87. From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract.
    Authors: Ebeling, Sandra, Naumann, Katrin, Pollok, Simone, Wardecki, Tina, Vidal-Y-Sy, Sabine, Nascimento, Juliana, Boerries, Melanie, Schmidt, Gudula, Brandner, Johanna, Merfort, Irmgard
    PLoS ONE, 2014;9(1):e86147.
    Species: Human
    Sample Type: Cell Culture Supernates
  88. A p38 MAPK-mediated alteration of COX-2/PGE2 regulates immunomodulatory properties in human mesenchymal stem cell aging.
    Authors: Yu K, Lee J, Kim H, Hong I, Choi S, Seo Y, Kang I, Kim J, Lee B, Lee S, Kurtz A, Seo K, Kang K
    PLoS ONE, 2014;9(8):e102426.
    Species: Human
    Sample Type: Cell Culture Supernates
  89. Inhibitory effects of benzaldehyde derivatives from the marine fungus Eurotium sp. SF-5989 on inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages.
    Authors: Kim K, Cui X, Lee D, Ko W, Sohn J, Yim J, An R, Kim Y, Oh H
    Int J Mol Sci, 2014;15(12):23749-65.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  90. Pheophytin a inhibits inflammation via suppression of LPS-induced nitric oxide synthase-2, prostaglandin E2, and interleukin-1beta of macrophages.
    Authors: Lin C, Lee C, Chang Y, Wang H, Chen C, Chen Y
    Int J Mol Sci, 2014;15(12):22819-34.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  91. Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression.
    Authors: Chen C, Akiyama K, Yamaza T, You Y, Xu X, Li B, Zhao Y, Shi S
    EMBO Mol Med, 2014;6(3):322-34.
    Species: Human
    Sample Type: Cell Culture Supernates
  92. Liver myofibroblasts from hepatitis B related liver failure patients may regulate natural killer cell function via PGE2.
    Authors: Zhang, Min, Wang, Fenglan, Chong, Yutian, Tai, Qiang, Zhao, Qiyi, Zheng, Yubao, Peng, Liang, Lin, Shumei, Gao, Zhiliang
    J Transl Med, 2014;12(1):308.
    Species: Human
    Sample Type: Cell Culture Supernates
  93. Regulated expression of PTPRJ by COX-2/PGE2 axis in endothelial cells.
    Authors: Xu X, Lan W, Jin X, Wang B, Yan H, Chen X, Lai X, Zhang L, Zhang X, Li Z
    PLoS ONE, 2014;9(12):e114996.
    Species: Human
    Sample Type: Cell Culture Supernates
  94. NSAID use reduces breast cancer recurrence in overweight and obese women: role of prostaglandin-aromatase interactions.
    Authors: Bowers L, Maximo I, Brenner A, Beeram M, Hursting S, Price R, Tekmal R, Jolly C, deGraffenried L
    Cancer Res, 2014;74(16):4446-57.
    Species: Human
    Sample Type: Cell Culture Supernates
  95. Endogenous omega-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice.
    Authors: Li J, Li F, Wei D, Jia W, Kang J, Stefanovic-Racic M, Dai Y, Zhao A
    Mol Endocrinol, 2014;28(8):1316-28.
    Species: Mouse
    Sample Type: Serum
  96. Interference of Ca(2)(+) with the proliferation of SCCOHT-1 and ovarian adenocarcinoma cells.
    Authors: Otte A, Rauprich F, von der Ohe J, Hillemanns P, Hass R
    Int J Oncol, 2014;45(3):1151-8.
    Species: Human
    Sample Type: Cell Culture Supernates
  97. Tensile strain increased COX-2 expression and PGE2 release leading to weakening of the human amniotic membrane.
    Authors: Chowdhury B, David A, Thrasivoulou C, Becker D, Bader D, Chowdhury T
    Placenta, 2014;35(12):1057-64.
    Species: Human
    Sample Type: Cell Culture Supernates
  98. Comparison of angiogenic, cytoprotective, and immunosuppressive properties of human amnion- and chorion-derived mesenchymal stem cells.
    Authors: Yamahara, Kenichi, Harada, Kazuhiko, Ohshima, Makiko, Ishikane, Shin, Ohnishi, Shunsuke, Tsuda, Hidetosh, Otani, Kentaro, Taguchi, Akihiko, Soma, Toshihir, Ogawa, Hiroyasu, Katsuragi, Shinji, Yoshimatsu, Jun, Harada-Shiba, Mariko, Kangawa, Kenji, Ikeda, Tomoaki
    PLoS ONE, 2014;9(2):e88319.
    Species: Human
    Sample Type: Cell Culture Supernates
  99. Vaccine-induced myeloid cell population dampens protective immunity to SIV.
    Authors: Sui Y, Hogg A, Wang Y, Frey B, Yu H, Xia Z, Venzon D, McKinnon K, Smedley J, Gathuka M, Klinman D, Keele B, Langermann S, Liu L, Franchini G, Berzofsky J
    J Clin Invest, 2014;124(6):2538-49.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Plasma
  100. Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
    Authors: Dang, Shipeng, Xu, Huanbai, Xu, Congfeng, Cai, Wei, Li, Qian, Cheng, Yiji, Jin, Min, Wang, Ru-Xing, Peng, Yongde, Zhang, Yi, Wu, Changpin, He, Xiaozhou, Wan, Bing, Zhang, Yanyun
    Autophagy, 2014;10(7):1301-15.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  101. Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation.
    Authors: Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, Wang Q, Cao X
    J Biol Chem, 2014;289(16):11522-35.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  102. Anti-inflammatory effects of Perilla frutescens leaf extract on lipopolysaccharide-stimulated RAW264.7 cells.
    Authors: Huang B, Lin C, Chen Y, Kao S
    Mol Med Rep, 2014;10(2):1077-83.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  103. Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts.
    Authors: Delaine-Smith, Robin M, Sittichokechaiwut, Anuphan, Reilly, Gwendole
    FASEB J, 2014;28(1):430-9.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  104. Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner.
    Authors: Mace T, Ameen Z, Collins A, Wojcik S, Mair M, Young G, Fuchs J, Eubank T, Frankel W, Bekaii-Saab T, Bloomston M, Lesinski G
    Cancer Res, 2014;73(10):3007-18.
    Species: Human
    Sample Type: Cell Culture Supernates
  105. MicroRNA-146a negatively regulates the immunoregulatory activity of bone marrow stem cells by targeting prostaglandin E2 synthase-2.
    Authors: Matysiak, Mariola, Fortak-Michalska, Maria, Szymanska, Bozena, Orlowski, Wojciech, Jurewicz, Anna, Selmaj, Krzyszto
    J Immunol, 2013;190(10):5102-9.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  106. Sex difference in urocortin production is contributory to the gender disparity in a rat model of vasculitis induced by sodium laurate.
    Authors: Wan, Rong, Jin, Lai, Zhu, Chao, Liu, Yunxin, Li, Li, Guo, Rui, Li, Shengnan
    Endocrinology, 2013;154(12):4663-74.
    Species: Rat
    Sample Type: Plasma
  107. LC-MS/MS analysis of plasma polyunsaturated fatty acids in type 2 diabetic patients after insulin analog initiation therapy.
    Authors: Aslan M, Ozcan F, Aslan I, Yucel G
    Lipids Health Dis, 2013;12(0):169.
    Species: Human
    Sample Type: Serum
  108. Madecassoside inhibits melanin synthesis by blocking ultraviolet-induced inflammation.
    Authors: Jung, Eunsun, Lee, Jung-A, Shin, Seoungwo, Roh, Kyung-Ba, Kim, Jang-Hyu, Park, Deokhoon
    Molecules, 2013;18(12):15724-36.
    Species: Human
    Sample Type: Cell Culture Supernates
  109. Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic leukemia.
    Authors: Conforti A, Biagini S, Del Bufalo F, Sirleto P, Angioni A, Starc N, Li Pira G, Moretta F, Proia A, Contoli B, Genovese S, Ciardi C, Avanzini M, Rosti V, Lo-Coco F, Locatelli F, Bernardo M
    PLoS ONE, 2013;8(11):e76989.
    Species: Human
    Sample Type: Cell Culture Supernates
  110. Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice.
    Authors: Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R
    J Biol Chem, 2013;288(3):1953-66.
    Species: Human
    Sample Type: Cell Culture Supernates
  111. Diterpenylquinone hybrids: synthesis and assessment of gastroprotective mechanisms of action in human cells.
    Authors: Theoduloz, Cristina, Bravo, Ivanna, Pertino, Mariano, Schmeda-Hirschmann, Guillerm
    Molecules, 2013;18(9):11044-66.
    Species: Human
    Sample Type: Cell Culture Supernates
  112. Antagonizing effects and mechanisms of afzelin against UVB-induced cell damage.
    Authors: Shin S, Jung E, Kim S, Kim J, Kim E, Lee J, Park D
    PLoS ONE, 2013;8(4):e61971.
    Species: Human
    Sample Type: Cell Culture Supernates
  113. Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells.
    Authors: Iachininoto M, Nuzzolo E, Bonanno G, Mariotti A, Procoli A, Locatelli F, De Cristofaro R, Rutella S
    Molecules, 2013;18(9):10132-45.
    Species: Human
    Sample Type: Cell Culture Supernates
  114. Adipose-derived mesenchymal stem cells exert antiinflammatory effects on chondrocytes and synoviocytes from osteoarthritis patients through prostaglandin E2.
    Authors: Manferdini C, Maumus M, Gabusi E, Piacentini A, Filardo G, Peyrafitte J, Jorgensen C, Bourin P, Fleury-Cappellesso S, Facchini A, Noel D, Lisignoli G
    Arthritis Rheum, 2013;65(5):1271-81.
    Species: Human
    Sample Type: Cell Culture Supernates
  115. AMPK in the small intestine in normal and pathophysiological conditions.
    Authors: Harmel E, Grenier E, Bendjoudi Ouadda A, El Chebly M, Ziv E, Beaulieu J, Sane A, Spahis S, Laville M, Levy E
    Endocrinology, 2013;155(3):873-88.
    Species: Rat
    Sample Type: Tissue Homogenates
  116. Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling.
    Authors: Liu L, Cao Z, Chen J
    J. Biol. Chem., 2012;287(15):11899-910.
    Species: Human
    Sample Type: Serum
  117. Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.
    Authors: Wang JH, Shih KS, Liou JP, Wu YW, Chang AS, Wang KL, Tsai CL, Yang CR
    PLoS ONE, 2012;7(2):e31368.
    Species: Human
    Sample Type: Cell Culture Supernates
  118. Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
    Authors: Gottfries J, Melgar S, Michaelsson E
    PLoS ONE, 2012;7(1):e30005.
    Species: Mouse
    Sample Type: Tissue Homogenates
  119. Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.
    Authors: Ylostalo J, Bartosh T, Coble K, Prockop D
    Stem Cells, 2012;30(10):2283-96.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  120. Role of the tumor suppressor ARF in macrophage polarization: Enhancement of the M2 phenotype in ARF-deficient mice.
    Authors: Herranz S, Traves P, Luque A, Hortelano S
    Oncoimmunology, 2012;1(8):1227-1238.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  121. Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells.
    Authors: Zong Y, Sun L, Liu B, Deng Y, Zhan D, Chen Y, He Y, Liu J, Zhang Z, Sun J, Lu D
    PLoS ONE, 2012;7(8):e44107.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  122. Mesenchymal stem cells expanded in human platelet lysate display a decreased inhibitory capacity on T- and NK-cell proliferation and function.
    Authors: Abdelrazik H, Spaggiari GM, Chiossone L, Moretta L
    Eur. J. Immunol., 2011;41(11):3281-90.
    Species: Human
    Sample Type: Cell Culture Supernates
  123. Inhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell death.
    Authors: Zhao Z, Liu N, Huang J, Lu PH, Xu XM
    J. Neurochem., 2011;116(6):1057-65.
    Species: Rat
    Sample Type: Cell Culture Supernates
  124. Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes.
    Authors: Verma S, Kumar M, Nerurkar VR
    J. Gen. Virol., 2011;92(0):507-15.
    Species: Human
    Sample Type: Cell Culture Supernates
  125. Evidence for regulated interleukin-4 expression in chondrocyte-scaffolds under in vitro inflammatory conditions.
    Authors: Rai MF, Graeve T, Twardziok S, Schmidt MF
    PLoS ONE, 2011;6(10):e25749.
    Species: Canine
    Sample Type: Cell Culture Supernates
  126. Serotonin activates dendritic cell function in the context of gut inflammation.
    Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
    Am. J. Pathol., 2011;178(2):662-71.
    Species: Mouse
    Sample Type: Tissue Homogenates
  127. Deconstructing tick saliva: non-protein molecules with potent immunomodulatory properties.
    Authors: Oliveira CJ, Sa-Nunes A, Francischetti IM, Carregaro V, Anatriello E, Silva JS, Santos IK, Ribeiro JM, Ferreira BR
    J. Biol. Chem., 2011;286(13):10960-9.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  128. Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1-/- mice.
    Authors: Niwa S, Urtz N, Baumruker T, Billich A, Bornancin F
    Lipids Health Dis, 2010;9(0):1.
    Species: Mouse
    Sample Type: BALF
  129. Prostaglandin I2-IP signaling promotes Th1 differentiation in a mouse model of contact hypersensitivity.
    Authors: Nakajima S, Honda T, Sakata D, Egawa G, Tanizaki H, Otsuka A, Moniaga CS, Watanabe T, Miyachi Y, Narumiya S, Kabashima K
    J. Immunol., 2010;184(10):5595-603.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  130. Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms.
    Authors: Rydkina E, Turpin LC, Sahni SK
    Infect. Immun., 2010;78(6):2599-606.
    Species: Human
    Sample Type: Cell Culture Supernates
  131. P2Y2 receptor transcription is increased by NF-kappa B and stimulates cyclooxygenase-2 expression and PGE2 released by intestinal epithelial cells.
    Authors: Degagne E, Grbic DM, Dupuis AA, Lavoie EG, Langlois C, Jain N, Weisman GA, Sevigny J, Gendron FP
    J. Immunol., 2009;183(7):4521-9.
    Species: Human
    Sample Type: Cell Culture Supernates
  132. Therapeutic effect of Aralia cordata extracts on cartilage protection in collagenase-induced inflammatory arthritis rabbit model.
    Authors: Park DS, Huh JE, Baek YH
    J Ethnopharmacol, 2009;125(2):207-17.
    Species: Rabbit
    Sample Type: Serum
  133. Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming.
    Authors: Highfill SL, Kelly RM, O'Shaughnessy MJ, Zhou Q, Xia L, Panoskaltsis-Mortari A, Taylor PA, Tolar J, Blazar BR
    Blood, 2009;114(3):693-701.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  134. In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat pituitary gland.
    Authors: Sanchez-Lemus E, Benicky J, Pavel J, Saavedra JM
    Brain Behav. Immun., 2009;23(7):945-57.
    Species: Rat
    Sample Type: Tissue Homogenates
  135. Extracellular release of ATP mediated by cyclic mechanical stress leads to mobilization of AA in trabecular meshwork cells.
    Authors: Luna C, Li G, Qiu J, Challa P, Epstein DL, Gonzalez P
    Invest. Ophthalmol. Vis. Sci., 2009;50(12):5805-10.
    Species: Porcine
    Sample Type: Cell Culture Supernates
  136. Fra-1/AP-1 impairs inflammatory responses and chondrogenesis in fracture healing.
    Authors: Yamaguchi T, Takada Y, Maruyama K, Shimoda K, Arai Y, Nango N, Kosaki N, Takaishi H, Toyama Y, Matsuo K
    J. Bone Miner. Res., 2009;24(12):2056-65.
    Species: Mouse
    Sample Type: Serum
  137. In vitro and in vivo anti-Helicobacter pylori activity of Calophyllum brasiliense Camb.
    Authors: Souza Mdo C, Beserra AM, Martins DC, Real VV, Santos RA, Rao VS, Silva RM, Martins DT
    J Ethnopharmacol, 2009;123(3):452-8.
    Species: Rat
    Sample Type: Tissue Homogenates
  138. Arachidonic acid potentiates hypoxia-induced VEGF expression in mouse embryonic stem cells: involvement of Notch, Wnt, and HIF-1alpha.
    Authors: Lee SH, Kim MH, Han HJ
    Am. J. Physiol., Cell Physiol., 2009;297(1):C207-16.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  139. Protective effects of butanol fraction from Betula Platyphyla var. japonica on cartilage alterations in a rabbit collagenase-induced osteoarthritis.
    Authors: Huh JE, Baek YH, Kim YJ, Lee JD, Choi DY, Park DS
    J Ethnopharmacol, 2009;123(3):515-21.
    Species: Rabbit
    Sample Type: Serum
  140. Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages.
    Authors: Cheon MS, Yoon T, Lee do Y, Choi G, Moon BC, Lee AY, Choo BK, Kim HK
    J Ethnopharmacol, 2009;122(3):473-7.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  141. Genistein enhances the effect of epidermal growth factor receptor tyrosine kinase inhibitors and inhibits nuclear factor kappa B in nonsmall cell lung cancer cell lines.
    Authors: Gadgeel SM, Ali S, Philip PA, Wozniak A, Sarkar FH
    Cancer, 2009;115(10):2165-76.
    Species: Human
    Sample Type: Cell Culture Supernates
  142. Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids.
    Authors: Mayer K, Kiessling A, Ott J, Schaefer MB, Hecker M, Henneke I, Schulz R, Gunther A, Wang J, Wu L, Roth J, Seeger W, Kang JX
    Am. J. Respir. Crit. Care Med., 2009;179(6):474-83.
    Species: Mouse
    Sample Type: BALF
  143. Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome.
    Authors: Campeau PM, Rafei M, Boivin MN, Sun Y, Grabowski GA, Galipeau J
    Blood, 2009;114(15):3181-90.
    Species: Human
    Sample Type: Cell Culture Supernates
  144. Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses.
    Authors: Zhou W, Newcomb DC, Moore ML, Goleniewska K, O'Neal JF, Peebles RS
    J. Immunol., 2008;181(8):5360-7.
    Species: Mouse
    Sample Type: Tissue Homogenates
  145. Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages.
    Authors: Pae HO, Jeong SO, Koo BS, Ha HY, Lee KM, Chung HT
    Biochem. Biophys. Res. Commun., 2008;371(3):361-5.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  146. Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.
    Authors: Castellano G, Malaponte G, Mazzarino MC, Figini M, Marchese F, Gangemi P, Travali S, Stivala F, Canevari S, Libra M
    Clin. Cancer Res., 2008;14(22):7470-80.
    Species: Human
    Sample Type: Plasma
  147. Effect of intensive atorvastatin therapy on prostaglandin E2 levels and metalloproteinase-9 activity in the plasma of patients with non-ST-elevation acute coronary syndrome.
    Authors: Gomez-Hernandez A, Sanchez-Galan E, Ortego M, Martin-Ventura JL, Blanco-Colio LM, Tarin-Vicente N, Jimenez-Nacher JJ, Lopez-Bescos L, Egido J, Tuñón J
    Am. J. Cardiol., 2008;102(1):12-8.
    Species: Human
    Sample Type: Plasma
  148. Porphyromonas gingivalis regulates the RANKL-OPG system in bone marrow stromal cells.
    Authors: Reddi D, Bostanci N, Hashim A, Aduse-Opoku J, Curtis MA, Hughes FJ, Belibasakis GN
    Microbes Infect., 2008;10(14):1459-68.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  149. Pulmonary stromal cells induce the generation of regulatory DC attenuating T-cell-mediated lung inflammation.
    Authors: Li Q, Guo Z, Xu X, Xia S, Cao X
    Eur. J. Immunol., 2008;38(10):2751-61.
    Species: Mouse
    Sample Type: BALF
  150. Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction.
    Authors: Niki Y, Takaishi H, Takito J, Miyamoto T, Kosaki N, Matsumoto H, Toyama Y, Tada N
    J. Immunol., 2007;179(1):639-46.
    Species: Mouse
    Sample Type: Serum
  151. 5-aminosalicylic acid improves indomethacin-induced enteropathy by inhibiting iNOS transcription in rats.
    Authors: Nandi J, Saud B, Zinkievich JM, Palma DT, Levine RA
    Dig. Dis. Sci., 2007;53(1):123-32.
    Species: Rat
    Sample Type: Tissue Homogenates
  152. Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice.
    Authors: Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA
    J. Immunol., 2007;179(3):1855-63.
    Species: Mouse
    Sample Type: BALF
  153. Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling.
    Authors: Liotta F, Angeli R, Cosmi L, Fili L, Manuelli C, Frosali F, Mazzinghi B, Maggi L, Pasini A, Lisi V, Santarlasci V, Consoloni L, Angelotti ML, Romagnani P, Parronchi P, Krampera M, Maggi E, Romagnani S, Annunziato F
    Stem Cells, 2007;26(1):279-89.
    Species: Human
    Sample Type: Cell Culture Supernates
  154. CCR1 and CCR5 chemokine receptors are involved in fever induced by LPS (E. coli) and RANTES in rats.
    Authors: Machado RR, Soares DM, Soares DM, Proudfoot AE, Proudfoot AE, Souza GE, Souza GE
    Brain Res., 2007;1161(0):21-31.
    Species: Rat
    Sample Type: CSF
  155. Requirement for protein kinase R in interleukin-1alpha-stimulated effects in cartilage.
    Authors: Tam CL, Hofbauer M, Towle CA
    Biochem. Pharmacol., 2007;74(11):1636-41.
    Species: Bovine
    Sample Type: Cell Culture Supernates
  156. Regional differences in prostaglandin E2 and nitric oxide production in the knee meniscus in response to dynamic compression.
    Authors: Hennerbichler A, Fermor B, Hennerbichler D, Weinberg JB, Guilak F
    Biochem. Biophys. Res. Commun., 2007;358(4):1047-53.
    Species: Porcine
    Sample Type: Cell Culture Supernates
  157. Endothelial Cell Response to Fusobacterium nucleatum.
    Authors: Mendes R, Pamuk F
    Infect Immun, 0;84(7):2141-8.
    Species: Human
    Sample Type: Cell Culture Supernates
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Average Rating: 4.7 (Based on 3 reviews)

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  Excellent
  Anonymous 11/03/2017
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Sample Tested Cell Culture Media

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Other Experimental Details Very easy to use, reliable results
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  Anonymous 05/02/2017
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Sample Tested Adipose tissue
 Prostaglandin E2 Parameter Assay Kit KGE004B Array KGE004B
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  Anonymous 06/21/2016
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 Prostaglandin E2 Parameter Assay Kit KGE004B
: Prostaglandin E2 Parameter Assay Kit [KGE004B].

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Sample Tested Mesenchymal stem cells

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