Prostaglandin I2 Synthase Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-68701

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Prostaglandin I2 Synthase Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GYALDFGKDAASFLTRMKEKHGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDEKARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAGSGWHEMGLLDFSYSFLLR

Reactivity Notes

Mouse 82%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Prostaglandin I2 Synthase Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Prostaglandin I2 Synthase Antibody [NBP2-68701]

Immunocytochemistry/ Immunofluorescence: Prostaglandin I2 Synthase Antibody [NBP2-68701]

Immunocytochemistry/Immunofluorescence: Prostaglandin I2 Synthase Antibody [NBP2-68701] - Staining of human cell line U-2 OS shows localization to endoplasmic reticulum.

Applications for Prostaglandin I2 Synthase Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation/Permeabilization: PFA/Triton X-100

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Prostaglandin I2 Synthase

PTGIS encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

Alternate Names

CYP8, CYP8A1, PGIS, Prostacyclin Synthase, PTGI

Gene Symbol

PTGIS

Additional Prostaglandin I2 Synthase Products

Product Documents for Prostaglandin I2 Synthase Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Prostaglandin I2 Synthase Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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