PTGFR Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-89045

Novus Biologicals
Discontinued Product
NBP2-89045 has been discontinued. View all PTGFR products.

Key Product Details

Species Reactivity

Mouse, Rat

Applications

Immunohistochemistry, Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Format

BSA Free
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Product Specifications

Immunogen

Synthetic peptide corresponding to the sequence near the N-terminus of rat PTGFR.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for PTGFR Antibody - BSA Free

PTGFR Antibody - BSA Free

Western Blot: PTGFR Antibody - BSA Free [NBP2-89045] -

Compromised PGF2 alpha signaling in PVN OXT neurons of repeated NTG-induced chronic migraine mice. A Quantification of PGF2 alpha level in PVN after NTG or vehicle injections. B and C RNAScope and immunofluorescent co-staining showing the expression of PTGFR mRNA in PVN OXT neurons, scale bar = 50 μm. D and E Western blot showing the expression of FP in PVN after NTG or vehicle injections. The data are presented as the mean +/- SEM. **P < 0.01, vs. Single NS group; ##P < 0.01, vs. Repeated NS group; &&P < 0.01, vs. Single NTG group. Bonferroni post-hoc test after One way ANOVA, n = 8 (A: F3,28=52.905, P < 0.001, eta-sq = 0.850, 95%CI 0.700-0.893; B: F3,28=25.591, P < 0.001, eta-sq = 0.733, 95%CI 0.491–0.809; E: F3,28=19.744, P < 0.001, eta-sq = 0.679, 95%CI 0.405–0.770) Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/40770605), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Applications for PTGFR Antibody - BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS containing 50% glycerol

Format

BSA Free

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTGFR

The prostaglandin F2-alpha receptor is a member of the Prostanoid Receptor subfamily. Along with various other prostaglandin receptors, it mediates the effects of prostaglandin F(2-alpha) which include modulation of intraocular pressure, corpus luteum regression, and possibly uterine smooth muscle contraction. Alternative mRNA splicing gives rise to two isoforms, FP(A) and FP(B), that differ in their intracellular carboxyl termini and result in different mechanisms for receptor internalization. Prostaglandin F2-alpha receptor expression has been documented in eye, ovary, placenta, and uterus. ESTs have been isolated from placental libraries.

Long Name

Prostaglandin F Receptor

Alternate Names

FP, PGF2-alpha Receptor

Gene Symbol

PTGFR

Additional PTGFR Products

Product Documents for PTGFR Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for PTGFR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for PTGFR Antibody - BSA Free

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Protocols

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FAQs

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