PU 02
1 Image
Description: Negative allosteric modulator of 5-HT3 receptors
Chemical Name: 6-[(1-Naphthalenylmethyl)thio]-9H-purine
Purity: ≥97%
Biological Activity
PU 02 is a negative allosteric modulator of 5-HT3 receptors (IC50 values are 0.36 and 0.73 μM in HEK293 cells transfected with human 5-HT3A and 5-HT3AB receptors respectively).Technical Data
M.Wt:
292.36
Formula:
C16H12N4S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at +4°C
CAS No:
313984-77-9
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Discovery of a novel allosteric modulator of 5-HT3 receptors: inhibition and potentiation of Cys-loop receptor signaling through a conserved transmembrane intersubunit site.
Trattnig et al.
J.Biol.Chem., 2012;287:25241
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsVersaClone cDNA Plasmids
Reviews for PU 02
There are currently no reviews for this product. Be the first to review PU 02 and earn rewards!
Have you used PU 02?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris Bioscience is the leading supplier of novel and exclusive
tools for
life science research with over 30 years' experience in the
industry.
Tocris is a Bio-Techne brand.
