Rat LILRC2 Biotinylated Antibody
Rat LILRC2 Biotinylated Antibody Summary
Accession # AAY44812
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Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
LILRC2 (leukocyte immunoglobulin-like receptor C2) is a 35 kDa member of a family of inhibitory and stimulatory receptors (LILRs) that are expressed on hematopoietic cells. Mature rat LILRC2 is a type I transmembrane (TM) protein that is 241 amino acids (aa) in length. It contains a 207 aa extracellular domain (ECD), a 19 aa TM segment, and a short cytoplasmic tail. The ECD contains two Ig-like domains while the TM segment possesses an Arg residue. This suggests that LILRC2 is an activating receptor that may interact with Fc epsilon RI gamma and/or CD3 zeta. Cells expressing LILRC2 include neutrophils, B cells, and CD4+ and CD8+ T cells. No human or mouse LILRC2 is known.
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