LILRC2 (leukocyte immunoglobulin-like receptor C2) is a 35 kDa member of a family of inhibitory and stimulatory receptors (LILRs) that are expressed on hematopoietic cells. Mature rat LILRC2 is a type I transmembrane (TM) protein that is 241 amino acids (aa) in length. It contains a 207 aa extracellular domain (ECD), a 19 aa TM segment, and a short cytoplasmic tail. The ECD contains two Ig-like domains while the TM segment possesses an Arg residue. This suggests that LILRC2 is an activating receptor that may interact with Fc epsilon RI gamma and/or CD3 zeta. Cells expressing LILRC2 include neutrophils, B cells, and CD4+ and CD8+ T cells. No human or mouse LILRC2 is known.
Key Product Details
Species Reactivity
Rat
Applications
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Sheep IgG
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant rat LILRC2
Gly24-Asn230
Accession # AAY44812
Gly24-Asn230
Accession # AAY44812
Specificity
Detects rat LILRC2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant rat LILRC1 is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Rat LILRC2 Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Rat LILRC2
Sample: Recombinant Rat LILRC2
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
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Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: LILRC2
Long Name
Leukocyte Immunoglobulin-like Receptor C2
Entrez Gene IDs
690906 (Rat)
Gene Symbol
LILRC2
UniProt
Additional LILRC2 Products
Product Documents for Rat LILRC2 Antibody
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Rat LILRC2 Antibody
For research use only
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Protocols
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