Recombinant Human BMP-4 Protein

Formulations:
Catalog # Availability Size / Price Qty
314-BP-010
314-BP-050
314-BP-01M
314-BP-500
Recombinant Human BMP-4 Protein Bioactivity
2 Images
Product Details
Citations (352)
FAQs
Reviews

Recombinant Human BMP-4 Protein Summary

Purity
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.01 EU per 1 μg of the protein by the LAL method.
Activity
Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Binnerts, M.E. et al. (2004) Biochem. Biophys. Res. Commun. 315(2):272. The ED50 for this effect is typically 2.5-15 ng/mL.
Source
Mouse myeloma cell line, NS0-derived human BMP-4 protein
Ser293-Arg408
Accession #
N-terminal Sequence
Analysis
Ser293
Structure / Form
Disulfide-linked homodimer
Predicted Molecular Mass
13 kDa (monomer)
SDS-PAGE
22-25 kDa, reducing conditions
37-41 kDa, non-reducing conditions

Product Datasheets

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

314-BP

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Reconstitution Reconstitute at 50-200 μg/mL in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -70 °C under sterile conditions after reconstitution.

314-BP/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Reconstitution Reconstitute at 50-200 μg/mL in sterile 4 mM HCl.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity View Larger

Recombinant Human BMP-4 (Catalog # 314-BP/CF) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED50for this effect is 2.5-15 ng/mL.

SDS-PAGE View Larger

1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: BMP-4

BMP-4 is a TGF-beta superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair (1-5). The human BMP-4 precursor contains a 273 amino acid (aa) propeptide and a 116 aa mature protein (6). Processing of the propeptide by furin or proprotein convertase 6 enables the formation of the mature disulfide-linked homodimeric BMP-4 and facilitates its secretion. Similar intracellular processes may lead to the formation and recreation of BMP4/BMP7
disulfide-linked heterodimer (7-9). Mature human and mouse BMP-4 share 98% aa sequence identity. Human BMP-4 shares 85% aa sequence identity with human BMP-2 and less than 50% with other human BMPs. Compared to BMP-4 homodimers, BMP-4/BMP-7 heterodimers exhibit a greater potency in inducing osteogenic differentiation (9). In Xenopus, the heterodimers can also induce the formation of mesoderm, whereas BMP-4 homodimers only provide ventralizing signals for existing mesoderm (10). BMP-4 signals through tetrameric complexes composed of type I (primarily Activin RIA or BMPR-IA) and type II (primarily Activin RIIA or BMPR-II) receptors (11, 12). The bioavailability of BMP-4 is regulated by its interaction with multiple proteins and glycosaminoglycans (13-15).

 

References
  1. Zhang, P. et al. (2008) Blood 111:1933.
  2. Gambaro, K. et al. (2006) Cell Death Differ. 13:1075.
  3. Simic, P. and S. Vukicevic (2005) Cytokine Growth Factor Rev. 16:299.
  4. Sadlon, T.J. et al. (2004) Stem Cells 22:457.
  5. Frank, D.B. et al. (2005) Circ. Res. 97:496.
  6. Wozney, J. et al. (1988) Science 242:1528.
  7. Cui, Y. et al. (1998) EMBO J. 17:4735.
  8. Cui, Y. et al. (2001) Genes Dev. 15:2797.
  9. Aono, A. et al. (1995) Biochem. Biophys. Res. Commun. 210:670.
  10. Nishimatsu, S. and G.H. Thomsen (1998) Mech. Dev. 74:75.
  11. Chen, D. et al. (2004) Growth Factors 22:233.
  12. Lavery, K. et al. (2008) J. Biol. Chem. April 24 epub.
  13. Rosen, V. (2006) Ann. N.Y. Acad. Sci. 1068:19.
  14. Jones, C.M. and J.C. Smith (1998) Dev. Biol. 194:12.
  15. Takada, T. et al. (2003) J. Biol. Chem. 278:43229.
Long Name
Bone Morphogenetic Protein 4
Entrez Gene IDs
652 (Human); 12159 (Mouse); 25296 (Rat); 30612 (Zebrafish)
Alternate Names
BMP2B; BMP-2B; BMP2B1; BMP2BMCOPS6; BMP4; BMP-4; Bone morphogenetic protein 2B; bone morphogenetic protein 4; DVR4; MCOPS6; OFC11; ZYME

Citations for Recombinant Human BMP-4 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

352 Citations: Showing 1 - 10
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  1. TATA box-binding protein-related factor 3 drives the mesendoderm specification of human embryonic stem cells by globally interacting with the TATA box of key mesendodermal genes
    Authors: H Liang, P Zhang, HJ Bai, J Huang, HT Yang
    Stem Cell Res Ther, 2020;11(1):196.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  2. Noggin depletion in adipocytes promotes obesity in mice
    Authors: AM Blázquez-M, M Jumabay, P Rajbhandar, T Sallam, Y Guo, J Yao, L Vergnes, K Reue, L Zhang, Y Yao, AM Fogelman, P Tontonoz, AJ Lusis, X Wu, KI Boström
    Mol Metab, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Controlled modelling of human epiblast and amnion development using stem cells
    Authors: Y Zheng, X Xue, Y Shao, S Wang, SN Esfahani, Z Li, JM Muncie, JN Lakins, VM Weaver, DL Gumucio, J Fu
    Nature, 2019;573(7774):421-425.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Manipulating energy migration within single lanthanide activator for switchable upconversion emissions towards bidirectional photoactivation
    Authors: Q Mei, A Bansal, MKG Jayakumar, Z Zhang, J Zhang, H Huang, D Yu, CJA Ramachandr, DJ Hausenloy, TW Soong, Y Zhang
    Nat Commun, 2019;10(1):4416.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. A versatile toolbox for knock-in gene targeting based on the Multisite Gateway technology
    Authors: S Yoshimatsu, T Sone, M Nakajima, T Sato, R Okochi, M Ishikawa, M Nakamura, E Sasaki, S Shiozawa, H Okano
    PLoS ONE, 2019;14(8):e0221164.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors
    Authors: JM Segal, D Kent, DJ Wesche, SS Ng, M Serra, B Oulès, G Kar, G Emerton, SJI Blackford, S Darmanis, R Miquel, TV Luong, R Yamamoto, A Bonham, W Jassem, N Heaton, A Vigilante, A King, R Sancho, S Teichmann, SR Quake, H Nakauchi, ST Rashid
    Nat Commun, 2019;10(1):3350.
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  7. CRISPR/Cas9 mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients
    Authors: M Nasri, M Ritter, P Mir, B Dannenmann, N Aghaallaei, D Amend, V Makaryan, Y Xu, B Fletcher, R Bernhard, I Steiert, K Hahnel, J Berger, I Koch, B Sailer, K Hipp, C Zeidler, M Klimiankou, B Bajoghli, DC Dale, K Welte, J Skokowa
    Haematologica, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells
    Authors: C Song, F Xu, Z Ren, Y Zhang, Y Meng, Y Yang, S Lingadahal, E Cheung, G Li, W Liu, J Wan, Y Zhao, G Chen
    Stem Cell Reports, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  9. SMYD2 Drives Mesendodermal Differentiation of Human Embryonic Stem Cells through Mediating the Transcriptional Activation of Key Mesendodermal Genes
    Authors: HJ Bai, P Zhang, L Ma, H Liang, G Wei, HT Yang
    Stem Cells, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model
    Authors: S Pecha, K Yorgan, M Röhl, B Geertz, A Hansen, F Weinberger, S Sehner, H Ehmke, H Reichenspu, T Eschenhage, AP Schwoerer
    Sci Rep, 2019;9(1):9831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  11. High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds
    Authors: STJ Bradford, EJ Ranghini, E Grimley, PH Lee, GR Dressler
    J. Biol. Chem., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Orexin A modulates prolactin production by regulating BMP-4 activity in rat pituitary lactotorope cells
    Authors: S Fujisawa, M Komatsubar, K Ogura-Ochi, N Tsukamoto-, K Toma, K Inagaki, J Wada, F Otsuka
    Peptides, 2019;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application
    Authors: E Ito, S Miyagawa, M Takeda, A Kawamura, A Harada, H Iseoka, S Yajima, N Sougawa, N Mochizuki-, S Yasuda, Y Sato, Y Sawa
    Sci Rep, 2019;9(1):1881.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Autonomous trisomic rescue of Down syndrome cells
    Authors: M Inoue, K Kajiwara, A Yamaguchi, T Kiyono, O Samura, H Akutsu, H Sago, A Okamoto, A Umezawa
    Lab. Invest., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
    Authors: B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat
    Cell Rep, 2019;27(2):599-615.e12.
    Species: Human
    Sample Types: cell culture
    Applications: Differentiation
  16. Cell population balance of cardiovascular spheroids derived from human induced pluripotent stem cells
    Authors: Y Yan, J Bejoy, J Xia, K Griffin, J Guan, Y Li
    Sci Rep, 2019;9(1):1295.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma
    Authors: R Sachdeva, M Wu, K Johnson, H Kim, A Celebre, U Shahzad, MS Graham, JA Kessler, JH Chuang, J Karamchand, M Bredel, R Verhaak, S Das
    Sci Rep, 2019;9(1):14569.
    Species: Human
    Sample Types: Whole Cells
    Applications: Tissue Culture
  18. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
    Authors: RMJ Genga, EM Kernfeld, KM Parsi, TJ Parsons, MJ Ziller, R Maehr
    Cell Rep, 2019;27(3):708-718.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  19. Generation of human antral and fundic gastric organoids from pluripotent stem cells
    Authors: TR Broda, KW McCracken, JM Wells
    Nat Protoc, 2019;14(1):28-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Serum of patients with acute myocardial infarction prevents inflammation in iPSC-cardiomyocytes
    Authors: K Sattler, I El-Battraw, Z Zhao, C Schrottenb, G Yücel, H Lan, X Li, S Lang, WH Zimmermann, L Cyganek, J Utikal, T Wieland, U Ravens, K Bieback, M Borggrefe, X Zhou, I Akin
    Sci Rep, 2019;9(1):5651.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Feather arrays are patterned by interacting signalling and cell density waves
    Authors: WKW Ho, L Freem, D Zhao, KJ Painter, TE Woolley, EA Gaffney, MJ McGrew, A Tzika, MC Milinkovit, P Schneider, A Drusko, F Matthäus, JD Glover, KL Wells, JA Johansson, MG Davey, HM Sang, M Clinton, DJ Headon
    PLoS Biol., 2019;17(2):e3000132.
    Species: Chicken
    Sample Types: Tissue Explants
    Applications: Bioassay
  22. Derivation of enteric neuron lineages from human pluripotent stem cells
    Authors: K Barber, L Studer, F Fattahi
    Nat Protoc, 2019;14(4):1261-1279.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  23. FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration
    Authors: P Yan, Q Li, L Wang, P Lu, K Suzuki, Z Liu, J Lei, W Li, X He, S Wang, J Ding, P Chan, W Zhang, M Song, JC Izpisua Be, J Qu, F Tang, GH Liu
    Cell Stem Cell, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  24. TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment
    Authors: L Li, Y Wang, JL Torkelson, G Shankar, JM Pattison, HH Zhen, F Fang, Z Duren, J Xin, S Gaddam, SP Melo, SN Piekos, J Li, EJ Liaw, L Chen, R Li, M Wernig, WH Wong, HY Chang, AE Oro
    Cell Stem Cell, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Function and Immunogenicity of Gene-corrected iPSC-derived Hepatocyte-Like Cells in Restoring Low Density Lipoprotein Uptake in Homozygous Familial Hypercholesterolemia
    Authors: H Okada, C Nakanishi, S Yoshida, M Shimojima, J Yokawa, M Mori, H Tada, T Yoshimuta, K Hayashi, T Yamano, R Hanayama, M Yamagishi, MA Kawashiri
    Sci Rep, 2019;9(1):4695.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  26. FGF signal is not required for hepatoblast differentiation of human iPS cells
    Authors: Y Toba, A Kiso, S Nakamae, F Sakurai, K Takayama, H Mizuguchi
    Sci Rep, 2019;9(1):3713.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells
    Authors: A Montel-Hag, CS Seet, S Li, B Chick, Y Zhu, P Chang, S Tsai, V Sun, S Lopez, HC Chen, C He, CJ Chin, D Casero, GM Crooks
    Cell Stem Cell, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Synchrony and asynchrony between an epigenetic clock and developmental timing
    Authors: A Hoshino, S Horvath, A Sridhar, A Chitsazan, TA Reh
    Sci Rep, 2019;9(1):3770.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
    Authors: H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta
    Cell Stem Cell, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse
    Authors: AD Senft, EK Bikoff, EJ Robertson, I Costello
    Nat Commun, 2019;10(1):1089.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair
    Authors: T Colunga, M Hayworth, S Kre beta, DM Reynolds, L Chen, KL Nazor, J Baur, AM Singh, JF Loring, M Metzger, S Dalton
    Cell Rep, 2019;26(10):2566-2579.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes
    Authors: MJ Harms, Q Li, S Lee, C Zhang, B Kull, S Hallen, A Thorell, I Alexanders, CE Hagberg, XR Peng, A Mardinoglu, KL Spalding, J Boucher
    Cell Rep, 2019;27(1):213-225.e5.
    Species: Human
    Sample Types: Tissue Explants
    Applications: Bioassay
  33. NKL homeobox gene activities in normal and malignant myeloid cells
    Authors: S Nagel, M Scherr, RAF MacLeod, C Pommerenke, M Koeppel, C Meyer, M Kaufmann, I Dallmann, HG Drexler
    PLoS ONE, 2019;14(12):e0226212.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
    Authors: A Stubb, C Guzmán, E Närvä, J Aaron, TL Chew, M Saari, M Miihkinen, G Jacquemet, J Ivaska
    Nat Commun, 2019;10(1):4756.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies
    Authors: M Ali, F Kabir, JJ Thomson, Y Ma, C Qiu, M Delannoy, SY Khan, SA Riazuddin
    Sci Rep, 2019;9(1):18552.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Modeling the Effects of Severe Metabolic Disease by Genome Editing of hPSC-Derived Endothelial Cells Reveals an Inflammatory Phenotype
    Authors: F Roudnicky, Y Lan, M Friesen, G Dernick, JD Zhang, A Staempfli, N Bordag, A Wagner-Gol, K Christense, M Ebeling, M Graf, M Burcin, CA Meyer, CA Cowan, C Patsch
    Int J Mol Sci, 2019;20(24):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Chemically-Defined, Xeno-Free, Scalable Production of hPSC-Derived Definitive Endoderm Aggregates with Multi-Lineage Differentiation Potential
    Authors: A Sahabian, M Sgodda, O Naujok, R Dettmer, J Dahlmann, F Manstein, T Cantz, R Zweigerdt, U Martin, R Olmer
    Cells, 2019;8(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Adequate taylor couette flow-mediated shear stress is useful for dissociating human iPS cell-derived cell aggregates
    Authors: K Matsuura, M Wada, K Sakaguchi, Y Matsuhashi, T Shimizu
    Regen Ther, 2019;12(0):6-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors
    Authors: D Chen, N Sun, L Hou, R Kim, J Faith, M Aslanyan, Y Tao, Y Zheng, J Fu, W Liu, M Kellis, A Clark
    Cell Rep, 2019;29(13):4568-4582.e5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  40. Supplementation of vitamin C promotes early germ cell specification from human embryonic stem cells
    Authors: Z Li, F Fang, Q Zhao, H Li, C Xiong
    Stem Cell Res Ther, 2019;10(1):324.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  41. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
    Authors: J Grajcarek, J Monlong, Y Nishinaka-, M Nakamura, M Nagai, S Matsuo, D Lougheed, H Sakurai, MK Saito, G Bourque, K Woltjen
    Nat Commun, 2019;10(1):4856.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant
    Authors: V Veschi, LR Mangiapane, A Nicotra, S Di Franco, E Scavo, T Apuzzo, DS Sardina, M Fiori, A Benfante, ML Colorito, G Cocorullo, F Giuliante, C Cipolla, G Pistone, MR Bongiorno, A Rizzo, CM Tate, X Wu, S Rowlinson, LF Stancato, M Todaro, R De Maria, G Stassi
    Oncogene, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Engineering transferrable microvascular meshes for subcutaneous islet transplantation
    Authors: W Song, A Chiu, LH Wang, RE Schwartz, B Li, N Bouklas, DT Bowers, D An, SH Cheong, JA Flanders, Y Pardo, Q Liu, X Wang, VK Lee, G Dai, M Ma
    Nat Commun, 2019;10(1):4602.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  44. Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells
    Authors: W Liang, P Han, EH Kim, J Mak, R Zhang, AG Torrente, JI Goldhaber, E Marbán, HC Cho
    Stem Cells, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation
    Authors: GL Tiemeier, G Wang, SJ Dumas, WMPJ Sol, MC Avramut, T Karakach, VV Orlova, CW van den Be, CL Mummery, P Carmeliet, BM van den Be, TJ Rabelink
    Stem Cell Reports, 2019;13(5):803-816.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  46. The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway
    Authors: D Seo, SM Jung, JS Park, J Lee, J Ha, M Kim, SH Park
    EBioMedicine, 2019;49(0):55-71.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  47. Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells
    Authors: A Jacob, M Vedaie, DA Roberts, DC Thomas, C Villacorta, KD Alysandrat, F Hawkins, DN Kotton
    Nat Protoc, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Preconditioning the Initial State of Feeder-free Human Pluripotent Stem Cells Promotes Self-formation of Three-dimensional Retinal Tissue
    Authors: A Kuwahara, S Yamasaki, M Mandai, K Watari, K Matsushita, M Fujiwara, Y Hori, Y Hiramine, D Nukaya, M Iwata, A Kishino, M Takahashi, Y Sasai, T Kimura
    Sci Rep, 2019;9(1):18936.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype
    Authors: F Wang, V Zachar, CP Pennisi, T Fink, Y Maeda, J Emmersen
    Int J Mol Sci, 2018;19(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. ATOH1/RFX1/RFX3 transcription factors facilitate the differentiation and characterisation of inner ear hair cell-like cells from patient-specific induced pluripotent stem cells harbouring A8344G mutation of mitochondrial DNA
    Authors: YC Chen, CL Tsai, YH Wei, YT Wu, WT Hsu, HC Lin, YC Hsu
    Cell Death Dis, 2018;9(4):437.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
    Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
    Sci Rep, 2018;8(1):1561.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Human iPS Cell-based Liver-like Tissue Engineering at Extrahepatic Sites in Mice as a New Cell Therapy for Hemophilia B
    Authors: R Okamoto, K Takayama, N Akita, Y Nagamoto, D Hosokawa, S Iizuka, F Sakurai, H Suemizu, K Ohashi, H Mizuguchi
    Cell Transplant, 2018;27(2):299-309.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation
    Authors: JJ Gell, J Zhao, D Chen, TJ Hunt, AT Clark
    Stem Cell Res, 2018;27(0):46-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis
    Authors: X Guo, Y Xu, Z Wang, Y Wu, J Chen, G Wang, C Lu, W Jia, J Xi, S Zhu, Z Jiapaer, X Wan, Z Liu, S Gao, J Kang
    Cell Stem Cell, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development
    Authors: K Koefoed, J Skat-Rørda, P Andersen, CB Warzecha, M Pye, TA Andersen, KD Ajbro, E Bendsen, M Narimatsu, F Vilhardt, LB Pedersen, JL Wrana, RH Anderson, K Møllgård, ST Christense, LA Larsen
    Sci Rep, 2018;8(1):9542.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Barrier properties and transcriptome expression in human iPSC-derived models of the blood-brain barrier
    Authors: L Delsing, P Dönnes, J Sánchez, M Clausen, D Voulgaris, A Falk, A Herland, G Brolén, H Zetterberg, R Hicks, J Synnergren
    Stem Cells, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage
    Authors: V Pursani, D Bhartiya, V Tanavde, M Bashir, P Sampath
    Stem Cell Res Ther, 2018;9(1):97.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Functional 3D Human Liver Bud Assembled from MSC-Derived Multiple Liver Cell Lineages
    Authors: J Li, F Xing, F Chen, L He, KF So, Y Liu, J Xiao
    Cell Transplant, 2018;0(0):9636897187803.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
    Authors: Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang, D Al Alam, S Danopoulos, M Mori, YW Chen, R Balasubram, SM Chuva de S, C Serra, M Bialecka, E Kim, S Lin, ALR Toste de C, PN Riccio, WV Cardoso, X Zhang, HW Snoeck, J Que
    Cell Stem Cell, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Effects of lung and airway epithelial maturation cocktail on the structure of lung bud organoids
    Authors: E Magro-Lope, C Palmer, J Manso, I Liste, A Zambrano
    Stem Cell Res Ther, 2018;9(1):186.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Induced pluripotent stem cell line from an atopic dermatitis patient heterozygous for c.2282del4 mutation in filaggrin: KCLi001-A
    Authors: L Devito, M Donne, N Kolundzic, P Khurana, C Hobbs, G Kaddour, S Dubrac, R Gruber, M Schmuth, T Mauro, D Ilic
    Stem Cell Res, 2018;31(0):122-126.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Intrinsic cellular chirality regulates left-right symmetry breaking during cardiac looping
    Authors: P Ray, AS Chin, KE Worley, J Fan, G Kaur, M Wu, LQ Wan
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Species: Chicken
    Sample Types: Embryo
    Applications: Bioassay
  63. Improving Cell Survival in Injected Embryos Allows Primed Pluripotent Stem Cells to Generate Chimeric Cynomolgus Monkeys
    Authors: Y Kang, Z Ai, K Duan, C Si, Y Wang, Y Zheng, J He, Y Yin, S Zhao, B Niu, X Zhu, L Liu, L Xiang, L Zhang, Y Niu, W Ji, T Li
    Cell Rep, 2018;25(9):2563-2576.e9.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits
    Authors: JGW Smith, T Owen, JR Bhagwan, D Mosqueira, E Scott, I Mannhardt, A Patel, R Barriales-, L Monserrat, A Hansen, T Eschenhage, SE Harding, S Marston, C Denning
    Stem Cell Reports, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition
    Authors: K Kirino, T Nakahata, T Taguchi, MK Saito
    Sci Rep, 2018;8(1):12865.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Analysis of differentially expressed genes among human hair follicle-derived iPSCs, induced hepatocyte-like cells, and primary hepatocytes
    Authors: Z Xu, X He, X Shi, Y Xia, X Liu, H Wu, P Li, H Zhang, W Yin, X Du, L Li, Y Li
    Stem Cell Res Ther, 2018;9(1):211.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis
    Authors: CC Weng, PY Ding, YH Liu, JR Hawse, M Subramania, CC Wu, YC Lin, CY Chen, WC Hung, KH Cheng
    Oncogene, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Cardiomyocytes Derived from Human CardiopoieticAmniotic Fluids
    Authors: A Di Baldass, MA D'Amico, P Izzicupo, G Gaggi, S Guarnieri, MA Mariggiò, I Antonucci, B Corneo, D Sirabella, L Stuppia, B Ghinassi
    Sci Rep, 2018;8(1):12028.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  69. Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming
    Authors: AD Senft, I Costello, HW King, AW Mould, EK Bikoff, EJ Robertson
    Cell Rep, 2018;24(8):1977-1985.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs
    Authors: S Frank, G Ahuja, D Bartsch, N Russ, W Yao, JC Kuo, JP Derks, VS Akhade, Y Kargapolov, T Georgomano, JE Messling, M Gramm, L Brant, R Rehimi, NE Vargas, A Kuroczik, TP Yang, RGA Sahito, J Franzen, J Hescheler, A Sachinidis, M Peifer, A Rada-Igles, M Kanduri, IG Costa, C Kanduri, A Papantonis, L Kurian
    Cell Stem Cell, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  71. The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation
    Authors: D Chen, W Liu, J Zimmerman, WA Pastor, R Kim, L Hosohama, J Ho, M Aslanyan, JJ Gell, SE Jacobsen, AT Clark
    Cell Rep, 2018;25(13):3591-3602.e5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing
    Authors: SS Adkar, CL Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, CA Gersbach, F Guilak
    Stem Cells, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment
    Authors: JM Pattison, SP Melo, SN Piekos, JL Torkelson, E Bashkirova, MR Mumbach, C Rajasingh, HH Zhen, L Li, E Liaw, D Alber, AJ Rubin, G Shankar, X Bao, HY Chang, PA Khavari, AE Oro
    Nat. Genet., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling
    Authors: H Jun, H Yu, J Gong, J Jiang, X Qiao, E Perkey, DI Kim, MP Emont, AG Zestos, JS Cho, J Liu, RT Kennedy, I Maillard, XZS Xu, J Wu
    Nat. Med., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
    Authors: A Yoney, F Etoc, A Ruzo, T Carroll, JJ Metzger, I Martyn, S Li, C Kirst, ED Siggia, AH Brivanlou
    Elife, 2018;7(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery
    Authors: Y Jin, Y Liu, Z Li, K Santostefa, J Shi, X Zhang, D Wu, Z Cheng, W Wu, N Terada, S Jin, F Bai
    PLoS ONE, 2018;13(3):e0194895.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions
    Authors: A Yachie-Kin, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, PW Zandstra
    Mol. Syst. Biol., 2018;14(1):e7952.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Beta-Catenin maintains lung epithelial progenitors after lung specification
    Authors: EJ Ostrin, DR Little, KN Gerner-Mau, EA Sumner, R Ríos-Corzo, E Ambrosio, SE Holt, NR Forcioli-C, H Akiyama, SM Hanash, S Kimura, SXL Huang, J Chen
    Development, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Billion-scale production of hepatocyte-like cells from human induced pluripotent stem cells
    Authors: T Yamashita, K Takayama, F Sakurai, H Mizuguchi
    Biochem. Biophys. Res. Commun., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Differentiation
  80. Extracellular bone morphogenetic protein modulator BMPER and twisted gastrulation homolog 1 preserve arterial-venous specification in zebrafish blood vessel development and regulate Notch signaling in endothelial cells
    Authors: JS Esser, RE Steiner, M Deckler, H Schmitt, B Engert, S Link, A Charlet, C Patterson, C Bode, Q Zhou, M Moser
    FEBS J., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing
    Authors: C Long, H Li, M Tiburcy, C Rodriguez-, V Kyrychenko, H Zhou, Y Zhang, YL Min, JM Shelton, PPA Mammen, NY Liaw, WH Zimmermann, R Bassel-Dub, JW Schneider, EN Olson
    Sci Adv, 2018;4(1):eaap9004.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  82. TCF7L1 suppresses primitive streak gene expression to support human embryonic stem cell pluripotency
    Authors: RA Sierra, NP Hoverter, RN Ramirez, LM Vuong, A Mortazavi, BJ Merrill, ML Waterman, PJ Donovan
    Development, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Simplified footprint-free Cas9/CRISPR editing of cardiac-associated genes in human pluripotent stem cells
    Authors: A Kondrashov, M Duc Hoang, J Smith, J Bhagwan, G Duncan, D Mosqueira, M Munoz, NTN Vo, C Denning
    Stem Cells Dev., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
    Authors: A Buskin, L Zhu, V Chichagova, B Basu, S Mozaffari-, D Dolan, A Droop, J Collin, R Bronstein, S Mehrotra, M Farkas, G Hilgen, K White, KT Pan, A Treumann, D Hallam, K Bialas, G Chung, C Mellough, Y Ding, N Krasnogor, S Przyborski, S Zwolinski, J Al-Aama, S Alharthi, Y Xu, G Wheway, K Szymanska, M McKibbin, CF Inglehearn, DJ Elliott, S Lindsay, RR Ali, DH Steel, L Armstrong, E Sernagor, H Urlaub, E Pierce, R Lührmann, SN Grellschei, CA Johnson, M Lako
    Nat Commun, 2018;9(1):4234.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Rapid DNA replication origin licensing protects stem cell pluripotency
    Authors: JP Matson, R Dumitru, P Coryell, RM Baxley, W Chen, K Twaroski, BR Webber, J Tolar, AK Bielinsky, JE Purvis, JG Cook
    Elife, 2017;6(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Human ESC/iPSC-Derived Hepatocyte-like Cells Achieve Zone-Specific Hepatic Properties by Modulation of WNT Signaling
    Authors: S Mitani, K Takayama, Y Nagamoto, K Imagawa, F Sakurai, M Tachibana, R Sumazaki, H Mizuguchi
    Mol. Ther., 2017;25(6):1420-1433.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Highly Efficient Differentiation of Endothelial Cells from Pluripotent Stem Cells Requires the MAPK and the PI3K Pathways
    Authors: A Harding, E Cortez-Tol, NL Magner, JR Beegle, DP Coleal-Ber, D Hao, A Wang, JA Nolta, P Zhou
    Stem Cells, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection
    Authors: F Sakurai, S Mitani, T Yamamoto, K Takayama, M Tachibana, K Watashi, T Wakita, S Iijima, Y Tanaka, H Mizuguchi
    Sci Rep, 2017;7(0):45698.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract
    Authors: BA Boswell, A Korol, JA West-Mays, LS Musil
    Mol. Biol. Cell, 2017;0(0):.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Supraphysiological levels of GDF11 induce striated muscle atrophy
    Authors: DW Hammers, M Merscham-B, JY Hsiao, S Engst, JJ Hartman, HL Sweeney
    EMBO Mol Med, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells
    Authors: E Giacomelli, M Bellin, L Sala, BJ van Meer, LG Tertoolen, VV Orlova, CL Mummery
    Development, 2017;144(6):1008-1017.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  92. In Vitro Micropatterned Human Pluripotent Stem Cell Test (�P-hPST) for Morphometric-Based Teratogen Screening
    Authors: J Xing, Y Cao, Y Yu, H Li, Z Song, H Yu
    Sci Rep, 2017;7(1):8491.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells
    Authors: F Hawkins, P Kramer, A Jacob, I Driver, DC Thomas, KB McCauley, N Skvir, AM Crane, AA Kurmann, AN Hollenberg, S Nguyen, BG Wong, AS Khalil, SX Huang, S Guttentag, JR Rock, JM Shannon, BR Davis, DN Kotton
    J. Clin. Invest., 2017;127(6):2277-2294.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair
    Authors: M Tiburcy, JE Hudson, P Balfanz, S Schlick, T Meyer, ML Chang Liao, E Levent, F Raad, S Zeidler, E Wingender, J Riegler, M Wang, JD Gold, I Kehat, E Wettwer, U Ravens, P Dierickx, LW van Laake, MJ Goumans, S Khadjeh, K Toischer, G Hasenfuss, LA Couture, A Unger, WA Linke, T Araki, B Neel, G Keller, L Gepstein, JC Wu, WH Zimmermann
    Circulation, 2017;135(19):1832-1847.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
    Authors: AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, A Solovyov, C Husser, M Olszewska, J Teruya-Fel, D Perumal, VM Klimek, A Spyridonid, RK Rampal, L Silverman, EP Reddy, E Papaemmanu, S Parekh, BD Greenbaum, CS Leslie, MG Kharas, EP Papapetrou
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells
    Authors: D Jung, J Xiong, M Ye, X Qin, L Li, S Cheng, M Luo, J Peng, J Dong, F Tang, W Shen, MM Matzuk, K Kee
    Nat Commun, 2017;8(0):15680.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells
    Authors: C Sallon, I Callebaut, I Boulay, J Fontaine, D Logeart-Av, C Henriquet, M Pugnière, X Cayla, P Monget, G Harichaux, V Labas, S Canepa, C Taragnat
    J. Biol. Chem., 2017;0(0):.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  98. Pericyte-derived Bone Morphogenetic Protein 4 Underlies White Matter Damage after Chronic Hypoperfusion
    Authors: MT Uemura, M Ihara, T Maki, T Nakagomi, S Kaji, K Uemura, T Matsuyama, RN Kalaria, A Kinoshita, R Takahashi
    Brain Pathol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Fetal Therapy Model of Myelomeningocele with Three-Dimensional Skin Using Amniotic Fluid Cell-Derived Induced Pluripotent Stem Cells
    Authors: K Kajiwara, T Tanemoto, S Wada, J Karibe, N Ihara, Y Ikemoto, T Kawasaki, Y Oishi, O Samura, K Okamura, S Takada, H Akutsu, H Sago, A Okamoto, A Umezawa
    Stem Cell Reports, 2017;8(6):1701-1713.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  100. Recapitulating and Correcting Marfan Syndrome in a Cellular Model
    Authors: JW Park, L Yan, C Stoddard, X Wang, Z Yue, L Crandall, T Robinson, Y Chang, K Denton, E Li, B Jiang, Z Zhang, K Martins-Ta, SP Yee, H Nie, F Gu, W Si, T Xie, L Yue, RH Xu
    Int. J. Biol. Sci., 2017;13(5):588-603.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence
    Authors: N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra
    Nat Commun, 2017;8(0):15380.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Bone morphogenetic protein-7 (BMP-7) augments insulin sensitivity in mice with type II diabetes mellitus by potentiating PI3K/AKT pathway
    Authors: T Chattopadh, RR Singh, S Gupta, A Surolia
    Biofactors, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Serum Proteases Potentiate BMP-Induced Cell Cycle Re-entry of Dedifferentiating Muscle Cells during Newt Limb Regeneration
    Authors: I Wagner, H Wang, PM Weissert, WL Straube, A Shevchenko, M Gentzel, G Brito, A Tazaki, C Oliveira, T Sugiura, A Shevchenko, A Simon, DN Drechsel, EM Tanaka
    Dev. Cell, 2017;40(6):608-617.e6.
    Applications: Western Blot
  104. Nutritional modulation of mouse and human liver bud growth through a branched-amino acid metabolism
    Authors: H Koike, RR Zhang, Y Ueno, K Sekine, YW Zheng, T Takebe, H Taniguchi
    Development, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Efficient production of trophoblast lineage cells from human induced pluripotent stem cells
    Authors: J Kojima, A Fukuda, H Taira, T Kawasaki, H Ito, N Kuji, K Isaka, A Umezawa, H Akutsu
    Lab. Invest, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium
    Authors: N Yucer, M Holzapfel, T Jenkins Vo, L Lenaeus, L Ornelas, A Laury, D Sareen, R Barrett, BY Karlan, CN Svendsen
    Sci Rep, 2017;7(1):10741.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium
    Authors: J Li, I Minami, M Shiozaki, L Yu, S Yajima, S Miyagawa, Y Shiba, N Morone, S Fukushima, M Yoshioka, S Li, J Qiao, X Li, L Wang, H Kotera, N Nakatsuji, Y Sawa, Y Chen, L Liu
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Wnt/?-catenin promotes gastric fundus specification in mice and humans
    Authors: KW McCracken, E Aihara, B Martin, CM Crawford, T Broda, J Treguier, X Zhang, JM Shannon, MH Montrose, JM Wells
    Nature, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Development of a human cardiac organoid injury model reveals innate regenerative potential
    Authors: HK Voges, RJ Mills, DA Elliott, RG Parton, ER Porrello, JE Hudson
    Development, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  110. In�Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling
    Authors: K Yamamizu, M Iwasaki, H Takakubo, T Sakamoto, T Ikuno, M Miyoshi, T Kondo, Y Nakao, M Nakagawa, H Inoue, JK Yamashita
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity
    Authors: Y Choudhury, YC Toh, J Xing, Y Qu, J Poh, L Huan, HS Tan, R Kanesvaran, H Yu, MH Tan
    Sci Rep, 2017;7(0):41238.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Expression of the Human Herpesvirus 6A Latency-Associated Transcript U94A Disrupts Human Oligodendrocyte Progenitor Migration
    Authors: A Campbell, JM Hogestyn, CJ Folts, B Lopez, C Pröschel, D Mock, M Mayer-Prös
    Sci Rep, 2017;7(1):3978.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency
    Authors: JH Lee, S Laronde, TJ Collins, Z Shapovalov, B Tanasijevi, JD McNicol, A Fiebig-Com, YD Benoit, JB Lee, RR Mitchell, M Bhatia
    Cell Rep, 2017;19(1):20-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  114. Human iPSC-derived myocardium-on-chip with capillary-like flow for personalized medicine
    Authors: BW Ellis, A Acun, UI Can, P Zorlutuna
    Biomicrofluidics, 2017;11(2):024105.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  115. Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols
    Authors: D Jeziorowsk, V Fontaine, C Jouve, E Villard, S Dussaud, D Akbar, V Letang, P Cervello, JM Itier, MP Pruniaux, JS Hulot
    Int J Mol Sci, 2017;18(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis
    Authors: NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry
    Cell Rep, 2017;20(7):1597-1608.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  117. Induced pluripotent stem cell-derived limbal epithelial cells (LiPSC) as a cellular alternative for in vitro ocular toxicity testing
    Authors: E Aberdam, I Petit, L Sangari, D Aberdam
    PLoS ONE, 2017;12(6):e0179913.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  118. A right-handed signalling pathway drives heart looping in vertebrates
    Authors: OH Ocaña, H Coskun, C Minguillón, P Murawala, EM Tanaka, J Galcerán, R Muñoz-Cháp, MA Nieto
    Nature, 2017;549(7670):86-90.
    Species: Zebrafish
    Sample Types: Whole Tissue
    Applications: Bioassay
  119. Direct comparison of distinct naive pluripotent states in human embryonic stem cells
    Authors: S Warrier, M Van der Je, G Duggal, L Tilleman, E Sutherland, J Taelman, M Popovic, S Lierman, S Chuva De S, A Van Soom, L Peelman, F Van Nieuwe, DIM De Coninck, B Menten, P Mestdagh, J Van de Som, D Deforce, P De Sutter, B Heindryckx
    Nat Commun, 2017;8(0):15055.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  120. Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells
    Nat Protoc, 2017;12(1):15-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics
    Authors: NG Kooreman, PE de Almeida, JP Stack, RV Nelakanti, S Diecke, NY Shao, RJ Swijnenbur, V Sanchez-Fr, E Matsa, C Liu, AJ Connolly, JF Hamming, PHA Quax, MA Brehm, DL Greiner, LD Shultz, JC Wu
    Cell Rep, 2017;20(8):1978-1990.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  122. DAN (NBL1) promotes collective neural crest migration by restraining uncontrolled invasion
    Authors: R McLennan, CM Bailey, LJ Schumacher, JM Teddy, JA Morrison, JC Kasemeier-, LA Wolfe, MM Gogol, RE Baker, PK Maini, PM Kulesa
    J. Cell Biol., 2017;216(10):3339-3354.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate
    Authors: AG Freire, A Waghray, F Soares-da-, TP Resende, DF Lee, CF Pereira, DS Nascimento, IR Lemischka, P Pinto-do-Ó
    Stem Cell Reports, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes
    Authors: G Yücel, Z Zhao, I El-Battraw, H Lan, S Lang, X Li, F Buljubasic, WH Zimmermann, L Cyganek, J Utikal, U Ravens, T Wieland, M Borggrefe, XB Zhou, I Akin
    Sci Rep, 2017;7(1):2935.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Integrated RNA-seq and DNase-seq analyses identify phenotype-specific BMP4 signaling in breast cancer
    Authors: M Ampuja, T Rantapero, A Rodriguez-, M Palmroth, EL Alarmo, M Nykter, A Kallioniem
    BMC Genomics, 2017;18(1):68.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Differentiation of cardiomyocytes and generation of human engineered heart tissue
    Authors: K Breckwoldt, D Letuffe-Br, I Mannhardt, T Schulze, B Ulmer, T Werner, A Benzin, B Klampe, MC Reinsch, S Laufer, A Shibamiya, M Prondzynsk, G Mearini, D Schade, S Fuchs, C Neuber, E Krämer, U Saleem, ML Schulze, ML Rodriguez, T Eschenhage, A Hansen
    Nat Protoc, 2017;12(6):1177-1197.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  127. Induction of senescence in primary glioblastoma cells by serum and TGF?
    Authors: R Kumar, A Gont, TJ Perkins, JEL Hanson, IAJ Lorimer
    Sci Rep, 2017;7(1):2156.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells
    Authors: Y Tachida, N Izumi, T Sakurai, H Kobayashi
    Biol Open, 2017;6(3):370-380.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Physico-electrochemical Characterization of Pluripotent Stem Cells during Self-Renewal or Differentiation by a Multi-modal Monitoring System
    Authors: K Low, LY Wong, M Maldonado, C Manjunath, CB Horner, M Perez, NV Myung, J Nam
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells
    Authors: A Taguchi, R Nishinakam
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Regulatory role of melatonin and BMP-4 in prolactin production by rat pituitary lactotrope GH3 cells
    Authors: K Ogura-Ochi, S Fujisawa, N Iwata, M Komatsubar, Y Nishiyama, N Tsukamoto-, K Inagaki, J Wada, F Otsuka
    Peptides, 2017;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Bone morphogenetic protein signaling mediated by ALK-2 and DLX2 regulates apoptosis in glioma-initiating cells
    Authors: E Raja, A Komuro, R Tanabe, S Sakai, Y Ino, N Saito, T Todo, M Morikawa, H Aburatani, D Koinuma, C Iwata, K Miyazono
    Oncogene, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling
    Authors: KB McCauley, F Hawkins, M Serra, DC Thomas, A Jacob, DN Kotton
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  134. Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
    Authors: F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier
    Nat Protoc, 2017;12(4):814-827.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Gelatin device for the delivery of growth factors involved in endochondral ossification
    Authors: LA Ahrens, D Vonwil, J Christense, VP Shastri
    PLoS ONE, 2017;12(4):e0175095.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1?
    Authors: KM Tsang, JS Hyun, KT Cheng, M Vargas, D Mehta, M Ushio-Fuka, L Zou, KV Pajcini, J Rehman, AB Malik
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  137. Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2
    Authors: P Scerbo, L Marchal, L Kodjabachi
    Elife, 2017;6(0):.
    Species: Xenopus
    Sample Types: In Vivo
    Applications: In Vivo
  138. GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency
    Authors: C Krendl, D Shaposhnik, V Rishko, C Ori, C Ziegenhain, S Sass, L Simon, NS Müller, T Straub, KE Brooks, SL Chavez, W Enard, FJ Theis, M Drukker
    Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  139. Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-?2 in Human TM Cells
    Authors: AA Mody, RJ Wordinger, AF Clark
    Invest. Ophthalmol. Vis. Sci, 2017;58(2):849-859.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  140. BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-? receptor type I ALK5
    Authors: LK Bollum, K Huse, MP Oksvold, B Bai, VI Hilden, L Forfang, SO Yoon, S Wälchli, EB Smeland, JH Myklebust
    PLoS ONE, 2017;12(5):e0177188.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  141. Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
    Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
    Cell Stem Cell, 2017;21(2):179-194.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  142. A pluripotent stem cell-based model for post-implantation human amniotic sac development
    Authors: Y Shao, K Taniguchi, RF Townshend, T Miki, DL Gumucio, J Fu
    Nat Commun, 2017;8(1):208.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  143. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling
    Stem Cell Res Ther, 2016;7(1):115.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  144. Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells
    Nat Commun, 2016;7(0):13602.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  145. Medial HOXA genes demarcate haematopoietic stem cell fate during human development
    Nat Cell Biol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves
    EBioMedicine, 2016;10(0):282-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  147. In�Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts
    Authors: S Kadota, L Pabon, H Reinecke, CE Murry
    Stem Cell Reports, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker
    Nat. Biotechnol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Automated image analysis with the potential for process quality control applications in stem cell maintenance and differentiation
    Authors: Robert Thomas
    Biotechnol. Prog., 2016;32(1):215-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  150. Comparison between pediatric and adult adipose mesenchymal stromal cells
    Authors: Olivier Abbo
    Cytotherapy, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  151. The Binding of the Bone Morphogenetic Protein Antagonist Gremlin to Kidney Heparan Sulfate: Such Binding is not Essential for BMP Antagonism
    Authors: Arnold Junior Tatsinkam
    Int. J. Biochem. Cell Biol, 2016;0(0):.
    Applications: Bioassay
  152. Yes-Associated Protein Inhibits Transcription of Myocardin and Attenuates Differentiation of Vascular Smooth Muscle Cell from Cardiovascular Progenitor Cell Lineage
    Stem Cells, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication
    PLoS ONE, 2016;11(12):e0168334.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  154. BMP4 Signaling Is Able to Induce an Epithelial-Mesenchymal Transition-Like Phenotype in Barrett's Esophagus and Esophageal Adenocarcinoma through Induction of SNAIL2.
    Authors: Christine Kestens, Peter D Siersema, G Johan A Offerhaus, Jantine W P M Van Baal
    PLoS ONE, 2016;0(0):1932-6203.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease
    Authors: Mariko Horii
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Microfabric Vessels for Embryoid Body Formation and Rapid Differentiation of Pluripotent Stem Cells
    Sci Rep, 2016;6(0):31063.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Coupling switch of P2Y-IP3 receptors mediates differential Ca(2+) signaling in human embryonic stem cells and derived cardiovascular progenitor cells
    Authors: Huang-Tian Yang
    Purinergic Signal., 2016;12(3):465-78.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes
    Stem Cells Transl Med, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  159. ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation
    Stem Cell Res, 2016;17(2):222-227.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer.
    Authors: Hermanson D, Bendzick L, Pribyl L, McCullar V, Vogel R, Miller J, Geller M, Kaufman D
    Stem Cells, 2016;34(1):93-101.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  161. A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells
    EMBO Mol Med, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  162. MxA Is a Novel Regulator of Endosome-Associated Transcriptional Signaling by Bone Morphogenetic Proteins 4 and 9 (BMP4 and BMP9)
    PLoS ONE, 2016;11(11):e0166382.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes
    Stem Cell Reports, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway
    Cell Biosci, 2016;6(1):50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  165. A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients
    Elife, 2016;5(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  166. The involvement of protein kinase C-? in isoflurane induced preconditioning of human embryonic stem cell--derived Nkx2.5(+) cardiac progenitor cells
    Authors: IA Song, AY Oh, JH Kim, YM Choi, YT Jeon, JH Ryu, JW Hwang
    BMC Anesthesiol, 2016;16(0):13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
    Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
    Nat. Med., 2016;22(12):1421-1427.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Calreticulin is a secreted BMP antagonist, expressed in Hensen's node during neural induction
    Authors: Irene De Almeida
    Dev. Biol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Bovine ovarian stem cells differentiate into germ cells and oocyte-like structures after culture in vitro
    Authors: G B de Souza
    Reprod. Domest. Anim, 2016;0(0):.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Five colour variants of bright luminescent protein for real-time multicolour bioimaging
    Nat Commun, 2016;7(0):13718.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Oligodendroglial maturation is dependent on intracellular protein shuttling.
    Authors: Gottle P, Sabo J, Heinen A, Venables G, Torres K, Tzekova N, Parras C, Kremer D, Hartung H, Cate H, Kury P
    J Neurosci, 2015;35(3):906-19.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  172. Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells.
    Authors: Lee J, Graham M, Collins T, Lee J, Hong S, McNicol A, Shapovalova Z, Bhatia M
    Stem Cells, 2015;33(4):1142-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Additive Effects of Retinoic Acid (RA) and Bone Morphogenetic Protein 4 (BMP-4) Apoptosis Signaling in Retinoblastoma Cell Lines.
    Authors: Muller P, Doliva R, Busch M, Philippeit C, Stephan H, Dunker N
    PLoS ONE, 2015;10(7):e0131467.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  174. Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.
    Authors: Gori J, Butler J, Chan Y, Chandrasekaran D, Poulos M, Ginsberg M, Nolan D, Elemento O, Wood B, Adair J, Rafii S, Kiem H
    J Clin Invest, 2015;125(3):1243-54.
    Species: Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  175. Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1.
    Authors: Majumder A, Syed K, Joseph S, Scambler P, Dutta D
    J Biol Chem, 2015;290(21):13053-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  176. Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis.
    Authors: Kim M, Horst A, Blinka S, Stamm K, Mahnke D, Schuman J, Gundry R, Tomita-Mitchell A, Lough J
    PLoS ONE, 2015;10(2):e0118670.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Alternative Routes to Induce Naive Pluripotency in Human Embryonic Stem Cells.
    Authors: Duggal G, Warrier S, Ghimire S, Broekaert D, Van der Jeught M, Lierman S, Deroo T, Peelman L, Van Soom A, Cornelissen R, Menten B, Mestdagh P, Vandesompele J, Roost M, Slieker R, Heijmans B, Deforce D, De Sutter P, de Sousa Lopes S, Heindryckx B
    Stem Cells, 2015;33(9):2686-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Improved hematopoietic differentiation efficiency of gene-corrected beta-thalassemia induced pluripotent stem cells by CRISPR/Cas9 system.
    Authors: Song B, Fan Y, He W, Zhu D, Niu X, Wang D, Ou Z, Luo M, Sun X
    Stem Cells Dev, 2015;24(9):1053-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  179. The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells.
    Authors: Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D'Souza S, Snoeck H
    Nat Protoc, 2015;10(3):413-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Enhanced Electrical Integration of Engineered Human Myocardium via Intramyocardial versus Epicardial Delivery in Infarcted Rat Hearts.
    Authors: Gerbin K, Yang X, Murry C, Coulombe K
    PLoS ONE, 2015;10(7):e0131446.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells.
    Authors: Wong, Amy P, Chin, Stephani, Xia, Sunny, Garner, Jodi, Bear, Christin, Rossant, Janet
    Nat Protoc, 2015;10(3):363-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  182. BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells.
    Authors: Kim J, Kurie J, Ahn Y
    Mol Cancer, 2015;14(1):173.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes.
    Authors: Maury Y, Come J, Piskorowski R, Salah-Mohellibi N, Chevaleyre V, Peschanski M, Martinat C, Nedelec S
    Nat Biotechnol, 2015;33(1):89-96.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Constitutive activation of myosin-dependent contractility sensitizes glioma tumor-initiating cells to mechanical inputs and reduces tissue invasion.
    Authors: Wong S, Ulrich T, Deleyrolle L, MacKay J, Lin J, Martuscello R, Jundi M, Reynolds B, Kumar S
    Cancer Res, 2015;75(6):1113-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Cytoskeletal Reorganization Drives Mesenchymal Condensation and Regulates Downstream Molecular Signaling.
    Authors: Ray P, Chapman S
    PLoS ONE, 2015;10(8):e0134702.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: Bioassay
  186. A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face.
    Authors: Hu D, Young N, Li X, Xu Y, Hallgrimsson B, Marcucio R
    Development, 2015;142(3):567-74.
    Species: Chicken
    Sample Types: Whole Organism
    Applications: In Vivo
  187. A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology.
    Authors: Tate C, Mc Entire J, Pallini R, Vakana E, Wyss L, Blosser W, Ricci-Vitiani L, D'Alessandris Q, Morgante L, Giannetti S, Larocca L, Todaro M, Benfante A, Colorito M, Stassi G, De Maria R, Rowlinson S, Stancato L
    PLoS ONE, 2015;10(4):e0125697.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Increased culture density is linked to decelerated proliferation, prolonged G1 phase, and enhanced propensity for differentiation of self-renewing human pluripotent stem cells.
    Authors: Wu J, Fan Y, Tzanakakis E
    Stem Cells Dev, 2015;24(7):892-903.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Transcription factor binding dynamics during human ES cell differentiation.
    Authors: Tsankov, Alexande, Gu, Hongcang, Akopian, Veronika, Ziller, Michael, Donaghey, Julie, Amit, Ido, Gnirke, Andreas, Meissner, Alexande
    Nature, 2015;518(7539):344-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Heightened potency of human pluripotent stem cell lines created by transient BMP4 exposure.
    Authors: Yang Y, Adachi K, Sheridan M, Alexenko A, Schust D, Schulz L, Ezashi T, Roberts R
    Proc Natl Acad Sci U S A, 2015;112(18):E2337-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  191. GSK3beta inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells.
    Authors: Kitajima K, Nakajima M, Kanokoda M, Kyba M, Dandapat A, Tolar J, Saito M, Toyoda M, Umezawa A, Hara T
    Exp Hematol, 2015;44(1):68-74.e10.
  192. Generation of articular chondrocytes from human pluripotent stem cells.
    Authors: Craft A, Rockel J, Nartiss Y, Kandel R, Alman B, Keller G
    Nat Biotechnol, 2015;33(6):638-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Transcriptional profiling of ectoderm specification to keratinocyte fate in human embryonic stem cells.
    Authors: Tadeu A, Lin S, Hou L, Chung L, Zhong M, Zhao H, Horsley V
    PLoS ONE, 2015;10(4):e0122493.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile.
    Authors: Sugawa F, Arauzo-Bravo M, Yoon J, Kim K, Aramaki S, Wu G, Stehling M, Psathaki O, Hubner K, Scholer H
    EMBO J, 2015;34(8):1009-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  195. Bone morphogenetic proteins are mediators of luteolysis in the human corpus luteum.
    Authors: Nio-Kobayashi J, Trendell J, Giakoumelou S, Boswell L, Nicol L, Kudo M, Sakuragi N, Iwanaga T, Duncan W
    Endocrinology, 2015;156(4):1494-503.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  196. Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells.
    Authors: Iyer D, Gambardella L, Bernard W, Serrano F, Mascetti V, Pedersen R, Talasila A, Sinha S
    Development, 2015;142(8):1528-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Inner ear hair cell-like cells from human embryonic stem cells.
    Authors: Ronaghi, Mohammad, Nasr, Marjan, Ealy, Megan, Durruthy-Durruthy, Robert, Waldhaus, Joerg, Diaz, Giovanni, Joubert, Lydia-Ma, Oshima, Kazuo, Heller, Stefan
    Stem Cells Dev, 2014;23(11):1275-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  198. Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression.
    Authors: Laperrousaz B, Jeanpierre S, Sagorny K, Voeltzel T, Ramas S, Kaniewski B, Ffrench M, Salesse S, Nicolini F, Maguer-Satta V
    Blood, 2014;122(23):3767-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome.
    Authors: Kobayashi, Junko, Yoshida, Masashi, Tarui, Suguru, Hirata, Masataka, Nagai, Yusuke, Kasahara, Shingo, Naruse, Keiji, Ito, Hiroshi, Sano, Shunji, Oh, Hidemasa
    PLoS ONE, 2014;9(7):e102796.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Efficient generation of lung and airway epithelial cells from human pluripotent stem cells.
    Authors: Huang, Sarah X, Islam, Mohammad, O'Neill, John, Hu, Zheng, Yang, Yong-Gua, Chen, Ya-Wen, Mumau, Melanie, Green, Michael, Vunjak-Novakovic, Gordana, Bhattacharya, Jahar, Snoeck, Hans-Wil
    Nat Biotechnol, 2014;32(1):84-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  201. Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant.
    Authors: Takebe, Takanori, Zhang, Ran-Ran, Koike, Hiroyuki, Kimura, Masaki, Yoshizawa, Emi, Enomura, Masahiro, Koike, Naoto, Sekine, Keisuke, Taniguchi, Hideki
    Nat Protoc, 2014;9(2):396-409.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Real-time discrimination between proliferation and neuronal and astroglial differentiation of human neural stem cells.
    Authors: Lee, Rimi, Kim, Il-Sun, Han, Nalae, Yun, Seokhwan, Park, Kook In, Yoo, Kyung-Hw
    Sci Rep, 2014;4(0):6319.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  203. NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation.
    Authors: Mahadevan, Sangeeth, Wen, Shu, Wan, Ying-Woo, Peng, Hsiu-Hue, Otta, Subhendu, Liu, Zhandong, Iacovino, Michelin, Mahen, Elisabet, Kyba, Michael, Sadikovic, Bekim, Van den Veyver, Ignatia
    Hum Mol Genet, 2014;23(3):706-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  204. The role of Hath6, a newly identified shear-stress-responsive transcription factor, in endothelial cell differentiation and function.
    Authors: Fang F, Wasserman S, Torres-Vazquez J, Weinstein B, Cao F, Li Z, Wilson K, Yue W, Wu J, Xie X, Pei X
    J Cell Sci, 2014;127(0):1428-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  205. High efficient differentiation of functional hepatocytes from porcine induced pluripotent stem cells.
    Authors: Ao, Ying, Mich-Basso, Jocelyn, Lin, Bo, Yang, Lei
    PLoS ONE, 2014;9(6):e100417.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  206. Ligand- and stage-dependent divergent functions of BMP signaling in the differentiation of embryonic skeletogenic progenitors in vitro.
    Authors: Lorda-Diez C, Montero J, Choe S, Garcia-Porrero J, Hurle J
    J Bone Miner Res, 2014;29(3):735-48.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Identification and purification of human induced pluripotent stem cell-derived atrial-like cardiomyocytes based on sarcolipin expression.
    Authors: Josowitz, Rebecca, Lu, Jia, Falce, Christin, D'Souza, Sunita L, Wu, Meng, Cohen, Ninette, Dubois, Nicole C, Zhao, Yong, Sobie, Eric A, Fishman, Glenn I, Gelb, Bruce D
    PLoS ONE, 2014;9(7):e101316.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium.
    Authors: Turnbull I, Karakikes I, Serrao G, Backeris P, Lee J, Xie C, Senyei G, Gordon R, Li R, Akar F, Hajjar R, Hulot J, Costa K
    FASEB J, 2014;28(2):644-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  209. MicroRNA-155 controls RB phosphorylation in normal and malignant B lymphocytes via the noncanonical TGF-beta1/SMAD5 signaling module.
    Authors: Jiang D, Aguiar R
    Blood, 2014;123(1):86-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  210. BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity.
    Authors: Cao Y, Slaney C, Bidwell B, Parker B, Johnstone C, Rautela J, Eckhardt B, Anderson R
    Cancer Res, 2014;74(18):5091-102.
  211. Functional assessment of hematopoietic niche cells derived from human embryonic stem cells.
    Authors: Ferrell, Patrick, Hexum, Melinda, Kopher, Ross A, Lepley, Michael, Gussiaas, Amanda, Kaufman, Dan S
    Stem Cells Dev, 2014;23(12):1355-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Suppression of the SOX2 neural effector gene by PRDM1 promotes human germ cell fate in embryonic stem cells.
    Authors: Lin, I-Ying, Chiu, Feng-Lan, Yeang, Chen-Hsi, Chen, Hsin-Fu, Chuang, Ching-Yu, Yang, Shii-Yi, Hou, Pei-Shan, Sintupisut, Nardnisa, Ho, Hong-Ner, Kuo, Hung-Chi, Lin, Kuo-I
    Stem Cell Reports, 2014;2(2):189-204.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling.
    Authors: Jakobsen R, Ostrup E, Zhang X, Mikkelsen T, Brinchmann J
    PLoS ONE, 2014;9(5):e96615.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. CCAAT/enhancer binding protein-mediated regulation of TGFbeta receptor 2 expression determines the hepatoblast fate decision.
    Authors: Takayama K, Kawabata K, Nagamoto Y, Inamura M, Ohashi K, Okuno H, Yamaguchi T, Tashiro K, Sakurai F, Hayakawa T, Okano T, Furue M, Mizuguchi H
    Development, 2014;141(1):91-100.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  215. Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification.
    Authors: Culbert A, Chakkalakal S, Theosmy E, Brennan T, Kaplan F, Shore E
    Stem Cells, 2014;32(5):1289-300.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  216. Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice.
    Authors: Zhang Y, Liu J, Tian X, Wong W, Chen Y, Wang L, Luo J, Cheang W, Lau C, Kwan K, Wang N, Yao X, Huang Y
    Arterioscler Thromb Vasc Biol, 2014;34(1):152-9.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  217. Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin.
    Authors: Olsen O, Wader K, Misund K, Vatsveen T, Ro T, Mylin A, Turesson I, Stordal B, Moen S, Standal T, Waage A, Sundan A, Holien T
    Blood Cancer J, 2014;4(0):e196.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  218. A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear.
    Authors: Mann Z, Thiede B, Chang W, Shin J, May-Simera H, Lovett M, Corwin J, Kelley M
    Nat Commun, 2014;5(0):3839.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells.
    Authors: Taguchi A, Kaku Y, Ohmori T, Sharmin S, Ogawa M, Sasaki H, Nishinakamura R
    Cell Stem Cell, 2014;14(1):53-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Focal transplantation of human iPSC-derived glial-rich neural progenitors improves lifespan of ALS mice.
    Authors: Kondo T, Funayama M, Tsukita K, Hotta A, Yasuda A, Nori S, Kaneko S, Nakamura M, Takahashi R, Okano H, Yamanaka S, Inoue H
    Stem Cell Reports, 2014;3(2):242-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Generation of folliculogenic human epithelial stem cells from induced pluripotent stem cells.
    Authors: Yang, Ruifeng, Zheng, Ying, Burrows, Michelle, Liu, Shujing, Wei, Zhi, Nace, Arben, Guo, Wei, Kumar, Suresh, Cotsarelis, George, Xu, Xiaowei
    Nat Commun, 2014;5(0):3071.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  222. Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa.
    Authors: Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, Keene D, Liu L, Osborn M, Lund T, Blazar B, Wagner J
    J Invest Dermatol, 2014;134(5):1246-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  223. Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm.
    Authors: Takahashi K, Tanabe K, Ohnuki M, Narita M, Sasaki A, Yamamoto M, Nakamura M, Sutou K, Osafune K, Yamanaka S
    Nat Commun, 2014;5(0):3678.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling.
    Authors: Kim W, Zhu Y, Deng Q, Chin C, He C, Grieco A, Dravid G, Parekh C, Hollis R, Lane T, Bouhassira E, Kohn D, Crooks G
    Stem Cells, 2014;32(6):1503-14.
  225. Broad T-cell receptor repertoire in T-lymphocytes derived from human induced pluripotent stem cells.
    Authors: Chang C, Lai Y, Lamb L, Townes T
    PLoS ONE, 2014;9(5):e97335.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  226. Cobalt protoporphyrin pretreatment protects human embryonic stem cell-derived cardiomyocytes from hypoxia/reoxygenation injury in vitro and increases graft size and vascularization in vivo.
    Authors: Luo J, Weaver M, Cao B, Dennis J, Van Biber B, Laflamme M, Allen M
    Stem Cells Transl Med, 2014;3(6):734-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Derivation and expansion of PAX7-positive muscle progenitors from human and mouse embryonic stem cells.
    Authors: Shelton M, Metz J, Liu J, Carpenedo R, Demers S, Stanford W, Skerjanc I
    Stem Cell Reports, 2014;3(3):516-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Enzyme-free passage of human pluripotent stem cells by controlling divalent cations.
    Authors: Ohnuma, Kiyoshi, Fujiki, Ayaka, Yanagihara, Kana, Tachikawa, Saoko, Hayashi, Yohei, Ito, Yuzuru, Onuma, Yasuko, Chan, Techuan, Michiue, Tatsuo, Furue, Miho K, Asashima, Makoto
    Sci Rep, 2014;4(0):4646.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Characterization of stem-like cells in mucoepidermoid tracheal paediatric tumor.
    Authors: Lim M, Ooi B, Jungebluth P, Sjoqvist S, Hultman I, Lemon G, Gustafsson Y, Asmundsson J, Baiguera S, Douagi I, Gilevich I, Popova A, Haag J, Rodriguez A, Lim J, Lieden A, Nordenskjold M, Alici E, Baker D, Unger C, Luedde T, Vassiliev I, Inzunza J, Ahrlund-Richter L, Macchiarini P
    PLoS ONE, 2014;9(9):e107712.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  230. CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis.
    Authors: Todaro M, Gaggianesi M, Catalano V, Benfante A, Iovino F, Biffoni M, Apuzzo T, Sperduti I, Volpe S, Cocorullo G, Gulotta G, Dieli F, De Maria R, Stassi G
    Cell Stem Cell, 2014;14(3):342-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  231. BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells.
    Authors: Srikanth, Maya, Kim, Juno, Das, Sunit, Kessler, John A
    Mol Cancer Res, 2014;12(2):283-94.
  232. BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors.
    Authors: Tsuchida, R, Osawa, T, Wang, F, Nishii, R, Das, B, Tsuchida, S, Muramatsu, M, Takahashi, T, Inoue, T, Wada, Y, Minami, T, Yuasa, Y, Shibuya, M
    Oncogene, 2014;33(29):3803-11.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Twisted gastrulation, a BMP antagonist, exacerbates podocyte injury.
    Authors: Yamada, Sachiko, Nakamura, Jin, Asada, Misako, Takase, Masayuki, Matsusaka, Taiji, Iguchi, Taku, Yamada, Ryo, Tanaka, Mari, Higashi, Atsuko Y, Okuda, Tomohiko, Asada, Nariaki, Fukatsu, Atsushi, Kawachi, Hiroshi, Graf, Daniel, Muso, Eri, Kita, Toru, Kimura, Takeshi, Pastan, Ira, Economides, Aris N, Yanagita, Motoko
    PLoS ONE, 2014;9(2):e89135.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers.
    Authors: Lam A, Freedman B, Morizane R, Lerou P, Valerius M, Bonventre J
    J Am Soc Nephrol, 2014;25(6):1211-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  235. HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin.
    Authors: Watanabe, Hitoshi, Takayama, Kazuo, Inamura, Mitsuru, Tachibana, Masashi, Mimura, Natsumi, Katayama, Kazufumi, Tashiro, Katsuhis, Nagamoto, Yasuhito, Sakurai, Fuminori, Kawabata, Kenji, Furue, Miho Kus, Mizuguchi, Hiroyuki
    PLoS ONE, 2014;9(3):e90791.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis.
    Authors: Morishima, Tatsuya, Watanabe, Ken-ichi, Niwa, Akira, Hirai, Hideyo, Saida, Satoshi, Tanaka, Takayuki, Kato, Itaru, Umeda, Katsutsu, Hiramatsu, Hidefumi, Saito, Megumu K, Matsubara, Kousaku, Adachi, Souichi, Kobayashi, Masao, Nakahata, Tatsutos, Heike, Toshio
    Haematologica, 2014;99(1):19-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  237. SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion.
    Authors: Cabrera-Sharp V, Read J, Richardson S, Kowalski A, Antczak D, Cartwright J, Mukherjee A, de Mestre A
    Endocrinology, 2014;155(8):3054-64.
    Species: Equine
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Molecular beacon-enabled purification of living cells by targeting cell type-specific mRNAs.
    Authors: Wile B, Ban K, Yoon Y, Bao G
    Nat Protoc, 2014;9(10):2411-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  239. Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs.
    Authors: Park, Chul-Yon, Kim, Jungeun, Kweon, Jiyeon, Son, Jeong Sa, Lee, Jae Souk, Yoo, Jeong-Eu, Cho, Sung-Rae, Kim, Jong-Hoo, Kim, Jin-Soo, Kim, Dong-Woo
    Proc Natl Acad Sci U S A, 2014;111(25):9253-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies.
    Authors: Dominguez, Antonia, Chiang, H Rosari, Sukhwani, Meena, Orwig, Kyle E, Reijo Pera, Renee A
    Sci Rep, 2014;4(0):6432.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  241. Role of bone morphogenetic protein 4 in the differentiation of brown fat-like adipocytes.
    Authors: Xue, Ruidan, Wan, Yun, Zhang, Shuo, Zhang, Qiongyue, Ye, Hongying, Li, Yiming
    Am J Physiol Endocrinol Metab, 2014;306(4):E363-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  242. Identification of small molecule activators of BMP signaling.
    Authors: Vrijens K, Lin W, Cui J, Farmer D, Low J, Pronier E, Zeng F, Shelat A, Guy K, Taylor M, Chen T, Roussel M
    PLoS ONE, 2013;8(3):e59045.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  243. KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.
    Authors: Goldman O, Han S, Sourisseau M, Dziedzic N, Hamou W, Corneo B, D'Souza S, Sato T, Kotton D, Bissig K, Kalir T, Jacobs A, Evans T, Evans M, Gouon-Evans V
    Cell Stem Cell, 2013;12(6):748-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  244. Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal.
    Authors: Wang Y, Xu Z, Jiang J, Xu C, Kang J, Xiao L, Wu M, Xiong J, Guo X, Liu H
    Dev Cell, 2013;25(1):69-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  245. BMP4 is a peripherally-derived factor for motor neurons and attenuates glutamate-induced excitotoxicity in vitro.
    Authors: Chou H, Lai D, Huang C, McLennan I, Wang H, Wang P
    PLoS ONE, 2013;8(3):e58441.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  246. Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.
    Authors: Pick M, Azzola L, Osborne E, Stanley E, Elefanty A
    PLoS ONE, 2013;8(2):e55530.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  247. Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays.
    Authors: Navarrete E, Liang P, Lan F, Sanchez-Freire V, Simmons C, Gong T, Sharma A, Burridge P, Patlolla B, Lee A, Wu H, Beygui R, Wu S, Robbins R, Bers D, Wu J
    Circulation, 2013;128(11):S3-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  248. Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation.
    Authors: Talavera-Adame, Dodanim, Gupta, Ankur, Kurtovic, Silvia, Chaiboonma, Kira L, Arumugaswami, Vaithili, Dafoe, Donald C
    Stem Cells Dev, 2013;22(24):3252-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  249. Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue.
    Authors: Deschaseaux F, Gaillard J, Langonne A, Chauveau C, Naji A, Bouacida A, Rosset P, Heymann D, De Pinieux G, Rouas-Freiss N, Sensebe L
    FASEB J, 2013;27(8):2977-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.
    Authors: Doulatov S, Vo L, Chou S, Kim P, Arora N, Li H, Hadland B, Bernstein I, Collins J, Zon L, Daley G
    Cell Stem Cell, 2013;13(4):459-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.
    Authors: Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel C, Hoing S, Moritz S, Parga J, Wagner L, Bruder J, Wu G, Schmid B, Ropke A, Klingauf J, Schwamborn J, Gasser T, Scholer H, Sterneckert J
    PLoS ONE, 2013;8(3):e59252.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  252. A human Dravet syndrome model from patient induced pluripotent stem cells.
    Authors: Higurashi N, Uchida T, Lossin C, Misumi Y, Okada Y, Akamatsu W, Imaizumi Y, Zhang B, Nabeshima K, Mori M, Katsurabayashi S, Shirasaka Y, Okano H, Hirose S
    Mol Brain, 2013;6(0):19.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  253. A low-molecular-weight compound K7174 represses hepcidin: possible therapeutic strategy against anemia of chronic disease.
    Authors: Fujiwara, Tohru, Ikeda, Takashi, Nagasaka, Yuki, Okitsu, Yoko, Katsuoka, Yuna, Fukuhara, Noriko, Onishi, Yasushi, Ishizawa, Kenichi, Ichinohasama, Ryo, Tomosugi, Naohisa, Harigae, Hideo
    PLoS ONE, 2013;8(9):e75568.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  254. Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells.
    Authors: White M, Rufaihah A, Liu L, Ghebremariam Y, Ivey K, Cooke J, Srivastava D
    Stem Cells, 2013;31(1):92-103.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  255. Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential.
    Authors: Duggal G, Heindryckx B, Warrier S, O'Leary T, Van der Jeught M, Lierman S, Vossaert L, Deroo T, Deforce D, Chuva de Sousa Lopes S, De Sutter P
    Stem Cells Dev, 2013;22(23):3141-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  256. Blockade of Smad signaling by 3'-deoxyadenosine: a mechanism for its anti-fibrotic potential.
    Authors: Gu L, Johno H, Nakajima S, Kato H, Takahashi S, Katoh R, Kitamura M
    Lab Invest, 2013;93(4):450-61.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  257. Production of hepatocyte-like cells from human pluripotent stem cells.
    Authors: Hannan, Nicholas, Segeritz, Charis-P, Touboul, Thomas, Vallier, Ludovic
    Nat Protoc, 2013;8(2):430-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  258. Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production.
    Authors: Glister C, Satchell L, Bathgate R, Wade J, Dai Y, Ivell R, Anand-Ivell R, Rodgers R, Knight P
    Proc Natl Acad Sci U S A, 2013;110(15):E1426-35.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
    Authors: Liang, Ping, Lan, Feng, Lee, Andrew S, Gong, Tingyu, Sanchez-Freire, Veronica, Wang, Yongming, Diecke, Sebastia, Sallam, Karim, Knowles, Joshua W, Wang, Paul J, Nguyen, Patricia, Bers, Donald M, Robbins, Robert C, Wu, Joseph C
    Circulation, 2013;127(16):1677-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Generation of human induced pluripotent stem cells using epigenetic regulators reveals a germ cell-like identity in partially reprogrammed colonies.
    Authors: Goyal, Akshi, Chavez, Shawn L, Reijo Pera, Renee A
    PLoS ONE, 2013;8(12):e82838.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  261. Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes.
    Authors: Takayama K, Nagamoto Y, Mimura N, Tashiro K, Sakurai F, Tachibana M, Hayakawa T, Kawabata K, Mizuguchi H
    Stem Cell Reports, 2013;1(4):322-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  262. Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells.
    Authors: Lee J, Sugiyama T, Liu Y, Wang J, Gu X, Lei J, Markmann J, Miyazaki S, Miyazaki J, Szot G, Bottino R, Kim S
    Elife, 2013;2(0):e00940.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells.
    Authors: Kohler, Erin E, Wary, Kishore, Li, Fei, Chatterjee, Ishita, Urao, Norifumi, Toth, Peter T, Ushio-Fukai, Masuko, Rehman, Jalees, Park, Changwon, Malik, Asrar B
    PLoS ONE, 2013;8(12):e85549.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  264. TGF-beta-induced apoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD20.
    Authors: Kawabata K, Ehata S, Komuro A, Takeuchi K, Miyazono K
    Oncogene, 2013;32(16):2096-106.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium.
    Authors: Yao Y, Jumabay M, Ly A, Radparvar M, Wang AH, Abdmaulen R, Bostrom KI
    Blood, 2012;119(21):5037-47.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Bioassay
  266. Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs).
    Authors: Wu, Qifang, Sun, Chia Chi, Lin, Herbert, Babitt, Jodie L
    PLoS ONE, 2012;7(9):e46307.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Surface Plasmon Resonance
  267. The endothelial cell line bEnd.3 maintains human pluripotent stem cells.
    Authors: Joubin, Katherin, Richardson, Amelia, Novoa, Natalia, Tu, Edmund, Tomishima, Mark J
    Stem Cells Dev, 2012;21(12):2312-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  268. The hedgehog system in ovarian follicles of cattle selected for twin ovulations and births: evidence of a link between the IGF and hedgehog systems.
    Authors: Aad, Pauline, Echternkamp, Sherrill, Sypherd, David D, Schreiber, Nicole B, Spicer, Leon J
    Biol Reprod, 2012;87(4):79.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  269. Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion.
    Authors: Kim M, Yoon S, Lee S
    PLoS ONE, 2012;7(4):e35100.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Binding Assay
  270. Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma.
    Authors: Huse K, Bakkebo M, Walchli S, Oksvold M, Hilden V, Forfang L, Bredahl M, Liestol K, Alizadeh A, Smeland E, Myklebust J
    PLoS ONE, 2012;7(10):e46117.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  271. Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility.
    Authors: Cheung C, Bernardo AS, Trotter MW
    Nat. Biotechnol., 2012;30(2):165-73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
    Gene Ther, 2012;19(10):1035-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  273. Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion.
    Authors: Pereira P, Dobreva M, Maas E, Cornelis F, Moya I, Umans L, Verfaillie C, Camus A, de Sousa Lopes S, Huylebroeck D, Zwijsen A
    Development, 2012;139(18):3343-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  274. A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors.
    Authors: Niwa A, Heike T, Umeda K
    PLoS ONE, 2011;6(7):e22261.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  275. A novel role for an RNA polymerase III subunit POLR3G in regulating pluripotency in human embryonic stem cells.
    Authors: Wong RC, Pollan S, Fong H, Ibrahim A, Smith EL, Ho M, Laslett AL, Donovan PJ
    Stem Cells, 2011;29(10):1517-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  276. Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7.
    Authors: Huse K, Bakkebo M, Oksvold MP, Forfang L, Hilden VI, Stokke T, Smeland EB, Myklebust JH
    Eur. J. Immunol., 2011;41(11):3135-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  277. Sertoli cell-conditioned medium induces germ cell differentiation in human embryonic stem cells.
    Authors: Geens M, Sermon KD
    J. Assist. Reprod. Genet., 2011;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome).
    Authors: Tolar J, Park I, Xia L, Lees C, Peacock B, Webber B, McElmurry R, Eide C, Orchard P, Kyba M, Osborn M, Lund T, Wagner J, Daley G, Blazar B
    Blood, 2011;117(3):839-47.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  279. Down-regulation of Kruppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-{beta} and Bone Morphogenetic Protein 4.
    Authors: Davis-Dusenbery BN, Chan MC, Reno KE, Weisman AS, Layne MD, Lagna G, Hata A
    J. Biol. Chem., 2011;286(32):28097-110.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  280. Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma.
    Authors: Maegdefrau U, Arndt S, Kivorski G, Hellerbrand C, Bosserhoff AK
    Lab. Invest., 2011;91(11):1615-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  281. Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth.
    Authors: Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV
    J. Biol. Chem., 2011;286(34):30034-46.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Surface Plasmon Resonance
  282. A small peptide modeled after the NRAGE repeat domain inhibits XIAP-TAB1-TAK1 signaling for NF-kappaB activation and apoptosis in P19 cells.
    Authors: Rochira JA, Matluk NN, Adams TL, Karaczyn AA, Oxburgh L, Hess ST, Verdi JM
    PLoS ONE, 2011;6(7):e20659.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  283. Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals.
    Authors: Zhang Q, Jiang J, Han P, Yuan Q, Zhang J, Zhang X, Xu Y, Cao H, Meng Q, Chen L, Tian T, Wang X, Li P, Hescheler J, Ji G, Ma Y
    Cell Res., 2011;21(4):579-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  284. BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling pathway.
    Authors: Stewart A, Guan H, Yang K
    J. Cell. Physiol., 2010;223(3):658-66.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  285. The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain.
    Authors: Martino MM, Hubbell JA
    FASEB J., 2010;24(12):4711-21.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Surface Plasmon Resonance
  286. Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state.
    Authors: Lanner F, Lee KL, Sohl M, Holmborn K, Yang H, Wilbertz J, Poellinger L, Rossant J, Farnebo F
    Stem Cells, 2010;28(2):191-200.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  287. Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells.
    Authors: Roelandt P, Pauwelyn KA, Sancho-Bru P
    PLoS ONE, 2010;5(8):e12101.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  288. SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
    Authors: Chng Z, Teo A, Pedersen RA, Vallier L
    Cell Stem Cell, 2010;6(1):59-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  289. Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis.
    Authors: Rai D, Kim SW, McKeller MR
    Proc. Natl. Acad. Sci. U.S.A., 2010;107(7):3111-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Bone morphogenetic proteins and receptors are over-expressed in bone-marrow cells of multiple myeloma patients and support myeloma cells by inducing ID genes.
    Authors: Grcevic D, Kusec R, Kovacic N, Lukic A, Lukic IK, Ivcevic S, Nemet D, Seiwerth RS, Ostojic SK, Croucher PI, Marusic A
    Leuk. Res., 2010;34(6):742-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  291. A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
    Authors: Klim JR, Li L, Wrighton PJ
    Nat. Methods, 2010;7(12):989-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  292. Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases.
    Authors: Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW
    Proc. Natl. Acad. Sci. U.S.A., 2009;106(24):9826-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  293. Postinjury niches induce temporal shifts in progenitor fates to direct lesion repair after spinal cord injury.
    Authors: Sellers DL, Maris DO, Horner PJ
    J. Neurosci., 2009;29(20):6722-33.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  294. Scaffold-free human cardiac tissue patch created from embryonic stem cells.
    Authors: Stevens KR, Pabon L, Muskheli V
    Tissue Eng Part A, 2009;15(6):1211-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  295. A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum.
    Authors: Herrera B, Inman GJ,
    BMC Cell Biol., 2009;10(0):20.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  296. Fibroblast growth factors and epidermal growth factor cooperate with oocyte-derived members of the TGFbeta superfamily to regulate Spry2 mRNA levels in mouse cumulus cells.
    Authors: Sugiura K, Su YQ, Li Q, Wigglesworth K, Matzuk MM, Eppig JJ
    Biol. Reprod., 2009;81(5):833-41.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  297. Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.
    Authors: Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K
    Stem Cells, 2009;27(2):341-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells.
    Authors: Tanno T, Porayette P, Sripichai O, Noh SJ, Byrnes C, Bhupatiraju A, Lee YT, Goodnough JB, Harandi O, Ganz T, Paulson RF, Miller JL
    Blood, 2009;114(1):181-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Signaling hierarchy regulating human endothelial cell development.
    Authors: Kelly MA, Hirschi KK
    Arterioscler. Thromb. Vasc. Biol., 2009;29(5):718-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  300. GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses.
    Authors: Levine AJ, Levine ZJ, Brivanlou AH
    Dev. Biol., 2009;325(1):43-8.
    Species: Xenopus
    Sample Types: Whole Cells
    Applications: Bioassay
  301. Regulation of bone morphogenetic protein signalling in human pulmonary vascular development.
    Authors: Southwood M, Jeffery TK, Yang X, Upton PD, Hall SM, Atkinson C, Haworth SG, Stewart S, Reynolds PN, Long L, Trembath RC, Morrell NW
    J. Pathol., 2008;214(1):85-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  302. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.
    Authors: Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR
    Nature, 2008;454(7207):1000-4.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  303. Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis.
    Authors: Kane R, Godson C, O'Brien C
    Mol. Vis., 2008;14(0):1138-48.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Binding Assay
  304. Targeting of bone morphogenetic protein growth factor complexes to fibrillin.
    Authors: Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, Bachinger HP, Sakai LY
    J. Biol. Chem., 2008;283(20):13874-88.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Binding Assay
  305. Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage.
    Authors: Elkabetz Y, Panagiotakos G, Al Shamy G, Socci ND, Tabar V, Studer L
    Genes Dev., 2008;22(2):152-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  306. BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling.
    Authors: Jeanpierre S, Nicolini FE, Kaniewski B, Dumontet C, Rimokh R, Puisieux A, Maguer-Satta V
    Blood, 2008;112(8):3154-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  307. Cross-talk between fibroblast growth factor and bone morphogenetic proteins regulates gap junction-mediated intercellular communication in lens cells.
    Authors: Boswell BA, Lein PJ, Musil LS
    Mol. Biol. Cell, 2008;19(6):2631-41.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: Bioassay
  308. Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus.
    Authors: Anderson BC, Christiansen SP, McLoon LK
    Invest. Ophthalmol. Vis. Sci., 2008;49(1):221-9.
    Species: Rabbit
    Sample Types: In Vivo
    Applications: In Vivo
  309. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
    Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM
    Nature, 2008;453(7194):524-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  310. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
    Authors: Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
    Cell Stem Cell, 2008;2(6):602-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  311. High-density lipoproteins affect endothelial BMP-signaling by modulating expression of the activin-like kinase receptor 1 and 2.
    Authors: Yao Y, Shao ES, Jumabay M, Shahbazian A, Ji S, Bostrom KI
    Arterioscler. Thromb. Vasc. Biol., 2008;28(12):2266-74.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  312. Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.
    Authors: Saeki K, Yogiashi Y, Nakahara M, Nakamura N, Matsuyama S, Koyanagi A, Yagita H, Koyanagi M, Kondo Y, Yuo A
    J. Cell. Physiol., 2008;217(1):261-80.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Combinatorial signals of activin/nodal and bone morphogenic protein regulate the early lineage segregation of human embryonic stem cells.
    Authors: Wu Z, Zhang W, Chen G, Cheng L, Liao J, Jia N, Gao Y, Dai H, Yuan J, Cheng L, Xiao L
    J. Biol. Chem., 2008;283(36):24991-5002.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture.
    Authors: Sun Y, Pollard S, Conti L, Toselli M, Biella G, Parkin G, Willatt L, Falk A, Cattaneo E, Smith A
    Mol. Cell. Neurosci., 2008;38(2):245-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  315. Essential role of BMPs in FGF-induced secondary lens fiber differentiation.
    Authors: Boswell BA, Overbeek PA, Musil LS
    Dev. Biol., 2008;324(2):202-12.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  316. Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins.
    Authors: Chen G, Ye Z, Yu X, Zou J, Mali P, Brodsky RA, Cheng L
    Cell Stem Cell, 2008;2(4):345-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  317. Activation of the BMP canonical signaling pathway in human optic nerve head tissue and isolated optic nerve head astrocytes and lamina cribrosa cells.
    Authors: Zode GS, Clark AF, Wordinger RJ
    Invest. Ophthalmol. Vis. Sci., 2007;48(11):5058-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  318. Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway.
    Authors: Knobloch J, Shaughnessy JD, Ruther U
    FASEB J., 2007;21(7):1410-21.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  319. New cell lines from mouse epiblast share defining features with human embryonic stem cells.
    Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD
    Nature, 2007;448(7150):196-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells.
    Authors: Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H
    Blood, 2007;111(4):1933-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  321. Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor.
    Authors: Stabile H, Mitola S, Moroni E, Belleri M, Nicoli S, Coltrini D, Peri F, Pessi A, Orsatti L, Talamo F, Castronovo V, Waltregny D, Cotelli F, Ribatti D, Presta M
    Blood, 2007;109(5):1834-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  322. Predicting evolutionary patterns of mammalian teeth from development.
    Authors: Kavanagh KD, Evans AR, Jernvall J
    Nature, 2007;449(7161):427-32.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  323. Bone morphogenetic proteins promote gliosis in demyelinating spinal cord lesions.
    Authors: Fuller ML, DeChant AK, Rothstein B, Caprariello A, Wang R, Hall AK, Miller RH
    Ann. Neurol., 2007;62(3):288-300.
  324. A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification.
    Authors: Stavridis MP, Lunn JS, Collins BJ, Storey KG
    Development, 2007;134(16):2889-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  325. Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
    Authors: Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S
    Cell, 2007;131(5):861-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  326. A rapid and sensitive bioassay to measure bone morphogenetic protein activity.
    Authors: Zilberberg L, ten Dijke P, Sakai L, Rifkin D
    BMC Cell Biol, 2007;8(0):41.
    Applications: Bioassay
  327. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.
    Authors: Rajesh&lt;/LastName&gt;&lt;ForeNam D&lt;/Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF
    Stem Cells, 2007;25(2):490-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  328. Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.
    Authors: Lin L, Valore EV, Nemeth E, Goodnough JB, Gabayan V, Ganz T
    Blood, 2007;110(6):2182-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  329. Growth differentiation factor-9 has divergent effects on proliferation and steroidogenesis of bovine granulosa cells.
    Authors: Spicer LJ, Aad PY, Allen D, Mazerbourg S, Hsueh AJ
    J. Endocrinol., 2006;189(2):329-39.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  330. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.
    Authors: Lindsley RC, Gill JG, Kyba M, Murphy TL, Murphy KM
    Development, 2006;133(19):3787-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  331. Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct.
    Authors: Maeshima A, Vaughn DA, Choi Y, Nigam SK
    Dev. Biol., 2006;295(2):473-85.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Bioassay
  332. Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis.
    Authors: Ikeya M, Kawada M, Kiyonari H, Sasai N, Nakao K, Furuta Y, Sasai Y
    Development, 2006;133(22):4463-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  333. Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells.
    Authors: Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, Izawa K, Dong Y, Hashiguchi T, Soda Y, Maeda T, Suehiro Y, Tanioka Y, Nakazaki Y, Tani K
    Stem Cells, 2006;24(9):2014-22.
    Species: Primate - Callitrix jacchus (Common Marmoset)
    Sample Types: Whole Cells
    Applications: Bioassay
  334. Multipotent adult progenitor cells from swine bone marrow.
    Authors: Zeng L, Rahrmann E, Hu Q, Lund T, Sandquist L, Felten M, O'Brien TD, O'Brien TD, Zhang J, Verfaillie C
    Stem Cells, 2006;24(11):2355-66.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  335. BMPs restrict the position of premuscle masses in the limb buds by influencing Tcf4 expression.
    Authors: Bonafede A, Kohler T, Rodriguez-Niedenfuhr M, Brand-Saberi B
    Dev. Biol., 2006;299(2):330-44.
    Species: Chicken
    Sample Types: In Ovo
    Applications: In Ovo
  336. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.
    Authors: Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S
    Proc. Natl. Acad. Sci. U.S.A., 2006;103(18):6907-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  337. Inhibitory Smad transcription factors protect arterial endothelial cells from apoptosis induced by BMP4.
    Authors: Kiyono M, Shibuya M
    Oncogene, 2006;25(54):7131-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  338. Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field.
    Authors: Reversade B, De Robertis EM
    Cell, 2005;123(6):1147-60.
    Species: Xenopus
    Sample Types: In Vivo
    Applications: In Vivo
  339. Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer.
    Authors: Ng RK, Gurdon JB
    Proc. Natl. Acad. Sci. U.S.A., 2005;102(6):1957-62.
    Species: Xenopus
    Sample Types: Whole Cells
    Applications: Bioassay
  340. Requirements for endoderm and BMP signaling in sensory neurogenesis in zebrafish.
    Authors: Holzschuh J, Wada N, Wada C, Schaffer A, Javidan Y, Tallafuss A, Bally-Cuif L, Schilling TF
    Development, 2005;132(16):3731-42.
    Species: Xenopus
    Sample Types: In Vivo
    Applications: In Vivo
  341. Retinoic acid signalling specifies intermediate character in the developing telencephalon.
    Authors: Marklund M, Sjodal M, Beehler BC, Jessell TM, Edlund T, Gunhaga L
    Development, 2004;131(17):4323-32.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: Bioassay
  342. hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.
    Authors: Oren A, Toporik A, Biton S, Almogy N, Eshel D, Bernstein J, Savitsky K, Rotman G
    Gene, 2004;331(0):17-31.
    Species: Human
    Sample Types:
    Applications: Bioassay
  343. Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins.
    Authors: Binnerts ME, Wen X, Cante-Barrett K, Bright J, Chen HT, Asundi V, Sattari P, Tang T, Boyle B, Funk W, Rupp F
    Biochem. Biophys. Res. Commun., 2004;315(2):272-80.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  344. Cutting edge: bone morphogenetic protein antagonists Drm/Gremlin and Dan interact with Slits and act as negative regulators of monocyte chemotaxis.
    Authors: Blair DG, Plisov S, Vasiliev G, Perantoni AO, Athanasiou M, Wu JY, Oppenheim JJ
    J. Immunol., 2004;173(10):5914-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  345. Molecular basis of bone morphogenetic protein-4 inhibitory action on progesterone secretion by ovine granulosa cells.
    Authors: Pierre A, Pisselet C, Dupont J, Mandon-Pepin B, Monniaux D, Monget P, Fabre S
    J. Mol. Endocrinol., 2004;33(3):805-17.
    Species: Ovine
    Sample Types: Whole Cells
    Applications: Bioassay
  346. Blocked MAP kinase activity selectively enhances neurotrophic growth responses.
    Authors: Althini S, Usoskin D, Kylberg A, Kaplan PL, Ebendal T
    Mol. Cell. Neurosci., 2004;25(2):345-54.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  347. Multiple roles of Sox2, an HMG-box transcription factor in avian neural crest development.
    Authors: Wakamatsu Y, Endo Y, Osumi N, Weston JA
    Dev. Dyn., 2004;229(1):74-86.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  348. BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation.
    Authors: Moser M, Binder O, Wu Y, Aitsebaomo J, Ren R, Bode C, Bautch VL, Conlon FL, Patterson C
    Mol. Cell. Biol., 2003;23(16):5664-79.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  349. Effect of recombinant human bone morphogenetic protein-4 with carriers in rat calvarial defects.
    Authors: Ahn SH, Kim CS, Suk HJ, Lee YJ, Choi SH, Chai JK, Kim CK, Han SB, Cho KS
    J. Periodontol., 2003;74(6):787-97.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  350. Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2.
    Authors: Viti J, Gulacsi A, Lillien L
    J. Neurosci., 2003;23(13):5919-27.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  351. FGF8 acts as a right determinant during establishment of the left-right axis in the rabbit.
    Authors: Fischer A, Viebahn C, Blum M
    Curr. Biol., 2002;12(21):1807-16.
    Species: Rabbit
    Sample Types: Whole Cells
    Applications: Bioassay
  352. Prkci is required for a non-autonomous signal that coordinates cell polarity during cavitation.
    Authors: In Kyoung Mah, Mah I, Soloff R, Izuhara A, Lakeland D, Mariani F
    Dev Biol, 0;416(1):82-97.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. Can Recombinant Human BMP-4 Protein (Catalog # 314-BP or 314-BP/CF) be reconstituted in PBS or water?

    • Recombinant Human BMP-4 (Catalog # 314-BP or 314-BP/CF) needs to be reconstituted to 50-200 μg/mL in sterile 4 mM HCl containing 0.1% BSA, or 4 mM HCl to ensure optimal recovery, stability, and activity. This protein is hydrophobic by nature, so it requires an acidic buffer for reconstitution to go completely into solution. Stability testing has been evaluated on the protein with these reconstitution conditions; we can guarantee performance under these reconstitution conditions. When the protein is diluted with the cell culture media or buffers to the working concentration, the concentration of the acid should be buffered or negligible.

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