Recombinant Human BMP-4 Protein

  (270 citations)
(3 Reviews)
    
Datasheet / CoA / SDS
Product Details
Citations (270)
FAQs
Reviews
  • Purity
    >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Endotoxin Level
    <0.01 EU per 1 μg of the protein by the LAL method.
  • Activity
    Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Binnerts, M.E. et al. (2004) Biochem. Biophys. Res. Commun. 315(2):272. The ED50 for this effect is typically 2.5-15 ng/mL.
  • Source
    Mouse myeloma cell line, NS0-derived human BMP-4 protein
    Ser293-Arg408
  • Accession #
  • N-terminal Sequence
    Analysis
    Ser293
  • Structure / Form
    Disulfide-linked homodimer
  • Predicted Molecular Mass
    13 kDa (monomer)
  • SDS-PAGE
    22-25 kDa, reducing conditions
    37-41 kDa, non-reducing conditions
Product Datasheets

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Carrier Free
What does CF mean?
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
What formulation is right for me?
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
314-BP
 
314-BP/CF
Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
 
Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Reconstitution Reconstitute at 50-200 μg/mL in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.
 
Reconstitution Reconstitute at 50-200 μg/mL in sterile 4 mM HCl.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
 
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
 
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Data Images
Recombinant Human BMP-4 (Catalog #
314-BP/CF) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line. The ED50 for this effect is 2.5-15 ng/mL.
1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.

 

Background: BMP-4

BMP-4 is a TGF-beta superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair (1-5). The human BMP-4 precursor contains a 273 amino acid (aa) propeptide and a 116 aa mature protein (6). Processing of the propeptide by furin or proprotein convertase 6 enables the formation of the mature disulfide-linked homodimeric BMP-4 and facilitates its secretion. Similar intracellular processes may lead to the formation and recreation of BMP4/BMP7
disulfide-linked heterodimer (7-9). Mature human and mouse BMP-4 share 98% aa sequence identity. Human BMP-4 shares 85% aa sequence identity with human BMP-2 and less than 50% with other human BMPs. Compared to BMP-4 homodimers, BMP-4/BMP-7 heterodimers exhibit a greater potency in inducing osteogenic differentiation (9). In Xenopus, the heterodimers can also induce the formation of mesoderm, whereas BMP-4 homodimers only provide ventralizing signals for existing mesoderm (10). BMP-4 signals through tetrameric complexes composed of type I (primarily Activin RIA or BMPR-IA) and type II (primarily Activin RIIA or BMPR-II) receptors (11, 12). The bioavailability of BMP-4 is regulated by its interaction with multiple proteins and glycosaminoglycans (13-15).

 

  • References:
    1. Zhang, P. et al. (2008) Blood 111:1933.
    2. Gambaro, K. et al. (2006) Cell Death Differ. 13:1075.
    3. Simic, P. and S. Vukicevic (2005) Cytokine Growth Factor Rev. 16:299.
    4. Sadlon, T.J. et al. (2004) Stem Cells 22:457.
    5. Frank, D.B. et al. (2005) Circ. Res. 97:496.
    6. Wozney, J. et al. (1988) Science 242:1528.
    7. Cui, Y. et al. (1998) EMBO J. 17:4735.
    8. Cui, Y. et al. (2001) Genes Dev. 15:2797.
    9. Aono, A. et al. (1995) Biochem. Biophys. Res. Commun. 210:670.
    10. Nishimatsu, S. and G.H. Thomsen (1998) Mech. Dev. 74:75.
    11. Chen, D. et al. (2004) Growth Factors 22:233.
    12. Lavery, K. et al. (2008) J. Biol. Chem. April 24 epub.
    13. Rosen, V. (2006) Ann. N.Y. Acad. Sci. 1068:19.
    14. Jones, C.M. and J.C. Smith (1998) Dev. Biol. 194:12.
    15. Takada, T. et al. (2003) J. Biol. Chem. 278:43229.
  • Long Name:
    Bone Morphogenetic Protein 4
  • Entrez Gene IDs:
    652 (Human); 12159 (Mouse); 25296 (Rat); 30612 (Zebrafish)
  • Alternate Names:
    BMP-2B; BMP2B1; BMP2BMCOPS6; BMP4; BMP-4; Bone morphogenetic protein 2B; bone morphogenetic protein 4; DVR4; OFC11; ZYME
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

270 Citations: Showing 1 - 10
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Species
Applications
Sample Type
  1. An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling
    Authors: H Jun, H Yu, J Gong, J Jiang, X Qiao, E Perkey, DI Kim, MP Emont, AG Zestos, JS Cho, J Liu, RT Kennedy, I Maillard, XZS Xu, J Wu
    Nat. Med., 2018;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  2. Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype
    Authors: F Wang, V Zachar, CP Pennisi, T Fink, Y Maeda, J Emmersen
    Int J Mol Sci, 2018;19(2):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  3. Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing
    Authors: C Long, H Li, M Tiburcy, C Rodriguez-, V Kyrychenko, H Zhou, Y Zhang, YL Min, JM Shelton, PPA Mammen, NY Liaw, WH Zimmermann, R Bassel-Dub, JW Schneider, EN Olson
    Sci Adv, 2018;4(1):eaap9004.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  4. Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
    Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
    Sci Rep, 2018;8(1):1561.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  5. PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation
    Authors: JJ Gell, J Zhao, D Chen, TJ Hunt, AT Clark
    Stem Cell Res, 2018;27(0):46-56.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  6. Human iPS Cell-based Liver-like Tissue Engineering at Extrahepatic Sites in Mice as a New Cell Therapy for Hemophilia B
    Authors: R Okamoto, K Takayama, N Akita, Y Nagamoto, D Hosokawa, S Iizuka, F Sakurai, H Suemizu, K Ohashi, H Mizuguchi
    Cell Transplant, 2018;27(2):299-309.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  7. Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage
    Authors: V Pursani, D Bhartiya, V Tanavde, M Bashir, P Sampath
    Stem Cell Res Ther, 2018;9(1):97.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  8. Enhanced differentiation of human pluripotent stem cells into cardiomyocytes by bacteria-mediated transcription factors delivery
    Authors: Y Jin, Y Liu, Z Li, K Santostefa, J Shi, X Zhang, D Wu, Z Cheng, W Wu, N Terada, S Jin, F Bai
    PLoS ONE, 2018;13(3):e0194895.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  9. Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics
    Authors: NG Kooreman, PE de Almeida, JP Stack, RV Nelakanti, S Diecke, NY Shao, RJ Swijnenbur, V Sanchez-Fr, E Matsa, C Liu, AJ Connolly, JF Hamming, PHA Quax, MA Brehm, DL Greiner, LD Shultz, JC Wu
    Cell Rep, 2017;20(8):1978-1990.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  10. Thrombospondin-1 (TSP-1), a new bone morphogenetic protein-2 and -4 (BMP-2/4) antagonist identified in pituitary cells
    Authors: C Sallon, I Callebaut, I Boulay, J Fontaine, D Logeart-Av, C Henriquet, M Pugnière, X Cayla, P Monget, G Harichaux, V Labas, S Canepa, C Taragnat
    J. Biol. Chem., 2017;0(0):.
    Species: Human
    Sample Type: Recombinant Protein
    Application: Bioassay
  11. Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
    Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
    Cell Stem Cell, 2017;21(2):179-194.e4.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  12. A pluripotent stem cell-based model for post-implantation human amniotic sac development
    Authors: Y Shao, K Taniguchi, RF Townshend, T Miki, DL Gumucio, J Fu
    Nat Commun, 2017;8(1):208.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  13. Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis
    Authors: NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry
    Cell Rep, 2017;20(7):1597-1608.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  14. Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1?
    Authors: KM Tsang, JS Hyun, KT Cheng, M Vargas, D Mehta, M Ushio-Fuka, L Zou, KV Pajcini, J Rehman, AB Malik
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  15. Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells
    Authors: F Hawkins, P Kramer, A Jacob, I Driver, DC Thomas, KB McCauley, N Skvir, AM Crane, AA Kurmann, AN Hollenberg, S Nguyen, BG Wong, AS Khalil, SX Huang, S Guttentag, JR Rock, JM Shannon, BR Davis, DN Kotton
    J. Clin. Invest., 2017;127(6):2277-2294.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  16. Direct comparison of distinct naive pluripotent states in human embryonic stem cells
    Authors: S Warrier, M Van der Je, G Duggal, L Tilleman, E Sutherland, J Taelman, M Popovic, S Lierman, S Chuva De S, A Van Soom, L Peelman, F Van Nieuwe, DIM De Coninck, B Menten, P Mestdagh, J Van de Som, D Deforce, P De Sutter, B Heindryckx
    Nat Commun, 2017;8(0):15055.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  17. Recapitulating and Correcting Marfan Syndrome in a Cellular Model
    Authors: JW Park, L Yan, C Stoddard, X Wang, Z Yue, L Crandall, T Robinson, Y Chang, K Denton, E Li, B Jiang, Z Zhang, K Martins-Ta, SP Yee, H Nie, F Gu, W Si, T Xie, L Yue, RH Xu
    Int. J. Biol. Sci., 2017;13(5):588-603.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  18. Differentiation of cardiomyocytes and generation of human engineered heart tissue
    Authors: K Breckwoldt, D Letuffe-Br, I Mannhardt, T Schulze, B Ulmer, T Werner, A Benzin, B Klampe, MC Reinsch, S Laufer, A Shibamiya, M Prondzynsk, G Mearini, D Schade, S Fuchs, C Neuber, E Krämer, U Saleem, ML Schulze, ML Rodriguez, T Eschenhage, A Hansen
    Nat Protoc, 2017;12(6):1177-1197.
    Species: Human
    Sample Type: Whole Tissue
    Application: Bioassay
  19. Bone morphogenetic protein signaling mediated by ALK-2 and DLX2 regulates apoptosis in glioma-initiating cells
    Authors: E Raja, A Komuro, R Tanabe, S Sakai, Y Ino, N Saito, T Todo, M Morikawa, H Aburatani, D Koinuma, C Iwata, K Miyazono
    Oncogene, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  20. In Vitro Micropatterned Human Pluripotent Stem Cell Test (�P-hPST) for Morphometric-Based Teratogen Screening
    Authors: J Xing, Y Cao, Y Yu, H Li, Z Song, H Yu
    Sci Rep, 2017;7(1):8491.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  21. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling
    Authors: KB McCauley, F Hawkins, M Serra, DC Thomas, A Jacob, DN Kotton
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  22. Supraphysiological levels of GDF11 induce striated muscle atrophy
    Authors: DW Hammers, M Merscham-B, JY Hsiao, S Engst, JJ Hartman, HL Sweeney
    EMBO Mol Med, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  23. Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
    Authors: F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier
    Nat Protoc, 2017;12(4):814-827.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  24. Fetal Therapy Model of Myelomeningocele with Three-Dimensional Skin Using Amniotic Fluid Cell-Derived Induced Pluripotent Stem Cells
    Authors: K Kajiwara, T Tanemoto, S Wada, J Karibe, N Ihara, Y Ikemoto, T Kawasaki, Y Oishi, O Samura, K Okamura, S Takada, H Akutsu, H Sago, A Okamoto, A Umezawa
    Stem Cell Reports, 2017;8(6):1701-1713.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  25. Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency
    Authors: JH Lee, S Laronde, TJ Collins, Z Shapovalov, B Tanasijevi, JD McNicol, A Fiebig-Com, YD Benoit, JB Lee, RR Mitchell, M Bhatia
    Cell Rep, 2017;19(1):20-35.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  26. Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection
    Authors: F Sakurai, S Mitani, T Yamamoto, K Takayama, M Tachibana, K Watashi, T Wakita, S Iijima, Y Tanaka, H Mizuguchi
    Sci Rep, 2017;7(0):45698.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  27. Gelatin device for the delivery of growth factors involved in endochondral ossification
    Authors: LA Ahrens, D Vonwil, J Christense, VP Shastri
    PLoS ONE, 2017;12(4):e0175095.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  28. Physico-electrochemical Characterization of Pluripotent Stem Cells during Self-Renewal or Differentiation by a Multi-modal Monitoring System
    Authors: K Low, LY Wong, M Maldonado, C Manjunath, CB Horner, M Perez, NV Myung, J Nam
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  29. Highly Efficient Differentiation of Endothelial Cells from Pluripotent Stem Cells Requires the MAPK and the PI3K Pathways
    Authors: A Harding, E Cortez-Tol, NL Magner, JR Beegle, DP Coleal-Ber, D Hao, A Wang, JA Nolta, P Zhou
    Stem Cells, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  30. Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
    Authors: AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, A Solovyov, C Husser, M Olszewska, J Teruya-Fel, D Perumal, VM Klimek, A Spyridonid, RK Rampal, L Silverman, EP Reddy, E Papaemmanu, S Parekh, BD Greenbaum, CS Leslie, MG Kharas, EP Papapetrou
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  31. In�Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling
    Authors: K Yamamizu, M Iwasaki, H Takakubo, T Sakamoto, T Ikuno, M Miyoshi, T Kondo, Y Nakao, M Nakagawa, H Inoue, JK Yamashita
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  32. Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity
    Authors: Y Choudhury, YC Toh, J Xing, Y Qu, J Poh, L Huan, HS Tan, R Kanesvaran, H Yu, MH Tan
    Sci Rep, 2017;7(0):41238.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  33. Wnt/?-catenin promotes gastric fundus specification in mice and humans
    Authors: KW McCracken, E Aihara, B Martin, CM Crawford, T Broda, J Treguier, X Zhang, JM Shannon, MH Montrose, JM Wells
    Nature, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  34. Integrated RNA-seq and DNase-seq analyses identify phenotype-specific BMP4 signaling in breast cancer
    Authors: M Ampuja, T Rantapero, A Rodriguez-, M Palmroth, EL Alarmo, M Nykter, A Kallioniem
    BMC Genomics, 2017;18(1):68.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  35. Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-?2 in Human TM Cells
    Authors: AA Mody, RJ Wordinger, AF Clark
    Invest. Ophthalmol. Vis. Sci, 2017;58(2):849-859.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  36. Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using human pluripotent stem cells
    Nat Protoc, 2017;12(1):15-31.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  37. Induction of senescence in primary glioblastoma cells by serum and TGF?
    Authors: R Kumar, A Gont, TJ Perkins, JEL Hanson, IAJ Lorimer
    Sci Rep, 2017;7(1):2156.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  38. BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-? receptor type I ALK5
    Authors: LK Bollum, K Huse, MP Oksvold, B Bai, VI Hilden, L Forfang, SO Yoon, S Wälchli, EB Smeland, JH Myklebust
    PLoS ONE, 2017;12(5):e0177188.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  39. Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate
    Authors: AG Freire, A Waghray, F Soares-da-, TP Resende, DF Lee, CF Pereira, DS Nascimento, IR Lemischka, P Pinto-do-Ó
    Stem Cell Reports, 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  40. GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency
    Authors: C Krendl, D Shaposhnik, V Rishko, C Ori, C Ziegenhain, S Sass, L Simon, NS Müller, T Straub, KE Brooks, SL Chavez, W Enard, FJ Theis, M Drukker
    Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  41. Pericyte-derived Bone Morphogenetic Protein 4 Underlies White Matter Damage after Chronic Hypoperfusion
    Authors: MT Uemura, M Ihara, T Maki, T Nakagomi, S Kaji, K Uemura, T Matsuyama, RN Kalaria, A Kinoshita, R Takahashi
    Brain Pathol., 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  42. Human iPSC-derived myocardium-on-chip with capillary-like flow for personalized medicine
    Authors: BW Ellis, A Acun, UI Can, P Zorlutuna
    Biomicrofluidics, 2017;11(2):024105.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  43. Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells
    Authors: Y Tachida, N Izumi, T Sakurai, H Kobayashi
    Biol Open, 2017;6(3):370-380.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  44. Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols
    Authors: D Jeziorowsk, V Fontaine, C Jouve, E Villard, S Dussaud, D Akbar, V Letang, P Cervello, JM Itier, MP Pruniaux, JS Hulot
    Int J Mol Sci, 2017;18(6):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  45. Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells
    Authors: E Giacomelli, M Bellin, L Sala, BJ van Meer, LG Tertoolen, VV Orlova, CL Mummery
    Development, 2017;144(6):1008-1017.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  46. Serum Proteases Potentiate BMP-Induced Cell Cycle Re-entry of Dedifferentiating Muscle Cells during Newt Limb Regeneration
    Authors: I Wagner, H Wang, PM Weissert, WL Straube, A Shevchenko, M Gentzel, G Brito, A Tazaki, C Oliveira, T Sugiura, A Shevchenko, A Simon, DN Drechsel, EM Tanaka
    Dev. Cell, 2017;40(6):608-617.e6.
    Application: WB Standard
  47. Efficient production of trophoblast lineage cells from human induced pluripotent stem cells
    Authors: J Kojima, A Fukuda, H Taira, T Kawasaki, H Ito, N Kuji, K Isaka, A Umezawa, H Akutsu
    Lab. Invest, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  48. Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract
    Authors: BA Boswell, A Korol, JA West-Mays, LS Musil
    Mol. Biol. Cell, 2017;0(0):.
    Species: Chicken
    Sample Type: Whole Cells
    Application: Bioassay
  49. Development of a human cardiac organoid injury model reveals innate regenerative potential
    Authors: HK Voges, RJ Mills, DA Elliott, RG Parton, ER Porrello, JE Hudson
    Development, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  50. Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair
    Authors: M Tiburcy, JE Hudson, P Balfanz, S Schlick, T Meyer, ML Chang Liao, E Levent, F Raad, S Zeidler, E Wingender, J Riegler, M Wang, JD Gold, I Kehat, E Wettwer, U Ravens, P Dierickx, LW van Laake, MJ Goumans, S Khadjeh, K Toischer, G Hasenfuss, LA Couture, A Unger, WA Linke, T Araki, B Neel, G Keller, L Gepstein, JC Wu, WH Zimmermann
    Circulation, 2017;135(19):1832-1847.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  51. Bone morphogenetic protein-7 (BMP-7) augments insulin sensitivity in mice with type II diabetes mellitus by potentiating PI3K/AKT pathway
    Authors: T Chattopadh, RR Singh, S Gupta, A Surolia
    Biofactors, 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  52. Nutritional modulation of mouse and human liver bud growth through a branched-amino acid metabolism
    Authors: H Koike, RR Zhang, Y Ueno, K Sekine, YW Zheng, T Takebe, H Taniguchi
    Development, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  53. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells
    Authors: A Taguchi, R Nishinakam
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  54. Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes
    Authors: G Yücel, Z Zhao, I El-Battraw, H Lan, S Lang, X Li, F Buljubasic, WH Zimmermann, L Cyganek, J Utikal, U Ravens, T Wieland, M Borggrefe, XB Zhou, I Akin
    Sci Rep, 2017;7(1):2935.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  55. Rapid DNA replication origin licensing protects stem cell pluripotency
    Authors: JP Matson, R Dumitru, P Coryell, RM Baxley, W Chen, K Twaroski, BR Webber, J Tolar, AK Bielinsky, JE Purvis, JG Cook
    Elife, 2017;6(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  56. Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium
    Authors: J Li, I Minami, M Shiozaki, L Yu, S Yajima, S Miyagawa, Y Shiba, N Morone, S Fukushima, M Yoshioka, S Li, J Qiao, X Li, L Wang, H Kotera, N Nakatsuji, Y Sawa, Y Chen, L Liu
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  57. Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium
    Authors: N Yucer, M Holzapfel, T Jenkins Vo, L Lenaeus, L Ornelas, A Laury, D Sareen, R Barrett, BY Karlan, CN Svendsen
    Sci Rep, 2017;7(1):10741.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  58. Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2
    Authors: P Scerbo, L Marchal, L Kodjabachi
    Elife, 2017;6(0):.
    Species: Xenopus
    Sample Type: In Vivo
    Application: In Vivo
  59. Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence
    Authors: N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra
    Nat Commun, 2017;8(0):15380.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  60. In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells
    Authors: D Jung, J Xiong, M Ye, X Qin, L Li, S Cheng, M Luo, J Peng, J Dong, F Tang, W Shen, MM Matzuk, K Kee
    Nat Commun, 2017;8(0):15680.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  61. Induced pluripotent stem cell-derived limbal epithelial cells (LiPSC) as a cellular alternative for in vitro ocular toxicity testing
    Authors: E Aberdam, I Petit, L Sangari, D Aberdam
    PLoS ONE, 2017;12(6):e0179913.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  62. Expression of the Human Herpesvirus 6A Latency-Associated Transcript U94A Disrupts Human Oligodendrocyte Progenitor Migration
    Authors: A Campbell, JM Hogestyn, CJ Folts, B Lopez, C Pröschel, D Mock, M Mayer-Prös
    Sci Rep, 2017;7(1):3978.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  63. MxA Is a Novel Regulator of Endosome-Associated Transcriptional Signaling by Bone Morphogenetic Proteins 4 and 9 (BMP4 and BMP9)
    PLoS ONE, 2016;11(11):e0166382.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  64. Yes-Associated Protein Inhibits Transcription of Myocardin and Attenuates Differentiation of Vascular Smooth Muscle Cell from Cardiovascular Progenitor Cell Lineage
    Stem Cells, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  65. Improved hematopoietic differentiation of human pluripotent stem cells via estrogen receptor signaling pathway
    Cell Biosci, 2016;6(1):50.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  66. Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes
    Stem Cells Transl Med, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  67. A new hERG allosteric modulator rescues genetic and drug-induced long-QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells
    EMBO Mol Med, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  68. A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients
    Elife, 2016;5(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  69. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes
    Stem Cell Reports, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  70. Medial HOXA genes demarcate haematopoietic stem cell fate during human development
    Nat Cell Biol, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  71. Microfabric Vessels for Embryoid Body Formation and Rapid Differentiation of Pluripotent Stem Cells
    Sci Rep, 2016;6(0):31063.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  72. Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease
    Authors: Mariko Horii
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  73. Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves
    EBioMedicine, 2016;10(0):282-90.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  74. Bovine ovarian stem cells differentiate into germ cells and oocyte-like structures after culture in vitro
    Authors: G B de Souza
    Reprod. Domest. Anim, 2016;0(0):.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  75. Five colour variants of bright luminescent protein for real-time multicolour bioimaging
    Nat Commun, 2016;7(0):13718.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  76. Tumor-Derived Factors and Reduced p53 Promote Endothelial Cell Centrosome Over-Duplication
    PLoS ONE, 2016;11(12):e0168334.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  77. Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker
    Nat. Biotechnol, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  78. Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells
    Nat Commun, 2016;7(0):13602.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  79. Automated image analysis with the potential for process quality control applications in stem cell maintenance and differentiation
    Authors: Robert Thomas
    Biotechnol. Prog., 2016;32(1):215-23.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  80. Coupling switch of P2Y-IP3 receptors mediates differential Ca(2+) signaling in human embryonic stem cells and derived cardiovascular progenitor cells
    Authors: Huang-Tian Yang
    Purinergic Signal., 2016;12(3):465-78.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  81. In�Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts
    Authors: S Kadota, L Pabon, H Reinecke, CE Murry
    Stem Cell Reports, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  82. The Binding of the Bone Morphogenetic Protein Antagonist Gremlin to Kidney Heparan Sulfate: Such Binding is not Essential for BMP Antagonism
    Authors: Arnold Junior Tatsinkam
    Int. J. Biochem. Cell Biol, 2016;0(0):.
    Application: Bioassay
  83. Comparison between pediatric and adult adipose mesenchymal stromal cells
    Authors: Olivier Abbo
    Cytotherapy, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  84. Calreticulin is a secreted BMP antagonist, expressed in Hensen's node during neural induction
    Authors: Irene De Almeida
    Dev. Biol, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  85. The involvement of protein kinase C-? in isoflurane induced preconditioning of human embryonic stem cell--derived Nkx2.5(+) cardiac progenitor cells
    Authors: IA Song, AY Oh, JH Kim, YM Choi, YT Jeon, JH Ryu, JW Hwang
    BMC Anesthesiol, 2016;16(0):13.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  86. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
    Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
    Nat. Med., 2016;22(12):1421-1427.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  87. Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer.
    Authors: Hermanson D, Bendzick L, Pribyl L, McCullar V, Vogel R, Miller J, Geller M, Kaufman D
    Stem Cells, 2016;34(1):93-101.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  88. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling
    Stem Cell Res Ther, 2016;7(1):115.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  89. ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation
    Stem Cell Res, 2016;17(2):222-227.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  90. The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells.
    Authors: Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D'Souza S, Snoeck H
    Nat Protoc, 2015;10(3):413-25.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  91. Bone morphogenetic proteins are mediators of luteolysis in the human corpus luteum.
    Authors: Nio-Kobayashi J, Trendell J, Giakoumelou S, Boswell L, Nicol L, Kudo M, Sakuragi N, Iwanaga T, Duncan W
    Endocrinology, 2015;156(4):1494-503.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  92. Generation of articular chondrocytes from human pluripotent stem cells.
    Authors: Craft A, Rockel J, Nartiss Y, Kandel R, Alman B, Keller G
    Nat Biotechnol, 2015;33(6):638-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  93. Constitutive activation of myosin-dependent contractility sensitizes glioma tumor-initiating cells to mechanical inputs and reduces tissue invasion.
    Authors: Wong S, Ulrich T, Deleyrolle L, MacKay J, Lin J, Martuscello R, Jundi M, Reynolds B, Kumar S
    Cancer Res, 2015;75(6):1113-22.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  94. Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.
    Authors: Gori J, Butler J, Chan Y, Chandrasekaran D, Poulos M, Ginsberg M, Nolan D, Elemento O, Wood B, Adair J, Rafii S, Kiem H
    J Clin Invest, 2015;125(3):1243-54.
    Species: Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
    Sample Type: Whole Cells
    Application: Bioassay
  95. Alternative Routes to Induce Naive Pluripotency in Human Embryonic Stem Cells.
    Authors: Duggal G, Warrier S, Ghimire S, Broekaert D, Van der Jeught M, Lierman S, Deroo T, Peelman L, Van Soom A, Cornelissen R, Menten B, Mestdagh P, Vandesompele J, Roost M, Slieker R, Heijmans B, Deforce D, De Sutter P, de Sousa Lopes S, Heindryckx B
    Stem Cells, 2015;33(9):2686-98.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  96. Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells.
    Authors: Lee J, Graham M, Collins T, Lee J, Hong S, McNicol A, Shapovalova Z, Bhatia M
    Stem Cells, 2015;33(4):1142-52.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  97. Improved hematopoietic differentiation efficiency of gene-corrected beta-thalassemia induced pluripotent stem cells by CRISPR/Cas9 system.
    Authors: Song B, Fan Y, He W, Zhu D, Niu X, Wang D, Ou Z, Luo M, Sun X
    Stem Cells Dev, 2015;24(9):1053-65.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  98. Increased culture density is linked to decelerated proliferation, prolonged G1 phase, and enhanced propensity for differentiation of self-renewing human pluripotent stem cells.
    Authors: Wu J, Fan Y, Tzanakakis E
    Stem Cells Dev, 2015;24(7):892-903.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  99. Cytoskeletal Reorganization Drives Mesenchymal Condensation and Regulates Downstream Molecular Signaling.
    Authors: Ray P, Chapman S
    PLoS ONE, 2015;10(8):e0134702.
    Species: Chicken
    Sample Type: Whole Tissue
    Application: Bioassay
  100. GSK3beta inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells.
    Authors: Kitajima K, Nakajima M, Kanokoda M, Kyba M, Dandapat A, Tolar J, Saito M, Toyoda M, Umezawa A, Hara T
    Exp Hematol, 2015;44(1):68-74.e10.
  101. Transcription factor binding dynamics during human ES cell differentiation.
    Authors: Tsankov, Alexande, Gu, Hongcang, Akopian, Veronika, Ziller, Michael, Donaghey, Julie, Amit, Ido, Gnirke, Andreas, Meissner, Alexande
    Nature, 2015;518(7539):344-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  102. Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile.
    Authors: Sugawa F, Arauzo-Bravo M, Yoon J, Kim K, Aramaki S, Wu G, Stehling M, Psathaki O, Hubner K, Scholer H
    EMBO J, 2015;34(8):1009-24.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  103. BMP4 depletion by miR-200 inhibits tumorigenesis and metastasis of lung adenocarcinoma cells.
    Authors: Kim J, Kurie J, Ahn Y
    Mol Cancer, 2015;14(1):173.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  104. Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells.
    Authors: Wong, Amy P, Chin, Stephani, Xia, Sunny, Garner, Jodi, Bear, Christin, Rossant, Janet
    Nat Protoc, 2015;10(3):363-81.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  105. Heightened potency of human pluripotent stem cell lines created by transient BMP4 exposure.
    Authors: Yang Y, Adachi K, Sheridan M, Alexenko A, Schust D, Schulz L, Ezashi T, Roberts R
    Proc Natl Acad Sci U S A, 2015;112(18):E2337-46.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  106. Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis.
    Authors: Kim M, Horst A, Blinka S, Stamm K, Mahnke D, Schuman J, Gundry R, Tomita-Mitchell A, Lough J
    PLoS ONE, 2015;10(2):e0118670.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  107. Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells.
    Authors: Iyer D, Gambardella L, Bernard W, Serrano F, Mascetti V, Pedersen R, Talasila A, Sinha S
    Development, 2015;142(8):1528-41.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  108. Transcriptional profiling of ectoderm specification to keratinocyte fate in human embryonic stem cells.
    Authors: Tadeu A, Lin S, Hou L, Chung L, Zhong M, Zhao H, Horsley V
    PLoS ONE, 2015;10(4):e0122493.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  109. A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face.
    Authors: Hu D, Young N, Li X, Xu Y, Hallgrimsson B, Marcucio R
    Development, 2015;142(3):567-74.
    Species: Chicken
    Sample Type: Whole Organism
    Application: In Vivo
  110. Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1.
    Authors: Majumder A, Syed K, Joseph S, Scambler P, Dutta D
    J Biol Chem, 2015;290(21):13053-63.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  111. Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes.
    Authors: Maury Y, Come J, Piskorowski R, Salah-Mohellibi N, Chevaleyre V, Peschanski M, Martinat C, Nedelec S
    Nat Biotechnol, 2015;33(1):89-96.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  112. Oligodendroglial maturation is dependent on intracellular protein shuttling.
    Authors: Gottle P, Sabo J, Heinen A, Venables G, Torres K, Tzekova N, Parras C, Kremer D, Hartung H, Cate H, Kury P
    J Neurosci, 2015;35(3):906-19.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  113. A BMP7 Variant Inhibits Tumor Angiogenesis In Vitro and In Vivo through Direct Modulation of Endothelial Cell Biology.
    Authors: Tate C, Mc Entire J, Pallini R, Vakana E, Wyss L, Blosser W, Ricci-Vitiani L, D'Alessandris Q, Morgante L, Giannetti S, Larocca L, Todaro M, Benfante A, Colorito M, Stassi G, De Maria R, Rowlinson S, Stancato L
    PLoS ONE, 2015;10(4):e0125697.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  114. Additive Effects of Retinoic Acid (RA) and Bone Morphogenetic Protein 4 (BMP-4) Apoptosis Signaling in Retinoblastoma Cell Lines.
    Authors: Muller P, Doliva R, Busch M, Philippeit C, Stephan H, Dunker N
    PLoS ONE, 2015;10(7):e0131467.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  115. Enhanced Electrical Integration of Engineered Human Myocardium via Intramyocardial versus Epicardial Delivery in Infarcted Rat Hearts.
    Authors: Gerbin K, Yang X, Murry C, Coulombe K
    PLoS ONE, 2015;10(7):e0131446.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  116. Role of bone morphogenetic protein 4 in the differentiation of brown fat-like adipocytes.
    Authors: Xue, Ruidan, Wan, Yun, Zhang, Shuo, Zhang, Qiongyue, Ye, Hongying, Li, Yiming
    Am J Physiol Endocrinol Metab, 2014;306(4):E363-72.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  117. Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression.
    Authors: Laperrousaz B, Jeanpierre S, Sagorny K, Voeltzel T, Ramas S, Kaniewski B, Ffrench M, Salesse S, Nicolini F, Maguer-Satta V
    Blood, 2014;122(23):3767-77.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  118. Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin.
    Authors: Olsen O, Wader K, Misund K, Vatsveen T, Ro T, Mylin A, Turesson I, Stordal B, Moen S, Standal T, Waage A, Sundan A, Holien T
    Blood Cancer J, 2014;4(0):e196.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  119. Real-time discrimination between proliferation and neuronal and astroglial differentiation of human neural stem cells.
    Authors: Lee, Rimi, Kim, Il-Sun, Han, Nalae, Yun, Seokhwan, Park, Kook In, Yoo, Kyung-Hw
    Sci Rep, 2014;4(0):6319.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  120. Inner ear hair cell-like cells from human embryonic stem cells.
    Authors: Ronaghi, Mohammad, Nasr, Marjan, Ealy, Megan, Durruthy-Durruthy, Robert, Waldhaus, Joerg, Diaz, Giovanni, Joubert, Lydia-Ma, Oshima, Kazuo, Heller, Stefan
    Stem Cells Dev, 2014;23(11):1275-84.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  121. High efficient differentiation of functional hepatocytes from porcine induced pluripotent stem cells.
    Authors: Ao, Ying, Mich-Basso, Jocelyn, Lin, Bo, Yang, Lei
    PLoS ONE, 2014;9(6):e100417.
    Species: Porcine
    Sample Type: Whole Cells
    Application: Bioassay
  122. BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity.
    Authors: Cao Y, Slaney C, Bidwell B, Parker B, Johnstone C, Rautela J, Eckhardt B, Anderson R
    Cancer Res, 2014;74(18):5091-102.
  123. Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies.
    Authors: Dominguez, Antonia, Chiang, H Rosari, Sukhwani, Meena, Orwig, Kyle E, Reijo Pera, Renee A
    Sci Rep, 2014;4(0):6432.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  124. Ligand- and stage-dependent divergent functions of BMP signaling in the differentiation of embryonic skeletogenic progenitors in vitro.
    Authors: Lorda-Diez C, Montero J, Choe S, Garcia-Porrero J, Hurle J
    J Bone Miner Res, 2014;29(3):735-48.
    Species: Chicken
    Sample Type: Whole Cells
    Application: Bioassay
  125. Directed differentiation of patient-specific induced pluripotent stem cells identifies the transcriptional repression and epigenetic modification of NKX2-5, HAND1, and NOTCH1 in hypoplastic left heart syndrome.
    Authors: Kobayashi, Junko, Yoshida, Masashi, Tarui, Suguru, Hirata, Masataka, Nagai, Yusuke, Kasahara, Shingo, Naruse, Keiji, Ito, Hiroshi, Sano, Shunji, Oh, Hidemasa
    PLoS ONE, 2014;9(7):e102796.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  126. Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium.
    Authors: Turnbull I, Karakikes I, Serrao G, Backeris P, Lee J, Xie C, Senyei G, Gordon R, Li R, Akar F, Hajjar R, Hulot J, Costa K
    FASEB J, 2014;28(2):644-54.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  127. Efficient generation of lung and airway epithelial cells from human pluripotent stem cells.
    Authors: Huang, Sarah X, Islam, Mohammad, O'Neill, John, Hu, Zheng, Yang, Yong-Gua, Chen, Ya-Wen, Mumau, Melanie, Green, Michael, Vunjak-Novakovic, Gordana, Bhattacharya, Jahar, Snoeck, Hans-Wil
    Nat Biotechnol, 2014;32(1):84-91.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  128. Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers.
    Authors: Lam A, Freedman B, Morizane R, Lerou P, Valerius M, Bonventre J
    J Am Soc Nephrol, 2014;25(6):1211-25.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  129. Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling.
    Authors: Jakobsen R, Ostrup E, Zhang X, Mikkelsen T, Brinchmann J
    PLoS ONE, 2014;9(5):e96615.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  130. Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs.
    Authors: Park, Chul-Yon, Kim, Jungeun, Kweon, Jiyeon, Son, Jeong Sa, Lee, Jae Souk, Yoo, Jeong-Eu, Cho, Sung-Rae, Kim, Jong-Hoo, Kim, Jin-Soo, Kim, Dong-Woo
    Proc Natl Acad Sci U S A, 2014;111(25):9253-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  131. Suppression of the SOX2 neural effector gene by PRDM1 promotes human germ cell fate in embryonic stem cells.
    Authors: Lin, I-Ying, Chiu, Feng-Lan, Yeang, Chen-Hsi, Chen, Hsin-Fu, Chuang, Ching-Yu, Yang, Shii-Yi, Hou, Pei-Shan, Sintupisut, Nardnisa, Ho, Hong-Ner, Kuo, Hung-Chi, Lin, Kuo-I
    Stem Cell Reports, 2014;2(2):189-204.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  132. Identification and purification of human induced pluripotent stem cell-derived atrial-like cardiomyocytes based on sarcolipin expression.
    Authors: Josowitz, Rebecca, Lu, Jia, Falce, Christin, D'Souza, Sunita L, Wu, Meng, Cohen, Ninette, Dubois, Nicole C, Zhao, Yong, Sobie, Eric A, Fishman, Glenn I, Gelb, Bruce D
    PLoS ONE, 2014;9(7):e101316.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  133. CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis.
    Authors: Todaro M, Gaggianesi M, Catalano V, Benfante A, Iovino F, Biffoni M, Apuzzo T, Sperduti I, Volpe S, Cocorullo G, Gulotta G, Dieli F, De Maria R, Stassi G
    Cell Stem Cell, 2014;14(3):342-56.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  134. CCAAT/enhancer binding protein-mediated regulation of TGFbeta receptor 2 expression determines the hepatoblast fate decision.
    Authors: Takayama K, Kawabata K, Nagamoto Y, Inamura M, Ohashi K, Okuno H, Yamaguchi T, Tashiro K, Sakurai F, Hayakawa T, Okano T, Furue M, Mizuguchi H
    Development, 2014;141(1):91-100.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  135. BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells.
    Authors: Srikanth, Maya, Kim, Juno, Das, Sunit, Kessler, John A
    Mol Cancer Res, 2014;12(2):283-94.
  136. Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm.
    Authors: Takahashi K, Tanabe K, Ohnuki M, Narita M, Sasaki A, Yamamoto M, Nakamura M, Sutou K, Osafune K, Yamanaka S
    Nat Commun, 2014;5(0):3678.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  137. Twisted gastrulation, a BMP antagonist, exacerbates podocyte injury.
    Authors: Yamada, Sachiko, Nakamura, Jin, Asada, Misako, Takase, Masayuki, Matsusaka, Taiji, Iguchi, Taku, Yamada, Ryo, Tanaka, Mari, Higashi, Atsuko Y, Okuda, Tomohiko, Asada, Nariaki, Fukatsu, Atsushi, Kawachi, Hiroshi, Graf, Daniel, Muso, Eri, Kita, Toru, Kimura, Takeshi, Pastan, Ira, Economides, Aris N, Yanagita, Motoko
    PLoS ONE, 2014;9(2):e89135.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  138. Derivation and expansion of PAX7-positive muscle progenitors from human and mouse embryonic stem cells.
    Authors: Shelton M, Metz J, Liu J, Carpenedo R, Demers S, Stanford W, Skerjanc I
    Stem Cell Reports, 2014;3(3):516-29.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  139. Molecular beacon-enabled purification of living cells by targeting cell type-specific mRNAs.
    Authors: Wile B, Ban K, Yoon Y, Bao G
    Nat Protoc, 2014;9(10):2411-24.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  140. Broad T-cell receptor repertoire in T-lymphocytes derived from human induced pluripotent stem cells.
    Authors: Chang C, Lai Y, Lamb L, Townes T
    PLoS ONE, 2014;9(5):e97335.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  141. Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification.
    Authors: Culbert A, Chakkalakal S, Theosmy E, Brennan T, Kaplan F, Shore E
    Stem Cells, 2014;32(5):1289-300.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  142. Enzyme-free passage of human pluripotent stem cells by controlling divalent cations.
    Authors: Ohnuma, Kiyoshi, Fujiki, Ayaka, Yanagihara, Kana, Tachikawa, Saoko, Hayashi, Yohei, Ito, Yuzuru, Onuma, Yasuko, Chan, Techuan, Michiue, Tatsuo, Furue, Miho K, Asashima, Makoto
    Sci Rep, 2014;4(0):4646.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  143. HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin.
    Authors: Watanabe, Hitoshi, Takayama, Kazuo, Inamura, Mitsuru, Tachibana, Masashi, Mimura, Natsumi, Katayama, Kazufumi, Tashiro, Katsuhis, Nagamoto, Yasuhito, Sakurai, Fuminori, Kawabata, Kenji, Furue, Miho Kus, Mizuguchi, Hiroyuki
    PLoS ONE, 2014;9(3):e90791.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  144. The role of Hath6, a newly identified shear-stress-responsive transcription factor, in endothelial cell differentiation and function.
    Authors: Fang F, Wasserman S, Torres-Vazquez J, Weinstein B, Cao F, Li Z, Wilson K, Yue W, Wu J, Xie X, Pei X
    J Cell Sci, 2014;127(0):1428-40.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  145. Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa.
    Authors: Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, Keene D, Liu L, Osborn M, Lund T, Blazar B, Wagner J
    J Invest Dermatol, 2014;134(5):1246-54.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  146. MicroRNA-155 controls RB phosphorylation in normal and malignant B lymphocytes via the noncanonical TGF-beta1/SMAD5 signaling module.
    Authors: Jiang D, Aguiar R
    Blood, 2014;123(1):86-93.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  147. A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear.
    Authors: Mann Z, Thiede B, Chang W, Shin J, May-Simera H, Lovett M, Corwin J, Kelley M
    Nat Commun, 2014;5(0):3839.
    Species: Chicken
    Sample Type: Whole Cells
    Application: Bioassay
  148. Inhibition of bone morphogenic protein 4 restores endothelial function in db/db diabetic mice.
    Authors: Zhang Y, Liu J, Tian X, Wong W, Chen Y, Wang L, Luo J, Cheang W, Lau C, Kwan K, Wang N, Yao X, Huang Y
    Arterioscler Thromb Vasc Biol, 2014;34(1):152-9.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: Bioassay
  149. NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation.
    Authors: Mahadevan, Sangeeth, Wen, Shu, Wan, Ying-Woo, Peng, Hsiu-Hue, Otta, Subhendu, Liu, Zhandong, Iacovino, Michelin, Mahen, Elisabet, Kyba, Michael, Sadikovic, Bekim, Van den Veyver, Ignatia
    Hum Mol Genet, 2014;23(3):706-16.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  150. Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells.
    Authors: Taguchi A, Kaku Y, Ohmori T, Sharmin S, Ogawa M, Sasaki H, Nishinakamura R
    Cell Stem Cell, 2014;14(1):53-67.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  151. Cobalt protoporphyrin pretreatment protects human embryonic stem cell-derived cardiomyocytes from hypoxia/reoxygenation injury in vitro and increases graft size and vascularization in vivo.
    Authors: Luo J, Weaver M, Cao B, Dennis J, Van Biber B, Laflamme M, Allen M
    Stem Cells Transl Med, 2014;3(6):734-44.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  152. Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling.
    Authors: Kim W, Zhu Y, Deng Q, Chin C, He C, Grieco A, Dravid G, Parekh C, Hollis R, Lane T, Bouhassira E, Kohn D, Crooks G
    Stem Cells, 2014;32(6):1503-14.
  153. Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant.
    Authors: Takebe, Takanori, Zhang, Ran-Ran, Koike, Hiroyuki, Kimura, Masaki, Yoshizawa, Emi, Enomura, Masahiro, Koike, Naoto, Sekine, Keisuke, Taniguchi, Hideki
    Nat Protoc, 2014;9(2):396-409.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  154. BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors.
    Authors: Tsuchida, R, Osawa, T, Wang, F, Nishii, R, Das, B, Tsuchida, S, Muramatsu, M, Takahashi, T, Inoue, T, Wada, Y, Minami, T, Yuasa, Y, Shibuya, M
    Oncogene, 2014;33(29):3803-11.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  155. Focal transplantation of human iPSC-derived glial-rich neural progenitors improves lifespan of ALS mice.
    Authors: Kondo T, Funayama M, Tsukita K, Hotta A, Yasuda A, Nori S, Kaneko S, Nakamura M, Takahashi R, Okano H, Yamanaka S, Inoue H
    Stem Cell Reports, 2014;3(2):242-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  156. Characterization of stem-like cells in mucoepidermoid tracheal paediatric tumor.
    Authors: Lim M, Ooi B, Jungebluth P, Sjoqvist S, Hultman I, Lemon G, Gustafsson Y, Asmundsson J, Baiguera S, Douagi I, Gilevich I, Popova A, Haag J, Rodriguez A, Lim J, Lieden A, Nordenskjold M, Alici E, Baker D, Unger C, Luedde T, Vassiliev I, Inzunza J, Ahrlund-Richter L, Macchiarini P
    PLoS ONE, 2014;9(9):e107712.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  157. SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion.
    Authors: Cabrera-Sharp V, Read J, Richardson S, Kowalski A, Antczak D, Cartwright J, Mukherjee A, de Mestre A
    Endocrinology, 2014;155(8):3054-64.
    Species: Equine
    Sample Type: Whole Cells
    Application: Bioassay
  158. Generation of folliculogenic human epithelial stem cells from induced pluripotent stem cells.
    Authors: Yang, Ruifeng, Zheng, Ying, Burrows, Michelle, Liu, Shujing, Wei, Zhi, Nace, Arben, Guo, Wei, Kumar, Suresh, Cotsarelis, George, Xu, Xiaowei
    Nat Commun, 2014;5(0):3071.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  159. Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis.
    Authors: Morishima, Tatsuya, Watanabe, Ken-ichi, Niwa, Akira, Hirai, Hideyo, Saida, Satoshi, Tanaka, Takayuki, Kato, Itaru, Umeda, Katsutsu, Hiramatsu, Hidefumi, Saito, Megumu K, Matsubara, Kousaku, Adachi, Souichi, Kobayashi, Masao, Nakahata, Tatsutos, Heike, Toshio
    Haematologica, 2014;99(1):19-27.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  160. Functional assessment of hematopoietic niche cells derived from human embryonic stem cells.
    Authors: Ferrell, Patrick, Hexum, Melinda, Kopher, Ross A, Lepley, Michael, Gussiaas, Amanda, Kaufman, Dan S
    Stem Cells Dev, 2014;23(12):1355-63.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  161. Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes.
    Authors: Takayama K, Nagamoto Y, Mimura N, Tashiro K, Sakurai F, Tachibana M, Hayakawa T, Kawabata K, Mizuguchi H
    Stem Cell Reports, 2013;1(4):322-35.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  162. KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.
    Authors: Goldman O, Han S, Sourisseau M, Dziedzic N, Hamou W, Corneo B, D'Souza S, Sato T, Kotton D, Bissig K, Kalir T, Jacobs A, Evans T, Evans M, Gouon-Evans V
    Cell Stem Cell, 2013;12(6):748-60.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  163. Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells.
    Authors: Lee J, Sugiyama T, Liu Y, Wang J, Gu X, Lei J, Markmann J, Miyazaki S, Miyazaki J, Szot G, Bottino R, Kim S
    Elife, 2013;2(0):e00940.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  164. Production of hepatocyte-like cells from human pluripotent stem cells.
    Authors: Hannan, Nicholas, Segeritz, Charis-P, Touboul, Thomas, Vallier, Ludovic
    Nat Protoc, 2013;8(2):430-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  165. Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.
    Authors: Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel C, Hoing S, Moritz S, Parga J, Wagner L, Bruder J, Wu G, Schmid B, Ropke A, Klingauf J, Schwamborn J, Gasser T, Scholer H, Sterneckert J
    PLoS ONE, 2013;8(3):e59252.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  166. Blockade of Smad signaling by 3'-deoxyadenosine: a mechanism for its anti-fibrotic potential.
    Authors: Gu L, Johno H, Nakajima S, Kato H, Takahashi S, Katoh R, Kitamura M
    Lab Invest, 2013;93(4):450-61.
    Species: Rat
    Sample Type: Whole Cells
    Application: Bioassay
  167. A human Dravet syndrome model from patient induced pluripotent stem cells.
    Authors: Higurashi N, Uchida T, Lossin C, Misumi Y, Okada Y, Akamatsu W, Imaizumi Y, Zhang B, Nabeshima K, Mori M, Katsurabayashi S, Shirasaka Y, Okano H, Hirose S
    Mol Brain, 2013;6(0):19.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  168. TGF-beta-induced apoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD20.
    Authors: Kawabata K, Ehata S, Komuro A, Takeuchi K, Miyazono K
    Oncogene, 2013;32(16):2096-106.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  169. Generation of human induced pluripotent stem cells using epigenetic regulators reveals a germ cell-like identity in partially reprogrammed colonies.
    Authors: Goyal, Akshi, Chavez, Shawn L, Reijo Pera, Renee A
    PLoS ONE, 2013;8(12):e82838.
    Species: Human
    Sample Type: Whole Cells
    Application: cell culture
  170. BMP4 is a peripherally-derived factor for motor neurons and attenuates glutamate-induced excitotoxicity in vitro.
    Authors: Chou H, Lai D, Huang C, McLennan I, Wang H, Wang P
    PLoS ONE, 2013;8(3):e58441.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  171. Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays.
    Authors: Navarrete E, Liang P, Lan F, Sanchez-Freire V, Simmons C, Gong T, Sharma A, Burridge P, Patlolla B, Lee A, Wu H, Beygui R, Wu S, Robbins R, Bers D, Wu J
    Circulation, 2013;128(11):S3-13.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  172. Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells.
    Authors: White M, Rufaihah A, Liu L, Ghebremariam Y, Ivey K, Cooke J, Srivastava D
    Stem Cells, 2013;31(1):92-103.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  173. Functional link between bone morphogenetic proteins and insulin-like peptide 3 signaling in modulating ovarian androgen production.
    Authors: Glister C, Satchell L, Bathgate R, Wade J, Dai Y, Ivell R, Anand-Ivell R, Rodgers R, Knight P
    Proc Natl Acad Sci U S A, 2013;110(15):E1426-35.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  174. Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential.
    Authors: Duggal G, Heindryckx B, Warrier S, O'Leary T, Van der Jeught M, Lierman S, Vossaert L, Deroo T, Deforce D, Chuva de Sousa Lopes S, De Sutter P
    Stem Cells Dev, 2013;22(23):3141-55.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  175. Generation of megakaryocytic progenitors from human embryonic stem cells in a feeder- and serum-free medium.
    Authors: Pick M, Azzola L, Osborne E, Stanley E, Elefanty A
    PLoS ONE, 2013;8(2):e55530.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  176. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.
    Authors: Doulatov S, Vo L, Chou S, Kim P, Arora N, Li H, Hadland B, Bernstein I, Collins J, Zon L, Daley G
    Cell Stem Cell, 2013;13(4):459-70.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  177. Bone morphogenetic protein-2/-4 upregulation promoted by endothelial cells in coculture enhances mouse embryoid body differentiation.
    Authors: Talavera-Adame, Dodanim, Gupta, Ankur, Kurtovic, Silvia, Chaiboonma, Kira L, Arumugaswami, Vaithili, Dafoe, Donald C
    Stem Cells Dev, 2013;22(24):3252-60.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  178. Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
    Authors: Liang, Ping, Lan, Feng, Lee, Andrew S, Gong, Tingyu, Sanchez-Freire, Veronica, Wang, Yongming, Diecke, Sebastia, Sallam, Karim, Knowles, Joshua W, Wang, Paul J, Nguyen, Patricia, Bers, Donald M, Robbins, Robert C, Wu, Joseph C
    Circulation, 2013;127(16):1677-91.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  179. Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue.
    Authors: Deschaseaux F, Gaillard J, Langonne A, Chauveau C, Naji A, Bouacida A, Rosset P, Heymann D, De Pinieux G, Rouas-Freiss N, Sensebe L
    FASEB J, 2013;27(8):2977-87.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  180. Identification of small molecule activators of BMP signaling.
    Authors: Vrijens K, Lin W, Cui J, Farmer D, Low J, Pronier E, Zeng F, Shelat A, Guy K, Taylor M, Chen T, Roussel M
    PLoS ONE, 2013;8(3):e59045.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  181. A low-molecular-weight compound K7174 represses hepcidin: possible therapeutic strategy against anemia of chronic disease.
    Authors: Fujiwara, Tohru, Ikeda, Takashi, Nagasaka, Yuki, Okitsu, Yoko, Katsuoka, Yuna, Fukuhara, Noriko, Onishi, Yasushi, Ishizawa, Kenichi, Ichinohasama, Ryo, Tomosugi, Naohisa, Harigae, Hideo
    PLoS ONE, 2013;8(9):e75568.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  182. Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal.
    Authors: Wang Y, Xu Z, Jiang J, Xu C, Kang J, Xiao L, Wu M, Xiong J, Guo X, Liu H
    Dev Cell, 2013;25(1):69-80.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  183. Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells.
    Authors: Kohler, Erin E, Wary, Kishore, Li, Fei, Chatterjee, Ishita, Urao, Norifumi, Toth, Peter T, Ushio-Fukai, Masuko, Rehman, Jalees, Park, Changwon, Malik, Asrar B
    PLoS ONE, 2013;8(12):e85549.
    Species: Mouse
    Sample Type: Whole Cells
    Application: cell culture
  184. Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma.
    Authors: Huse K, Bakkebo M, Walchli S, Oksvold M, Hilden V, Forfang L, Bredahl M, Liestol K, Alizadeh A, Smeland E, Myklebust J
    PLoS ONE, 2012;7(10):e46117.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  185. Antagonism of Nodal signaling by BMP/Smad5 prevents ectopic primitive streak formation in the mouse amnion.
    Authors: Pereira P, Dobreva M, Maas E, Cornelis F, Moya I, Umans L, Verfaillie C, Camus A, de Sousa Lopes S, Huylebroeck D, Zwijsen A
    Development, 2012;139(18):3343-54.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  186. Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs).
    Authors: Wu, Qifang, Sun, Chia Chi, Lin, Herbert, Babitt, Jodie L
    PLoS ONE, 2012;7(9):e46307.
    Species: Human
    Sample Type: Recombinant Protein
    Application: Surface Plasmon Resonance
  187. Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
    Gene Ther, 2012;19(10):1035-40.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  188. The endothelial cell line bEnd.3 maintains human pluripotent stem cells.
    Authors: Joubin, Katherin, Richardson, Amelia, Novoa, Natalia, Tu, Edmund, Tomishima, Mark J
    Stem Cells Dev, 2012;21(12):2312-21.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  189. Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium.
    Authors: Yao Y, Jumabay M, Ly A, Radparvar M, Wang AH, Abdmaulen R, Bostrom KI
    Blood, 2012;119(21):5037-47.
    Species: Human
    Sample Type: Cell Lysates
    Application: Bioassay
  190. Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility.
    Authors: Cheung C, Bernardo AS, Trotter MW
    Nat. Biotechnol., 2012;30(2):165-73.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  191. Gremlin-1 induces BMP-independent tumor cell proliferation, migration, and invasion.
    Authors: Kim M, Yoon S, Lee S
    PLoS ONE, 2012;7(4):e35100.
    Species: Human
    Sample Type: Recombinant Protein
    Application: Binding Assay
  192. The hedgehog system in ovarian follicles of cattle selected for twin ovulations and births: evidence of a link between the IGF and hedgehog systems.
    Authors: Aad, Pauline, Echternkamp, Sherrill, Sypherd, David D, Schreiber, Nicole B, Spicer, Leon J
    Biol Reprod, 2012;87(4):79.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  193. Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma.
    Authors: Maegdefrau U, Arndt S, Kivorski G, Hellerbrand C, Bosserhoff AK
    Lab. Invest., 2011;91(11):1615-23.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  194. Down-regulation of Kruppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-{beta} and Bone Morphogenetic Protein 4.
    Authors: Davis-Dusenbery BN, Chan MC, Reno KE, Weisman AS, Layne MD, Lagna G, Hata A
    J. Biol. Chem., 2011;286(32):28097-110.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  195. A small peptide modeled after the NRAGE repeat domain inhibits XIAP-TAB1-TAK1 signaling for NF-kappaB activation and apoptosis in P19 cells.
    Authors: Rochira JA, Matluk NN, Adams TL, Karaczyn AA, Oxburgh L, Hess ST, Verdi JM
    PLoS ONE, 2011;6(7):e20659.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  196. Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth.
    Authors: Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV
    J. Biol. Chem., 2011;286(34):30034-46.
    Species: Human
    Sample Type: Recombinant Protein
    Application: Surface Plasmon Resonance
  197. Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7.
    Authors: Huse K, Bakkebo M, Oksvold MP, Forfang L, Hilden VI, Stokke T, Smeland EB, Myklebust JH
    Eur. J. Immunol., 2011;41(11):3135-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  198. Sertoli cell-conditioned medium induces germ cell differentiation in human embryonic stem cells.
    Authors: Geens M, Sermon KD
    J. Assist. Reprod. Genet., 2011;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  199. A novel role for an RNA polymerase III subunit POLR3G in regulating pluripotency in human embryonic stem cells.
    Authors: Wong RC, Pollan S, Fong H, Ibrahim A, Smith EL, Ho M, Laslett AL, Donovan PJ
    Stem Cells, 2011;29(10):1517-27.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  200. Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals.
    Authors: Zhang Q, Jiang J, Han P, Yuan Q, Zhang J, Zhang X, Xu Y, Cao H, Meng Q, Chen L, Tian T, Wang X, Li P, Hescheler J, Ji G, Ma Y
    Cell Res., 2011;21(4):579-87.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  201. Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome).
    Authors: Tolar J, Park I, Xia L, Lees C, Peacock B, Webber B, McElmurry R, Eide C, Orchard P, Kyba M, Osborn M, Lund T, Wagner J, Daley G, Blazar B
    Blood, 2011;117(3):839-47.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  202. A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors.
    Authors: Niwa A, Heike T, Umeda K
    PLoS ONE, 2011;6(7):e22261.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  203. Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells.
    Authors: Roelandt P, Pauwelyn KA, Sancho-Bru P
    PLoS ONE, 2010;5(8):e12101.
    Species: Human
    Sample Type: Whole Cells
    Application: Expansion/Differentiation
  204. SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
    Authors: Chng Z, Teo A, Pedersen RA, Vallier L
    Cell Stem Cell, 2010;6(1):59-70.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  205. Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state.
    Authors: Lanner F, Lee KL, Sohl M, Holmborn K, Yang H, Wilbertz J, Poellinger L, Rossant J, Farnebo F
    Stem Cells, 2010;28(2):191-200.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  206. A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
    Authors: Klim JR, Li L, Wrighton PJ
    Nat. Methods, 2010;7(12):989-94.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  207. The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain.
    Authors: Martino MM, Hubbell JA
    FASEB J., 2010;24(12):4711-21.
    Species: Human
    Sample Type: Recombinant Protein
    Application: Surface Plasmon Resonance
  208. Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis.
    Authors: Rai D, Kim SW, McKeller MR
    Proc. Natl. Acad. Sci. U.S.A., 2010;107(7):3111-6.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  209. BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling pathway.
    Authors: Stewart A, Guan H, Yang K
    J. Cell. Physiol., 2010;223(3):658-66.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  210. Bone morphogenetic proteins and receptors are over-expressed in bone-marrow cells of multiple myeloma patients and support myeloma cells by inducing ID genes.
    Authors: Grcevic D, Kusec R, Kovacic N, Lukic A, Lukic IK, Ivcevic S, Nemet D, Seiwerth RS, Ostojic SK, Croucher PI, Marusic A
    Leuk. Res., 2010;34(6):742-51.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  211. Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.
    Authors: Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K
    Stem Cells, 2009;27(2):341-51.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  212. Fibroblast growth factors and epidermal growth factor cooperate with oocyte-derived members of the TGFbeta superfamily to regulate Spry2 mRNA levels in mouse cumulus cells.
    Authors: Sugiura K, Su YQ, Li Q, Wigglesworth K, Matzuk MM, Eppig JJ
    Biol. Reprod., 2009;81(5):833-41.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  213. Signaling hierarchy regulating human endothelial cell development.
    Authors: Kelly MA, Hirschi KK
    Arterioscler. Thromb. Vasc. Biol., 2009;29(5):718-24.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  214. Scaffold-free human cardiac tissue patch created from embryonic stem cells.
    Authors: Stevens KR, Pabon L, Muskheli V
    Tissue Eng Part A, 2009;15(6):1211-22.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  215. GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses.
    Authors: Levine AJ, Levine ZJ, Brivanlou AH
    Dev. Biol., 2009;325(1):43-8.
    Species: Xenopus
    Sample Type: Whole Cells
    Application: Bioassay
  216. Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases.
    Authors: Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW
    Proc. Natl. Acad. Sci. U.S.A., 2009;106(24):9826-30.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  217. Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells.
    Authors: Tanno T, Porayette P, Sripichai O, Noh SJ, Byrnes C, Bhupatiraju A, Lee YT, Goodnough JB, Harandi O, Ganz T, Paulson RF, Miller JL
    Blood, 2009;114(1):181-6.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  218. A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum.
    Authors: Herrera B, Inman GJ,
    BMC Cell Biol., 2009;10(0):20.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  219. Postinjury niches induce temporal shifts in progenitor fates to direct lesion repair after spinal cord injury.
    Authors: Sellers DL, Maris DO, Horner PJ
    J. Neurosci., 2009;29(20):6722-33.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  220. Combinatorial signals of activin/nodal and bone morphogenic protein regulate the early lineage segregation of human embryonic stem cells.
    Authors: Wu Z, Zhang W, Chen G, Cheng L, Liao J, Jia N, Gao Y, Dai H, Yuan J, Cheng L, Xiao L
    J. Biol. Chem., 2008;283(36):24991-5002.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  221. Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis.
    Authors: Kane R, Godson C, O'Brien C
    Mol. Vis., 2008;14(0):1138-48.
    Species: Human
    Sample Type: Cell Lysates
    Application: Binding Assay
  222. Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture.
    Authors: Sun Y, Pollard S, Conti L, Toselli M, Biella G, Parkin G, Willatt L, Falk A, Cattaneo E, Smith A
    Mol. Cell. Neurosci., 2008;38(2):245-58.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  223. Targeting of bone morphogenetic protein growth factor complexes to fibrillin.
    Authors: Sengle G, Charbonneau NL, Ono RN, Sasaki T, Alvarez J, Keene DR, Bachinger HP, Sakai LY
    J. Biol. Chem., 2008;283(20):13874-88.
    Species: Human
    Sample Type: Recombinant Protein
    Application: complex formation
  224. Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins.
    Authors: Chen G, Ye Z, Yu X, Zou J, Mali P, Brodsky RA, Cheng L
    Cell Stem Cell, 2008;2(4):345-55.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  225. Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.
    Authors: Saeki K, Yogiashi Y, Nakahara M, Nakamura N, Matsuyama S, Koyanagi A, Yagita H, Koyanagi M, Kondo Y, Yuo A
    J. Cell. Physiol., 2008;217(1):261-80.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Type: Whole Cells
    Application: Bioassay
  226. Regulation of bone morphogenetic protein signalling in human pulmonary vascular development.
    Authors: Southwood M, Jeffery TK, Yang X, Upton PD, Hall SM, Atkinson C, Haworth SG, Stewart S, Reynolds PN, Long L, Trembath RC, Morrell NW
    J. Pathol., 2008;214(1):85-95.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  227. Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus.
    Authors: Anderson BC, Christiansen SP, McLoon LK
    Invest. Ophthalmol. Vis. Sci., 2008;49(1):221-9.
    Species: Rabbit
    Sample Type: In Vivo
    Application: In Vivo
  228. High-density lipoproteins affect endothelial BMP-signaling by modulating expression of the activin-like kinase receptor 1 and 2.
    Authors: Yao Y, Shao ES, Jumabay M, Shahbazian A, Ji S, Bostrom KI
    Arterioscler. Thromb. Vasc. Biol., 2008;28(12):2266-74.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  229. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.
    Authors: Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR
    Nature, 2008;454(7207):1000-4.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  230. Cross-talk between fibroblast growth factor and bone morphogenetic proteins regulates gap junction-mediated intercellular communication in lens cells.
    Authors: Boswell BA, Lein PJ, Musil LS
    Mol. Biol. Cell, 2008;19(6):2631-41.
    Species: Chicken
    Sample Type: Whole Tissue
    Application: Bioassay
  231. Essential role of BMPs in FGF-induced secondary lens fiber differentiation.
    Authors: Boswell BA, Overbeek PA, Musil LS
    Dev. Biol., 2008;324(2):202-12.
    Species: Chicken
    Sample Type: Whole Cells
    Application: Bioassay
  232. BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling.
    Authors: Jeanpierre S, Nicolini FE, Kaniewski B, Dumontet C, Rimokh R, Puisieux A, Maguer-Satta V
    Blood, 2008;112(8):3154-63.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  233. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
    Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM
    Nature, 2008;453(7194):524-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  234. Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage.
    Authors: Elkabetz Y, Panagiotakos G, Al Shamy G, Socci ND, Tabar V, Studer L
    Genes Dev., 2008;22(2):152-65.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  235. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
    Authors: Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
    Cell Stem Cell, 2008;2(6):602-12.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  236. Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.
    Authors: Lin L, Valore EV, Nemeth E, Goodnough JB, Gabayan V, Ganz T
    Blood, 2007;110(6):2182-9.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  237. Predicting evolutionary patterns of mammalian teeth from development.
    Authors: Kavanagh KD, Evans AR, Jernvall J
    Nature, 2007;449(7161):427-32.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: Bioassay
  238. Bone morphogenetic proteins promote gliosis in demyelinating spinal cord lesions.
    Authors: Fuller ML, DeChant AK, Rothstein B, Caprariello A, Wang R, Hall AK, Miller RH
    Ann. Neurol., 2007;62(3):288-300.
  239. New cell lines from mouse epiblast share defining features with human embryonic stem cells.
    Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD
    Nature, 2007;448(7150):196-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  240. A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification.
    Authors: Stavridis MP, Lunn JS, Collins BJ, Storey KG
    Development, 2007;134(16):2889-94.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  241. Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor.
    Authors: Stabile H, Mitola S, Moroni E, Belleri M, Nicoli S, Coltrini D, Peri F, Pessi A, Orsatti L, Talamo F, Castronovo V, Waltregny D, Cotelli F, Ribatti D, Presta M
    Blood, 2007;109(5):1834-40.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  242. Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells.
    Authors: Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H
    Blood, 2007;111(4):1933-41.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  243. Activation of the BMP canonical signaling pathway in human optic nerve head tissue and isolated optic nerve head astrocytes and lamina cribrosa cells.
    Authors: Zode GS, Clark AF, Wordinger RJ
    Invest. Ophthalmol. Vis. Sci., 2007;48(11):5058-67.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  244. Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
    Authors: Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S
    Cell, 2007;131(5):861-72.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  245. Thalidomide induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling pathway.
    Authors: Knobloch J, Shaughnessy JD, Ruther U
    FASEB J., 2007;21(7):1410-21.
    Species: Chicken
    Sample Type: Whole Cells
    Application: Bioassay
  246. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.
    Authors: Rajesh&lt;/LastName&gt;&lt;ForeNam D&lt;/Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF
    Stem Cells, 2007;25(2):490-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  247. Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells.
    Authors: Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, Izawa K, Dong Y, Hashiguchi T, Soda Y, Maeda T, Suehiro Y, Tanioka Y, Nakazaki Y, Tani K
    Stem Cells, 2006;24(9):2014-22.
    Species: Primate - Callitrix jacchus (Common Marmoset)
    Sample Type: Whole Cells
    Application: Bioassay
  248. Inhibitory Smad transcription factors protect arterial endothelial cells from apoptosis induced by BMP4.
    Authors: Kiyono M, Shibuya M
    Oncogene, 2006;25(54):7131-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  249. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.
    Authors: Lindsley RC, Gill JG, Kyba M, Murphy TL, Murphy KM
    Development, 2006;133(19):3787-96.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  250. BMPs restrict the position of premuscle masses in the limb buds by influencing Tcf4 expression.
    Authors: Bonafede A, Kohler T, Rodriguez-Niedenfuhr M, Brand-Saberi B
    Dev. Biol., 2006;299(2):330-44.
    Species: Chicken
    Sample Type: In Ovo
    Application: In Ovo
  251. Multipotent adult progenitor cells from swine bone marrow.
    Authors: Zeng L, Rahrmann E, Hu Q, Lund T, Sandquist L, Felten M, O'Brien TD, O'Brien TD, Zhang J, Verfaillie C
    Stem Cells, 2006;24(11):2355-66.
    Species: Porcine
    Sample Type: Whole Cells
    Application: Bioassay
  252. Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct.
    Authors: Maeshima A, Vaughn DA, Choi Y, Nigam SK
    Dev. Biol., 2006;295(2):473-85.
    Species: Rat
    Sample Type: Whole Tissue
    Application: Bioassay
  253. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.
    Authors: Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S
    Proc. Natl. Acad. Sci. U.S.A., 2006;103(18):6907-12.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  254. Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis.
    Authors: Ikeya M, Kawada M, Kiyonari H, Sasai N, Nakao K, Furuta Y, Sasai Y
    Development, 2006;133(22):4463-73.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  255. Growth differentiation factor-9 has divergent effects on proliferation and steroidogenesis of bovine granulosa cells.
    Authors: Spicer LJ, Aad PY, Allen D, Mazerbourg S, Hsueh AJ
    J. Endocrinol., 2006;189(2):329-39.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  256. Regulation of ADMP and BMP2/4/7 at opposite embryonic poles generates a self-regulating morphogenetic field.
    Authors: Reversade B, De Robertis EM
    Cell, 2005;123(6):1147-60.
    Species: Xenopus
    Sample Type: In Vivo
    Application: In Vivo
  257. Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer.
    Authors: Ng RK, Gurdon JB
    Proc. Natl. Acad. Sci. U.S.A., 2005;102(6):1957-62.
    Species: Xenopus
    Sample Type: Whole Cells
    Application: Bioassay
  258. Requirements for endoderm and BMP signaling in sensory neurogenesis in zebrafish.
    Authors: Holzschuh J, Wada N, Wada C, Schaffer A, Javidan Y, Tallafuss A, Bally-Cuif L, Schilling TF
    Development, 2005;132(16):3731-42.
    Species: Xenopus
    Sample Type: In Vivo
    Application: In Vivo
  259. Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins.
    Authors: Binnerts ME, Wen X, Cante-Barrett K, Bright J, Chen HT, Asundi V, Sattari P, Tang T, Boyle B, Funk W, Rupp F
    Biochem. Biophys. Res. Commun., 2004;315(2):272-80.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  260. Cutting edge: bone morphogenetic protein antagonists Drm/Gremlin and Dan interact with Slits and act as negative regulators of monocyte chemotaxis.
    Authors: Blair DG, Plisov S, Vasiliev G, Perantoni AO, Athanasiou M, Wu JY, Oppenheim JJ
    J. Immunol., 2004;173(10):5914-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  261. hCHL2, a novel chordin-related gene, displays differential expression and complex alternative splicing in human tissues and during myoblast and osteoblast maturation.
    Authors: Oren A, Toporik A, Biton S, Almogy N, Eshel D, Bernstein J, Savitsky K, Rotman G
    Gene, 2004;331(0):17-31.
    Species: Human
    Sample Type:
    Application: Bioassay
  262. Blocked MAP kinase activity selectively enhances neurotrophic growth responses.
    Authors: Althini S, Usoskin D, Kylberg A, Kaplan PL, Ebendal T
    Mol. Cell. Neurosci., 2004;25(2):345-54.
    Species: Chicken
    Sample Type: Whole Cells
    Application: Bioassay
  263. Molecular basis of bone morphogenetic protein-4 inhibitory action on progesterone secretion by ovine granulosa cells.
    Authors: Pierre A, Pisselet C, Dupont J, Mandon-Pepin B, Monniaux D, Monget P, Fabre S
    J. Mol. Endocrinol., 2004;33(3):805-17.
    Species: Ovine
    Sample Type: Whole Cells
    Application: Bioassay
  264. Retinoic acid signalling specifies intermediate character in the developing telencephalon.
    Authors: Marklund M, Sjodal M, Beehler BC, Jessell TM, Edlund T, Gunhaga L
    Development, 2004;131(17):4323-32.
    Species: Chicken
    Sample Type: Whole Tissue
    Application: Bioassay
  265. Multiple roles of Sox2, an HMG-box transcription factor in avian neural crest development.
    Authors: Wakamatsu Y, Endo Y, Osumi N, Weston JA
    Dev. Dyn., 2004;229(1):74-86.
    Species: Chicken
    Sample Type: Whole Cells
    Application: Bioassay
  266. Effect of recombinant human bone morphogenetic protein-4 with carriers in rat calvarial defects.
    Authors: Ahn SH, Kim CS, Suk HJ, Lee YJ, Choi SH, Chai JK, Kim CK, Han SB, Cho KS
    J. Periodontol., 2003;74(6):787-97.
    Species: Rat
    Sample Type: In Vivo
    Application: In Vivo
  267. BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation.
    Authors: Moser M, Binder O, Wu Y, Aitsebaomo J, Ren R, Bode C, Bautch VL, Conlon FL, Patterson C
    Mol. Cell. Biol., 2003;23(16):5664-79.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  268. Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2.
    Authors: Viti J, Gulacsi A, Lillien L
    J. Neurosci., 2003;23(13):5919-27.
    Species: Mouse
    Sample Type: Whole Tissue
    Application: Bioassay
  269. FGF8 acts as a right determinant during establishment of the left-right axis in the rabbit.
    Authors: Fischer A, Viebahn C, Blum M
    Curr. Biol., 2002;12(21):1807-16.
    Species: Rabbit
    Sample Type: Whole Cells
    Application: Bioassay
  270. Prkci is required for a non-autonomous signal that coordinates cell polarity during cavitation.
    Authors: In Kyoung Mah, Mah I, Soloff R, Izuhara A, Lakeland D, Mariani F
    Dev Biol, 0;416(1):82-97.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
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In vitro bioactivity in cell culture Recombinant Human BMP-4 Protein 314-BP Array 314-BP
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In vitro bioactivity in cell culture Recombinant Human BMP-4 Protein 314-BP
In vitro bioactivity in cell culture: Recombinant Human BMP-4 Protein [314-BP].

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