Potent analog of capsaicin that is an agonist at vanilloid receptors (Ki
= 43 pM). Like capsaicin, it acts as a selective modulator of primary afferent neurons. Also available as part of the Vanilloid TRPV1 Receptor Tocriset™
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Distinct structure-activity relations for stimulation of 45Ca uptake and for high affinity binding in cultured rat dorsal root ganglion neurons and dorsal root ganglion membranes.
Acs et al.
Brain Res.Mol.Brain Res., 1996;35:173
Cellular mechanism of action of resiniferatoxin: a potent sensory neuron excitotoxin.
Winter et al.
Brain Res., 1990;520:131
Resiniferatoxin: an ultrapotent selective modulator of capsaicin-sensitive primary afferent neurons.
Szolcsanyi et al.
The citations listed below are publications that use Tocris products. Selected citations for Resiniferatoxin include:
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