A phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC
M) and displays mixed agonist/antagonist actions at ER
estrogen receptors. Converted into the anticancer agent
(Cat. No. 1554) by cytochrome P450 1B1. Activates autophagy.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Therapeutic potential of resveratrol: the in vivo evidence.
Baur and Sinclair
Nat.Rev.Drug Discov., 2006;5:493
Resveratrol acts as a mixed agonist/antagonist for estrogen receptors α and β.
Bowers et al.
Resveratrol is a selective human cytochrome P450 1A1 inhibitor.
Chun et al.
Effects of stilbenes on arachidonate metabolism in leukocytes.
Kimura et al.
Biological effects of resveratrol.
Life Sci., 2000;66:663
Regulation of histone H2A.Z exprsesion is mediated by sirtuin 1 in prostate cancer.
Baptista et al.
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.
Galluzzi et al.
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