Potent, collagenase-selective MMP inhibitor (Ki
values are 3.0, 3.4, 4.4, 59, 154 and 527 nM for MMP-1, MMP-13, MMP-8, MMP-9, MMP-2 and MMP-3 respectively). Inhibits cartilage breakdown in vitro
and in vivo
and displays antiarthritic activity. Orally active.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Ro 32-3555, an orally active collagenase inhibitor, prevents cartilage breakdown in vitro and in vivo.
Lewis et al.
Design and synthesis of the cartilage protective agent (CPA, Ro32-3555).
Broadhurst et al.
The citations listed below are publications that use Tocris products. Selected citations for Ro 32-3555 include:
Showing Results 1 - 1 of 1