S100A1 Antibody (2C8B8)

Novus Biologicals | Catalog # NB110-60530

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 2C8B8
View all S100A1 Primary Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of S100A1 expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for S100A1 Antibody (2C8B8)

Western Blot: S100A1 Antibody (2C8B8)BSA Free [NB110-60530]

Western Blot: S100A1 Antibody (2C8B8)BSA Free [NB110-60530]

Western Blot: S100A1 Antibody (2C8B8) [NB110-60530] - Analysis using S100A mouse mAb against truncated S100A recombinant protein.
Immunohistochemistry-Paraffin: S100A1 Antibody (2C8B8) - BSA Free [NB110-60530]

Immunohistochemistry-Paraffin: S100A1 Antibody (2C8B8) - BSA Free [NB110-60530]

Immunohistochemistry-Paraffin: S100A1 Antibody (2C8B8) [NB110-60530] - Analysis of human brain tissue (A), lymphoid follicles tissue (B) and interbrain tissue (C), showing cytoplasmic localization using S100A mouse mAb with DAB staining.

Applications for S100A1 Antibody (2C8B8)

Application
Recommended Usage

ELISA

1:10000

Immunohistochemistry

1:200 - 1:1000

Immunohistochemistry-Paraffin

1:200 - 1:1000

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Ascites

Formulation

Ascites

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: S100A1

S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumors of the skin, and in Langerhans cells in the skin.

Long Name

S100 Calcium Binding Protein A1

Alternate Names

protein S100-A1, S100 alpha, S100 calcium binding protein A1, S100 calcium-binding protein A1S100, S-100 protein alpha chain, S-100 protein subunit alpha, S100 protein, alpha polypeptide, S100A, S100-alpha

Entrez Gene IDs

6271 (Human)

Gene Symbol

S100A1

UniProt

P23297

Additional S100A1 Products

Product Documents for S100A1 Antibody (2C8B8)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for S100A1 Antibody (2C8B8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customer Reviews for S100A1 Antibody (2C8B8)

There are currently no reviews for this product. Be the first to review S100A1 Antibody (2C8B8) and earn rewards!

Have you used S100A1 Antibody (2C8B8)?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies