S1P4/EDG-6 Antibody (1) - C-terminus - BSA Free

Novus Biologicals | Catalog # NBP2-66579

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 1

Format

BSA Free
View all S1P4/EDG-6 Primary Antibodies »

Product Specifications

Immunogen

Hybridoma produced by the fusion of splenocytes from mice immunized with Unique synthetic peptide derived from the C-terminal of the EDG6 (S1P4) protein and mouse myeloma cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for S1P4/EDG-6 Antibody (1) - C-terminus - BSA Free

Immunocytochemistry/Immunofluorescence: S1P4/EDG-6 Antibody (1) [NBP2-66579]

Applications for S1P4/EDG-6 Antibody (1) - C-terminus - BSA Free

Application
Recommended Usage

Western Blot

5 - 10 ug/mL
Application Notes
Optimal concentration should be evaluated by serial dilutions..

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

BSA Free

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: S1P4/EDG-6

S1P4/EDG-6 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for S1P4/EDG-6 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. S1P4/EDG-6 is expressed in lymphoid and hematopoietic tissue and in the lungs. Recently, the designation of the EDG receptors has been modified to include the ligand for the receptor. Thus, the new designation for the S1P4/EDG-6 receptor is the sphingosine 1-phosphate receptor-4 (S1P4).

Long Name

Endothelial Differentiation Gene 5

Alternate Names

EDG6, S1PR4, SLP4

Gene Symbol

S1PR4

UniProt

O95977

Additional S1P4/EDG-6 Products

Product Documents for S1P4/EDG-6 Antibody (1) - C-terminus - BSA Free

Certificate of Analysis

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Product Specific Notices for S1P4/EDG-6 Antibody (1) - C-terminus - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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