[Sar⁹,Met(O₂)¹¹]-Substance P

Name: [Sar 9 ,Met(O 2 ) 11 ]-Substance P
Brand: Tocris Bioscience
SKU: 1178
Price: 227 USD
Availability: InStock

Tocris Bioscience | Catalog # 1178

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Citations (12)

Product Documents

Potent and selective NK1 agonist

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Potent and selective NK1 agonist

View all NK1 Receptor Agonists »

Product Description

[Sar⁹,Met(O₂)¹¹]-Substance P is a potent selective NK₁ tachykinin receptor agonist.

Product Specifications for [Sar⁹,Met(O₂)¹¹]-Substance P

Molecular Weight

1393.68

Formula

C₆₄H₁₀₀N₁₈O₁₅S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

110880-55-2

PubChem ID

163829

InChI Key

OUPXSLGGCPUZJJ-SARDKLJWSA-N

SMILES

[H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N(C)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCS(C)(=O)=O)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 12 publications citing the usage of this product.

Tousignant ¹²⁵I-BH[Sar⁹,Met(O₂)¹¹]-SP, a new selective ligand for the NK-1 receptor in the central nervous system. Brain Res. 1990 PMID: 1705465
King Profile of neuronal excitation following selective activation of the neurokinin-1 receptor in rat deep dorsal horn in vitro. Brain Res. 1997 PMID: 9365015
Li and Zhao Small sensory neurons in the rat dorsal root ganglia express functional NK-1 tachykinin receptor. Eur.J.Neurosci. 1998 PMID: 9749783
Cellier Characterisation of central and peripheral effects of septide with the use of five tachykinin NK₁ receptor antagonists in the rat. Br.J.Pharmacol. 1999 PMID: 10401563

Product Documents for [Sar⁹,Met(O₂)¹¹]-Substance P

Certificate of Analysis

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Download SDS

Product Specific Notices for [Sar⁹,Met(O₂)¹¹]-Substance P

For research use only

Citations for [Sar⁹,Met(O₂)¹¹]-Substance P

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