Sarafotoxin S6b
Discontinued Product
1174 has been discontinued.
View all Non-selective Endothelin Receptor Agonists products.
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Description: Endothelin receptor agonist; non-selective
Biological Activity
Vasoconstrictor peptide; non-selective endothelin receptor agonist.Technical Data
M.Wt:
2564
Formula:
C110H159N27O34S5
Sequence:
CSCKDMTDKECLYFCHQDVIW
(Modifications: Disulfide bridge between: 1-15, 3-11)
Solubility:
Soluble to 1 mg/ml in 20% acetonitrile
Storage:
Desiccate at -20°C
CAS No:
116303-65-2
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Studies on the disulfide bridges of sarafotoxins. Chemical synthesis of sarafotoxin S6B and its homologue with different disulfide bridges.
Aimoto et al.
Biochem.Int., 1990;21:1051 -
Different endothelin receptors involved in endothelin-1- and sarafotoxin S6B-induced contractions of the human isolated coronary artery.
Bax et al.
Br.J.Pharmacol., 1994;113:1471 -
Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery.
Devadason and Henry
Br.J.Pharmacol., 1997;121:253
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