Catalog Number: 1174
Biological Activity
Vasoconstrictor peptide; non-selective endothelin receptor agonist.
Technical Data
  • M.Wt:
    2564
  • Formula:
    C110H159N27O34S5
  • Sequence:
    CSCKDMTDKECLYFCHQDVIW

    (Modifications: Disulfide bridge between: 1-15, 3-11)

  • Solubility:
    Soluble to 1 mg/ml in 20% acetonitrile
  • Storage:
    Desiccate at -20°C
  • CAS No:
    116303-65-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Different endothelin receptors involved in endothelin-1- and sarafotoxin S6B-induced contractions of the human isolated coronary artery.
    Bax et al.
    Br.J.Pharmacol., 1994;113:1471
  2. Studies on the disulfide bridges of sarafotoxins. Chemical synthesis of sarafotoxin S6B and its homologue with different disulfide bridges.
    Aimoto et al.
    Biochem.Int., 1990;21:1051
  3. Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery.
    Devadason and Henry
    Br.J.Pharmacol., 1997;121:253

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