SARS-CoV-2 Spike S2 Subunit Alexa Fluor™ Plus 488‑conjugated Antibody

R&D Systems | Catalog # FAB11130AFP488

R&D Systems

Key Product Details

Species Reactivity

SARS-CoV-2

Applications

ELISA

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2812B
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Product Specifications

Specificity

Detects SARS-CoV-2 Spike S2 Subunit in direct ELISAs.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for SARS-CoV-2 Spike S2 Subunit Alexa Fluor™ Plus 488‑conjugated Antibody

Application
Recommended Usage

ELISA

Optimal dilution of this antibody should be experimentally determined.

Background: Spike S2 Subunit

Spike S2 subunit contains the C-terminal region of the coronavirus Spike protein. It contains two heptad repeat domains, HR1 and HR2, that interact to form a six-helix bundle bringing the viral membrane close to the host cell membrane allowing fusion to occur. Inhibitors that block this process have therapeutic potential and are currently being studied. In addition to the heptad repeats, there is a C-terminal transmembrane domain responsible for anchoring the Spike protein in the viral membrane and a short cytoplasmic tail.

Long Name

Spike Protein, S2 Subunit

Alternate Names

COVID-19, S2 protein, SARS-CoV-2, SARS-CoV-2 Spike, Spike glycoprotein Subunit 2, spike protein, Spike protein S2, structural protein, surface glycoprotein

Additional Spike S2 Subunit Products

Product Documents for SARS-CoV-2 Spike S2 Subunit Alexa Fluor™ Plus 488‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for SARS-CoV-2 Spike S2 Subunit Alexa Fluor™ Plus 488‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

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