Key Product Details

Species Reactivity

SARS-CoV-2

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2812B
View all Spike S2 Subunit Primary Antibodies »

Product Specifications

Immunogen

Recombinant SARS-CoV2 Spike S2 Subunit

Specificity

Detects SARS-CoV-2 Spike S2 Subunit in direct ELISAs.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for SARS-CoV-2 Spike S2 Subunit Antibody

Application
Recommended Usage

ELISA

This antibody functions as a SARS-CoV-2 Spike S2 Subunit ELISA detection antibody when paired with Catalog # MAB10850

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Spike S2 Subunit

Spike S2 subunit contains the C-terminal region of the coronavirus Spike protein. It contains two heptad repeat domains, HR1 and HR2, that interact to form a six-helix bundle bringing the viral membrane close to the host cell membrane allowing fusion to occur. Inhibitors that block this process have therapeutic potential and are currently being studied. In addition to the heptad repeats, there is a C-terminal transmembrane domain responsible for anchoring the Spike protein in the viral membrane and a short cytoplasmic tail.

Long Name

Spike Protein, S2 Subunit

Alternate Names

COVID-19, S2 protein, SARS-CoV-2, SARS-CoV-2 Spike, Spike glycoprotein Subunit 2, spike protein, Spike protein S2, structural protein, surface glycoprotein

Additional Spike S2 Subunit Products

Product Documents for SARS-CoV-2 Spike S2 Subunit Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for SARS-CoV-2 Spike S2 Subunit Antibody

For research use only

Related Research Areas

Infectious Diseases

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FAQs

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