Spike S2 subunit contains the C-terminal region of the coronavirus Spike protein. It contains two heptad repeat domains, HR1 and HR2, that interact to form a six-helix bundle bringing the viral membrane close to the host cell membrane allowing fusion to occur. Inhibitors that block this process have therapeutic potential and are currently being studied. In addition to the heptad repeats, there is a C-terminal transmembrane domain responsible for anchoring the Spike protein in the viral membrane and a short cytoplasmic tail.
SARS-CoV-2 Spike S2 Subunit Alexa Fluor™ Plus 594‑conjugated Antibody
R&D Systems | Catalog # FAB11130AFP594
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Applications for SARS-CoV-2 Spike S2 Subunit Alexa Fluor™ Plus 594‑conjugated Antibody
ELISA
Background: Spike S2 Subunit
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Additional Spike S2 Subunit Products
Product Documents for SARS-CoV-2 Spike S2 Subunit Alexa Fluor™ Plus 594‑conjugated Antibody
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Product Specific Notices for SARS-CoV-2 Spike S2 Subunit Alexa Fluor™ Plus 594‑conjugated Antibody
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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