SB 611812

Catalog # Availability Size / Price Qty
4670/10
4670/50
Cat.No. 4670 - SB 611812 | C17H16Cl3F3N2O3S | CAS No. 345892-71-9
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Description: Urotensin-II (UT) antagonist; attenuates cardiac dysfunction

Chemical Name: 2,6-Dichloro-N-[4-chloro-3-[2-(dimethylamino)ethoxy]phenyl]-4-(trifluoromethyl)benzenesulfonamide

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Biological Activity

Urotensin-II (UT) antagonist. Inhibits urotensin-II-induced proliferation of neonatal cardiac fibroblasts. Attenuates cardiac dysfunction in a rat model of coronary artery ligation; decreases cardiomyocyte hypertrophy, ventricular dilatation and cardiac remodeling.

Technical Data

Formula:
C17H16Cl3F3N2O3S
Solubility:
Soluble to 10 mM in DMSO
Storage:
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
CAS No:
345892-71-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline.

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