SENP1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-89553

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Rat (92%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: GDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGK

Reactivity Notes

Mouse (89%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SENP1 Antibody - BSA Free

SENP1 Antibody - BSA Free Immunocytochemistry/ Immunofluorescence: SENP1 Antibody - BSA Free [NBP1-89553]

Immunocytochemistry/ Immunofluorescence: SENP1 Antibody - BSA Free [NBP1-89553]

Staining of human cell line A-431 shows localization to nucleus.
Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553]

Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553]

Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553]

Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553]

Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553] - Staining of human endometrium shows moderate nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553]

Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553]

Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553] - Staining of human placenta shows moderate to strong nuclear positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553]

Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553]

Immunohistochemistry-Paraffin: SENP1 Antibody [NBP1-89553] - Staining of human skin shows moderate to strong nuclear positivity in keratinocytes.

Applications for SENP1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SENP1

Covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes.

Long Name

SUMO-Specific Peptidase 1

Alternate Names

SuPr-2

Gene Symbol

SENP1

Additional SENP1 Products

Product Documents for SENP1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for SENP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for SENP1 Antibody - BSA Free

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Protocols

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FAQs

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Associated Pathways

HIF Enhancer Pathways HIF Enhancer Pathway Thumbnail