Septin-6 Antibody

Novus Biologicals | Catalog # NBP1-83824

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all Septin-6 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KSTSQGFCFNILCVGETGIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVDTVGFGDQINKDDSYKPIVEYIDAQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Septin-6 Antibody

Septin-11 Antibody Western Blot: SNRPN Antibody [NBP1-83824]

Western Blot: SNRPN Antibody [NBP1-83824]

Analysis in human cell line SH-SY5Y.
Septin-11 Antibody Immunohistochemistry-Paraffin: Septin-11 Antibody [NBP1-83824]

Immunohistochemistry-Paraffin: Septin-11 Antibody [NBP1-83824]

Staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.
Septin-11 Antibody Immunohistochemistry-Paraffin: Septin-11 Antibody [NBP1-83824]

Immunohistochemistry-Paraffin: Septin-11 Antibody [NBP1-83824]

Staining of human cerebral cortex shows moderate cytoplasmic positivity in neuropil.
Septin-11 Antibody Immunohistochemistry-Paraffin: Septin-11 Antibody [NBP1-83824]

Immunohistochemistry-Paraffin: Septin-11 Antibody [NBP1-83824]

Staining of human skin shows no positivity in squamous epithelial cells as expected.
Septin-11 Antibody Immunohistochemistry-Paraffin: Septin-11 Antibody [NBP1-83824]

Immunohistochemistry-Paraffin: Septin-11 Antibody [NBP1-83824]

Staining of human lymph node shows moderate cytoplasmic/membranous positivity in non-germinal center cells.

Applications for Septin-6 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Septin-6

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq]

Alternate Names

KIAA0128SEP2septin 2, MGC16619, MGC20339, SEPT2, septin 6, septin-6

Entrez Gene IDs

55752 (Human); 52398 (Mouse); 305227 (Rat)

Gene Symbol

SEPTIN11

UniProt

Q9NVA2 (Human)

Additional Septin-6 Products

Product Documents for Septin-6 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Septin-6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Septin-6 Antibody

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Protocols

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