SERBP1 Antibody (SERBP1/3493)

Novus Biologicals | Catalog # NBP2-79805

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # SERBP1/3493
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Product Specifications

Immunogen

Recombinant fragment of human SERBP1 protein (around aa3-139) (exact sequence is proprietary) (Uniprot: Q8NC51)

Localization

Cytoplasm and nucleus. Also found in perinuclear regions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-79939)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Scientific Data Images for SERBP1 Antibody (SERBP1/3493)

Western Blot: SERBP1 Antibody (SERBP1/3493) [NBP2-79805]

Western Blot: SERBP1 Antibody (SERBP1/3493) [NBP2-79805]

Western Blot: SERBP1 Antibody (SERBP1/3493) [NBP2-79805] - Staining on human testis (Formalin-Fixed Paraffin-Embedded (FFPE)) Image using the Azide and BSA Free format of this antibody.
Immunohistochemistry-Paraffin: SERBP1 Antibody (SERBP1/3493) [NBP2-79805]

Immunohistochemistry-Paraffin: SERBP1 Antibody (SERBP1/3493) [NBP2-79805]

Immunohistochemistry-Paraffin: SERBP1 Antibody (SERBP1/3493) [NBP2-79805] - Formalin-fixed, paraffin-embedded human Urothelial Carcinoma stained with SERBP1 Antibody (SERBP1/3493).
Immunohistochemistry-Paraffin: SERBP1 Antibody (SERBP1/3493) [NBP2-79805]

Immunohistochemistry-Paraffin: SERBP1 Antibody (SERBP1/3493) [NBP2-79805]

Immunohistochemistry-Paraffin: SERBP1 Antibody (SERBP1/3493) [NBP2-79805] - Formalin-fixed, paraffin-embedded human Urothelial Carcinoma stained with SERBP1 Antibody (SERBP1/3493).
Protein Array: SERBP1 Antibody (SERBP1/3493) [NBP2-79805]

Protein Array: SERBP1 Antibody (SERBP1/3493) [NBP2-79805]

Protein Array: SERBP1 Antibody (SERBP1/3493) [NBP2-79805] - Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Applications for SERBP1 Antibody (SERBP1/3493)

Application
Recommended Usage

Immunohistochemistry

1-2 ug/ml

Immunohistochemistry-Paraffin

1-2 ug/ml

Western Blot

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: SERBP1

SERBP1 may play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of messagedecay

Alternate Names

CGI-55, CHD3IP, chromodomain helicase DNA binding protein 3 interacting protein, DKFZP564M2423, HABP4L, PAI-1 mRNA binding protein, PAI1 RNA-binding protein 1, PAI-RBP1DKFZp564M2423, PAIRBP1FLJ90489, plasminogen activator inhibitor 1 RNA binding protein, plasminogen activator inhibitor 1 RNA-binding protein, SERPINE1 mRNA binding protein 1, SERPINE1 mRNA-binding protein 1

Gene Symbol

SERBP1

UniProt

Additional SERBP1 Products

Product Documents for SERBP1 Antibody (SERBP1/3493)

Certificate of Analysis

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Product Specific Notices for SERBP1 Antibody (SERBP1/3493)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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