Serotonin hydrochloride

  ( 8 citations )    
Product Datasheet
Catalog Number:3547
Alternate Names:5-Hydroxytryptamine, 5-HT
Chemical Name:3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride
Product Details
Citations (8)
Supplemental Products
Reviews
Biological Activity
Endogenous agonist at 5-HT receptors and endogenous substrate for 5-HT transporters. Neurotransmitter that has roles in regulation of mood, emesis, sexuality, sleep and appetite in vivo. Caged serotonin is also available (Cat.No. 3991).
Technical Data
  • M.Wt:
    212.68
  • Formula:
    C10H12N2O.HCl
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at +4°C
  • CAS No:
    153-98-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Serotonin hydrochloride include:

8 Citations: Showing 1 - 8
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  1. Immunomodulatory capacity of the serotonin receptor 5-HT2B in a subset of human dendritic cells.
    Authors: Szabo
    Sci Rep  2018;8(1):1765
  2. Increased serotonin transporter expression reduces fear and recruitment of parvalbumin interneurons of the amygdala.
    Authors: Bocchio Et al.
    Neuropsychopharmacology  2015;40:3015
  3. A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster.
    Authors: Haynes Et al.
    BMC Vet Res  2015;4
  4. Pronociceptive and antinociceptive effects of buprenorphine in the spinal cord dorsal horn cover a dose range of four orders of magnitude.
    Authors: Gerhold Et al.
    J Neurosci  2015;35:9580
  5. The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line.
    Authors: Bracha Et al.
    Am J Physiol Regul Integr Comp Physiol  2013;9:251
  6. Essential role of brain-derived neurotrophic factor in the regulation of serotonin transmission in the basolateral amygdala.
    Authors: Daftary Et al.
    Neuroscience  2012;224:125
  7. Investigating the effect of emetic compounds on chemotaxis in Dictyostelium identifies a non-sentient model for bitter and hot tastant research.
    Authors: Robery Et al.
    PLoS One  2011;6:e24439
  8. 5-HT1A-like receptor activation inhibits abstinence-induced methamphetamine withdrawal in planarians.
    Authors: Rawls Et al.
    Neurosci Lett  2010;484:113

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