Simple Plex Control for Human SCF/c-kit Ligand

Name: Simple Plex Control for Human SCF/c-kit Ligand
Brand: R&D Systems
SKU: 898316
Price: 150 USD
Availability: InStock

R&D Systems | Catalog # 898316

Submit a review

Citations

Product Documents

Control for use with Human SCF/c-kit Ligand Simple Plex Cartridge Kit

Product Summary
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Applications

Control, Simple Plex Automated Immunoassay

Product Summary for Simple Plex Control for Human SCF/c-kit Ligand

INTENDED USE AND DESCRIPTION: For use a quantitative control for the determination of human SCF/c-kit Ligand concentrations in biological fluids. Controls are supplied lyophilized. Please refer to the lot specific certificate of analysis and Simple Plex Lyophilized Quality Control product insert for additional information.

Formulation, Preparation, and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

• Store lyophilized controls at 2-8 °C. Lyophilized controls are stable for up to 12 months from date of receipt.
• Reconstituted controls are stable for up to 6 months from date of preparation when stored at ≤ -70 °C. Storage at -20° C is not recommended.
• Individual frozen aliquots of low and high controls are designed as single-use entities. Thaw directly before use and discard any remaining volume.

Background: SCF/c-kit Ligand

SCF (Stem cell factor), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF) promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. SCF is expressed as a transmembrane, but a soluble form can be released by proteolytic shedding. Noncovalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/c-kit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial infarction by increasing the number of cardiomyocytes and vascular channels.