Catalog Number: 1447
Chemical Name: (±)-6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine hydrobromide
Biological Activity
Dopamine D1-like receptor agonist. Centrally active following systemic administration in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in water
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Relative dopamine D1 and D2 receptor affinity and efficacy determine whether dopamine agonists induce hyperactivity or oral stereotypy in rats.
    Arnt et al.
    Pharmacol.Toxicol., 1988;62:121
  2. Pharmacological characterization of the discriminative stimulus properties of the dopamine D1 agonist, SKF 81297.
    Reavill et al.
    Behav.Pharmacol., 1993;4:135
  3. The effects of dopamine D1 and D2 receptor agonists and antagonists in monkeys withdrawn from long-term neuroleptic treatment.
    Peacock et al.
    Eur.J.Pharmacol., 1990;186:49
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