SKF 81297 hydrobromide

  ( 18 citations ) ( 1 Review )    
Product Datasheet
Catalog Number:1447
Chemical Name:(±)-6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine hydrobromide
Product Details
Citations (18)
Supplemental Products
Reviews
Biological Activity
Dopamine D1-like receptor agonist. Centrally active following systemic administration in vivo.
Technical Data
  • M.Wt:
    370.67
  • Formula:
    C16H16ClNO2.HBr
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in water
  • Purity:
    >98
  • Storage:
    Desiccate at +4°C
  • CAS No:
    67287-39-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for SKF 81297 hydrobromide include:

18 Citations: Showing 1 - 10
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  1. Dopamine D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice.
    Authors: Guo
    Aging Cell  2017;16(6):1323
  2. The First Alcohol Drink Triggers mTORC1-Dependent Synaptic Plasticity in Nucleus Accumbens Dopamine D1 Receptor Neurons.
    Authors: Beckley Et al.
    J Neurosci  2016;36:701
  3. Dopaminergic modulation of appetitive trace conditioning: the role of D1 receptors in medial prefrontal cortex.
    Authors: Pezze Et al.
    Mol Med Rep  2015;232:2669
  4. Effect of dopaminergic D1 receptors on plasticity is dependent of serotoninergic 5-HT1A receptors in L5-pyramidal neurons of the prefrontal cortex.
    Authors: Meunier Et al.
    PLoS One  2015;10:e0120286
  5. PFOS induces behavioral alterations, including spontaneous hyperactivity that is corrected by dexamfetamine in zebrafish larvae.
    Authors: Spulber Et al.
    PLoS One  2014;9:e94227
  6. Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine.
    Authors: Parnaudeau Et al.
    Front Behav Neurosci  2014;8:35
  7. Dopaminergic modulation of GABAergic transmission in the entorhinal cortex: concerted roles of α1 adrenoreceptors, inward rectifier K+, and T-type Ca2+ channels.
    Authors: Cilz Et al.
    Cereb Cortex  2014;24:3195
  8. Dopamine signaling leads to loss of Polycomb repression and aberrant gene activation in experimental parkinsonism.
    Authors: Södersten Et al.
    PLoS Genet  2014;10:e1004574
  9. GPR88 reveals a discrete function of primary cilia as selective insulators of GPCR cross-talk.
    Authors: Marley Et al.
    Psychopharmacology (Berl)  2013;8:e70857
  10. Coincidence signaling of dopamine D1-like and M1 muscarinic receptors in the regulation of cyclic AMP formation and CREB phosphorylation in mouse prefrontal cortex.
    Authors: Olianas Et al.
    Neurosignals  2012;21:61
  11. Dopaminergic modulation of the hippocampal neuropil proteome identified by bioorthogonal noncanonical amino acid tagging (BONCAT).
    Authors: Hodas Et al.
    Proteomics  2012;12:2464
  12. Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris.
    Authors: Guha Et al.
    J Neurochem  2012;122:823
  13. CODA-RET reveals functional selectivity as a result of GPCR heteromerization.
    Authors: Urizar Et al.
    Nat Neurosci  2011;7:624
  14. Dopamine-induced plasticity, phospholipase D (PLD) activity and cocaine-cue behavior depend on PLD-linked metabotropic glutamate receptors in amygdala.
    Authors: Krishnan Et al.
    PLoS One  2011;6:e25639
  15. Casein kinase 1 enables nucleus accumbens amphetamine-induced locomotion by regulating AMPA receptor phosphorylation.
    Authors: Li Et al.
    J Neurochem  2011;118:237
  16. MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants.
    Authors: Deng Et al.
    PLoS One  2010;13:1128
  17. D1-like dopamine receptor activation modulates GABAergic inhibition but not electrical coupling between neocortical fast-spiking interneurons.
    Authors: Towers and Hestrin
    J Neurosci  2008;28:2633
  18. Dopaminergic regulation of inhibitory and excitatory transmission in the basolateral amygdala-prefrontal cortical pathway.
    Authors: Floresco and Tse
    J Neurosci  2007;27:2045
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Average Rating: 5 (Based on 1 review)

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  Human Xiangping Chu 01/04/2018
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Species Human

Other Experimental Details

Other Experimental Details It is very easy to dissolve the product

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