Biological Activity Non-lipid sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM). Induces CDK1-dependent apoptosis in human acute myeloid leukemia cell lines. Active in vivo.
Soluble to 100 mM in DMSO
Store at -20°C
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For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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