SMIFH2

Catalog # Availability Size / Price Qty
4401/10
4401/50
Actin-related Products Small Molecule
1 Image
Description: FH2 domain inhibitor; prevents actin nucleation

Chemical Name: 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione

Purity: ≥99%

Product Details
Citations (8)
Reviews

Biological Activity

Inhibitor of formin homology 2 (FH2) domains. Prevents formin-mediated actin nucleation and barbed end elongation. Disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts.

Technical Data

M.Wt:
377.21
Formula:
C15H9BrN2O3S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
340316-62-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for SMIFH2

The citations listed below are publications that use Tocris products. Selected citations for SMIFH2 include:

8 Citations: Showing 1 - 8

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