Somatostatin R4/SSTR4 Antibody (HL2933)

Novus Biologicals | Catalog # NBP3-48752

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # HL2933
View all Somatostatin R4/SSTR4 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide encompassing a sequence within the Extracellular domain of human Somatostatin R4/SSTR4. The exact sequence is proprietary.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Somatostatin R4/SSTR4 Antibody (HL2933)

Somatostatin R4/SSTR4 Antibody (HL2933)

Immunohistochemistry-Paraffin: Somatostatin R4/SSTR4 Antibody (HL2933) [NBP3-48752] -

Somatostatin R4/SSTR4 antibody [HL2933] detects Somatostatin R4/SSTR4 protein by immunohistochemical analysis.
Sample: Paraffin-embedded human colon cancer.Somatostatin R4/SSTR4 stained by Somatostatin R4/SSTR4 antibody [HL2933] (NBP3-48752) diluted at 1:100.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Somatostatin R4/SSTR4 Antibody (HL2933)

Western Blot: Somatostatin R4/SSTR4 Antibody (HL2933) [NBP3-48752] -

Non-transfected (-) and transfected (+) boiled and unboiled 293T whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Somatostatin R4/SSTR4 antibody [HL2933] (NBP3-48752) diluted at 1:30000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Somatostatin R4/SSTR4 Antibody (HL2933)

Western Blot: Somatostatin R4/SSTR4 Antibody (HL2933) [NBP3-48752] -

Unboiled Non-transfected (-) and transfected (+) 293T and Expi293 whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Somatostatin R4/SSTR4 antibody [HL2933] (NBP3-48752) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for Somatostatin R4/SSTR4 Antibody (HL2933)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:100-1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Somatostatin R4/SSTR4

SSTR4 has been reported to be expressed in brain, gastrointestinal tract, pancreas, and prostate tissues. No ESTs have been identified. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This "turn-off" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Long Name

Somatostatin Receptor Type 4

Alternate Names

SomatostatinR4, SS4R, SSTR4

Gene Symbol

SSTR4

Additional Somatostatin R4/SSTR4 Products

Product Documents for Somatostatin R4/SSTR4 Antibody (HL2933)

Certificate of Analysis

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Product Specific Notices for Somatostatin R4/SSTR4 Antibody (HL2933)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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