Somatostatin R5/SSTR5 Antibody

Novus Biologicals | Catalog # NB100-74540

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Porcine

Cited:

Human, Mouse, Porcine

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, Flow Cytometry, Immunocytochemistry

Cited:

Western Blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all Somatostatin R5/SSTR5 Primary Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues Q(344) E A T R P A H R A A A N G L M Q T S K L(364) of human SSTR5.

Reactivity Notes

Porcine reactivity reported in scientific literature (PMID:33002813)

Specificity

Somatostatin Receptor 5

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Somatostatin R5/SSTR5 Antibody

Western Blot: Somatostatin R5/SSTR5 Antibody [NB100-74540]

Western Blot: Somatostatin R5/SSTR5 Antibody [NB100-74540]

Western Blot: Somatostatin R5/SSTR5 Antibody [NB100-74540] - Analysis of SSTR5 in human pituitary gland.
Flow Cytometry: Somatostatin R5/SSTR5 Antibody [NB100-74540]

Flow Cytometry: Somatostatin R5/SSTR5 Antibody [NB100-74540]

Flow Cytometry: Somatostatin R5/SSTR5 Antibody [NB100-74540] - Analysis of Somatostatin Receptor 5 was done on HT-29 cells.

Applications for Somatostatin R5/SSTR5 Antibody

Application
Recommended Usage

Flow Cytometry

3 - 5 ug / 10^6 cells

Immunocytochemistry

1:5000

Immunohistochemistry-Paraffin

1:2500

Western Blot

1:4000 - 1:6000

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole serum

Preservative

0.05% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Somatostatin R5/SSTR5

Somatostatin Receptor Type 5 (SSTR5) has been reported to be expressed in adrenal, aorta, brain, breast, eye, heart, pancreas, prostate, skeletal muscle, small intestine, and thyroid. ESTs have been isolated from cartilage libraries. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This "turn-off" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively

Long Name

Somatostatin Receptor Type 5

Alternate Names

SomatostatinR5, SST5, SSTR5

Entrez Gene IDs

6755 (Human)

Gene Symbol

SSTR5

UniProt

P35346 (Human)

Additional Somatostatin R5/SSTR5 Products

Product Documents for Somatostatin R5/SSTR5 Antibody

Certificate of Analysis

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Product Specific Notices for Somatostatin R5/SSTR5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Somatostatin R5/SSTR5 Antibody

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Protocols

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