Splitomicin

  ( 2 citations )    
Product Datasheet
Catalog Number:1542
Chemical Name:1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one
Product Details
Citations (2)
Reviews
Biological Activity
Inhibitor of Sir2p (IC50 = 60 μM), an NAD+-dependent Sir2 family deacetylase required for chromatin-dependent silencing in yeast.
Technical Data
  • M.Wt:
    198.22
  • Formula:
    C13H10O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >97
  • Storage:
    Store at -20°C
  • CAS No:
    5690-03-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Splitomicin include:

2 Citations: Showing 1 - 2
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  1. Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor.
    Authors: Stavrou Et al.
    J Neurosci  2015;125:710
  2. Polycomb group complexes are recruited to reactivated FMR1 alleles in Fragile X syndrome in response to FMR1 transcription.
    Authors: Kumari and Usdin
    Hum Mol Genet  2014;23:6575

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