You are here

Home » Sir2-like Family Deacetylase Inhibitors » Splitomicin


Splitomicin

  ( 2 citations )    
Product Datasheet
Catalog Number:1542
Chemical Name:1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one
Product Details
Citations (2)
Reviews
Biological Activity
Inhibitor of Sir2p (IC50 = 60 μM), an NAD+-dependent Sir2 family deacetylase required for chromatin-dependent silencing in yeast.
Technical Data
  • M.Wt:
    198.22
  • Formula:
    C13H10O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >97
  • Storage:
    Store at -20°C
  • CAS No:
    5690-03-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
SDS
COA view current batch
 or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Splitomicin include:

2 Citations: Showing 1 - 2
Filter your results:

  1. Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor.
    Authors: Stavrou Et al.
    J Neurosci  2015;125:710
  2. Polycomb group complexes are recruited to reactivated FMR1 alleles in Fragile X syndrome in response to FMR1 transcription.
    Authors: Kumari and Usdin
    Hum Mol Genet  2014;23:6575

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used Splitomicin?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee