Inhibitor of activator protein-1 (AP-1) transcription factor activity that displays antitumor effects in vivo
. Does not activate transcription from the retinoic acid response element (RARE) and displays no activity at retinoic acid receptors (EC50
> 1 μ
M for RARα
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Effects of novel RAR- and RXR-selective retinoids on myeloid leukemic proliferation and differentiation in vitro.
Shiohara et al.
A new class of retinoids with selective inhibition of AP-1 inhibits proliferation.
Fanjul et al.
Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid.
Huang et al.
The citations listed below are publications that use Tocris products. Selected citations for SR 11302 include:
Showing Results 1 - 10 of 16