STAT1 Antibody (BLR125H)

Name: STAT1 Antibody (BLR125H)
Brand: Novus Biologicals
SKU: NBP3-14708
Price: 339 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-14708

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit Clone # BLR125H

View all STAT1 Primary Antibodies »

Product Specifications

Immunogen

between 400 and 450

Clonality

Monoclonal

Host

Rabbit

Scientific Data Images for STAT1 Antibody (BLR125H)

Immunoprecipitation: STAT1 Antibody (BLR125H) [NBP3-14708]

Immunoprecipitation: STAT1 Antibody [NBP3-14708] - Whole cell lysate (1.0 mgper IP reaction; 20% of IP loaded) from 293T cells preparedusing NETN lysis buffer. Antibodies: Rabbit anti-STAT1recombinant monoclonal antibody used for IP at 20 ul/mg lysate. STAT1 was alsoimmunoprecipitated by rabbit anti-STAT1 antibodyA302-753A. For blotting immunoprecipitated STAT1, was used at 1:1000. Chemiluminescence withan exposure time of 75 seconds.

Applications for STAT1 Antibody (BLR125H)

Application

Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

>95%

Formulation

Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: STAT1

STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, and Stat6), Stat1, Stat3, Stat5a, and Stat5b have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-a, IFN-b, IFN-g and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1). STAT1 has two forms, the 91 kDa STAT1a and the 84 kDa STAT1b which are encoded by the same gene with splicing variant.

Long Name

Signal Transducer and Activator of Transcription 1

Alternate Names

CANDF7, ISGF-3, STAT91

Gene Symbol

STAT1

Additional STAT1 Products

Product Documents for STAT1 Antibody (BLR125H)

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Product Specific Notices for STAT1 Antibody (BLR125H)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.